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diclofenac and Uveitis

diclofenac has been researched along with Uveitis in 14 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To compare the effect of intravitreal diclofenac (IVD) versus intravitreal triamcinolone (IVT) on refractory uveitic cystoid macular edema (CME)."9.17A pilot study of intravitreal diclofenac versus intravitreal triamcinolone for uveitic cystoid macular edema. ( Eskandari, A; Rabbanikhah, Z; Ramezani, A; Soheilian, M; Soheilian, R, 2013)
"Intravitreal diclofenac (IVD) may be a promising treatment for refractory uveitis-associated CME."7.88Intravitreal diclofenac for treatment of refractory uveitis-associated cystoid macular oedema: A before and after clinical study. ( Kianersi, F; Kianersi, H; Pourazizi, M; Rezaeian-Ramsheh, A, 2018)
"We studied if tobramycin associated to sodium diclofenac modifies the drug effect of the latter on arachidonic acid metabolism in an endotoxin induced uveitis (EIU) model in albino rabbits."7.71[Effect of tobramycin with topical diclofenac on arachidonic acid in endotoxin-induced uveitis]. ( Alió y Sanz, J; Honrubia López, FM; Ruiz Moreno, JM; Ruiz Moreno, O; Vélez, P, 2001)
"Ophthalmologic adverse effects of bisphosphonate therapy are infrequent and of unclear pathogenesis."6.41Uveitis, an under-recognized adverse effect of pamidronate. Case report and literature review. ( Acquaviva, PC; Bernard, P; Dahan, L; Daumen-Legré, V; Lafforgue, P; Pham, T; Rey, J, 2000)
"To compare the effect of intravitreal diclofenac (IVD) versus intravitreal triamcinolone (IVT) on refractory uveitic cystoid macular edema (CME)."5.17A pilot study of intravitreal diclofenac versus intravitreal triamcinolone for uveitic cystoid macular edema. ( Eskandari, A; Rabbanikhah, Z; Ramezani, A; Soheilian, M; Soheilian, R, 2013)
"Intravitreal diclofenac (IVