diclofenac has been researched along with Vomiting in 18 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery." | 9.08 | Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995) |
| "Forty children undergoing strabismus surgery as day patients were randomly allocated to receive oxybuprocaine 0." | 9.08 | Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery. ( Benham, SW; Lawson, RA; McNicol, LR; Morton, NS, 1997) |
| "At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy." | 9.07 | Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993) |
| "Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)." | 6.68 | Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997) |
| "There was no statistical difference in the mean reduction in pain score between any of the combinations at any point, although combination therapy was the first to reach a clinically significant reduction in pain score (<13 mm), and diclofenac-paracetamol combinations consistently produced a greater reduction in mean pain score than either nonsteroidal antiinflammatory drugs or paracetamol alone." | 5.11 | Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury. ( Lam, PK; Man, SY; Rainer, TH; Woo, WW, 2005) |
| "This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery." | 5.08 | Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995) |
| "Forty children undergoing strabismus surgery as day patients were randomly allocated to receive oxybuprocaine 0." | 5.08 | Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery. ( Benham, SW; Lawson, RA; McNicol, LR; Morton, NS, 1997) |
| "At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy." | 5.07 | Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993) |
| " The five most commonly reported adverse events were abdominal pain by 23." | 3.77 | Overall safety of Arthrotec. ( Geis, GS, 1992) |
| "Pelvic pain was assessed, with a 100 mm visual analogue scale, at 1 hour, at hospital discharge, and time of first analgesia or any other time analgesia was demanded." | 2.68 | Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial. ( Breeson, AJ; Ezeh, UO; Lamb, MD; Martin, JL; Shoulder, VS; Vellacott, ID, 1995) |
| "Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)." | 2.68 | Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997) |
| "Diclofenac sodium was assessed as an analgesic for postoperative pain following paediatric tonsillectomy in a randomised double blind trial." | 2.66 | Diclofenac sodium for post-tonsillectomy pain in children. ( Campbell, W; Mathews, HM; Patterson, CC; Watters, CH, 1988) |
| "Diclofenac-potassium was developed as an immediate-release tablet with the aim of providing rapid onset of action after oral administration." | 2.40 | Diclofenac-potassium in migraine: a review. ( Goa, KL; McNeely, W, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watzer, B | 1 |
| Lusthof, KJ | 1 |
| Schweer, H | 1 |
| Zuniga, JR | 1 |
| Malmström, H | 1 |
| Noveck, RJ | 1 |
| Campbell, JH | 1 |
| Christensen, S | 1 |
| Glickman, RS | 1 |
| Tomasetti, BJ | 1 |
| Boesing, SE | 1 |
| Williams, DG | 1 |
| Patel, A | 1 |
| Howard, RF | 1 |
| Woo, WW | 1 |
| Man, SY | 1 |
| Lam, PK | 1 |
| Rainer, TH | 1 |
| Ezeh, UO | 1 |
| Shoulder, VS | 1 |
| Martin, JL | 1 |
| Breeson, AJ | 1 |
| Lamb, MD | 1 |
| Vellacott, ID | 1 |
| Karabinis, A | 1 |
| Rigas, K | 1 |
| Mega, AM | 1 |
| Thomopoulos, G | 1 |
| Klouva, F | 1 |
| Bilalis, D | 1 |
| Hovorka, J | 1 |
| Kallela, H | 1 |
| Korttila, K | 1 |
| Hyndman, J | 1 |
| Mikawa, K | 2 |
| Nishina, K | 2 |
| Maekawa, N | 2 |
| Asano, M | 1 |
| Obara, H | 2 |
| Stein, A | 1 |
| Ben Dov, D | 1 |
| Finkel, B | 1 |
| Mecz, Y | 1 |
| Kitzes, R | 1 |
| Lurie, A | 1 |
| Mendham, JE | 1 |
| Mather, SJ | 1 |
| Shiga, M | 1 |
| Morton, NS | 1 |
| Benham, SW | 1 |
| Lawson, RA | 1 |
| McNicol, LR | 1 |
| Moriarty, A | 1 |
| McNeely, W | 1 |
| Goa, KL | 1 |
| Tausch, G | 1 |
| Eberl, R | 1 |
| Tuschl, P | 1 |
| Geis, GS | 1 |
| Watters, CH | 1 |
| Patterson, CC | 1 |
| Mathews, HM | 1 |
| Campbell, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy[NCT01267136] | Phase 4 | 84 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Average number of post-operative days with pain score >4/10. Pain score assessments were administered once daily by parents using either the Numeric Rating Scale (NRS-11) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 8-15 (von Baeyer et al., 2009) or the Faces Pain Scale-Revised (FPS-R) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 4-10 (Hicks et al., 2001). (NCT01267136)
Timeframe: Efficacy was assessed daily during the 10-day postoperative recovery period.
| Intervention | days (Median) |
|---|---|
| Capital® With Codeine Suspension | 1.5 |
| Tramadol Suspension | 1 |
Parent-reported side effects entered in 10-day diary. (NCT01267136)
Timeframe: Side effects will be observed and recorded daily by caregivers for a total of 10 days in the take-home diary.
| Intervention | participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Nausea | Vomiting | Fever | Itching | Rash | Sweating | Dizziness | Headache | Constipation | Oversedation | Tonsil bleed | |
| Capital® With Codeine Suspension | 20 | 21 | 11 | 5 | 1 | 9 | 15 | 12 | 21 | 14 | 3 |
| Tramadol Suspension | 20 | 18 | 10 | 12 | 1 | 7 | 17 | 17 | 21 | 8 | 0 |
2 reviews available for diclofenac and Vomiting
| Article | Year |
|---|---|
Diclofenac-potassium in migraine: a review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Humans; Migraine Diso | 1999 |
Overall safety of Arthrotec.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Constipation; Diarrhea; | 1992 |
13 trials available for diclofenac and Vomiting
| Article | Year |
|---|---|
Controlled phase III clinical trial of diclofenac potassium liquid-filled soft gelatin capsule for treatment of postoperative dental pain.
Topics: Absorption; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Stero | 2010 |
Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability.
Topics: Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Stimu | 2002 |
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dizziness; Female; Humans | 2005 |
Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial.
Topics: Adult; Cyclizine; Diclofenac; Double-Blind Method; Female; Gels; Humans; Laparoscopy; Lidocaine; Mef | 1995 |
Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy.
Topics: Acetaminophen; Adult; Ambulatory Care; Diclofenac; Double-Blind Method; Female; Fentanyl; Humans; In | 1993 |
Oral clonidine premedication reduces vomiting in children after strabismus surgery.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anti-Inflammatory Agents, N | 1995 |
Single-dose intramuscular ketorolac versus diclofenac for pain management in renal colic.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Double-Blind Method; Female | 1996 |
Comparison of diclofenac and tenoxicam for postoperative analgesia with and without fentanyl in children undergoing adenotonsillectomy or tonsillectomy.
Topics: Adenoidectomy; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Ch | 1996 |
Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery.
Topics: Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesia; Anesthesia, General; Anesthetics, Local; Anti-Inflammator | 1997 |
[Clinical experiences and results of clinical experimental studies with Voltaren in rheumatic diseases].
Topics: Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Diclofenac; DNA Repair; Drug Evalu | 1976 |
Overall safety of Arthrotec.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Constipation; Diarrhea; | 1992 |
Diclofenac sodium for post-tonsillectomy pain in children.
Topics: Anesthesia Recovery Period; Child; Child, Preschool; Diclofenac; Female; Humans; Male; Meperidine; P | 1988 |
4 other studies available for diclofenac and Vomiting
| Article | Year |
|---|---|
Abortion after deliberate Arthrotec® addition to food. Mass spectrometric detection of diclofenac, misoprostol acid, and their urinary metabolites.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Chromatography, Liquid; Crime; Diclofenac; Fa | 2015 |
[Spontaneous rupture of the esophagus masked by the ingestion of a non-steroidal anti-inflammatory agent].
Topics: Diclofenac; Esophageal Diseases; Fatal Outcome; Humans; Male; Middle Aged; Motion Sickness; Rupture, | 1993 |
Oral premedication with methadone, promethazine and diclofenac.
Topics: Administration, Oral; Anxiety; Diclofenac; Female; Humans; Male; Methadone; Pain, Postoperative; Pre | 1993 |
Use of Ropivacaine in postoperative infusions.
Topics: Abdomen; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agen | 1997 |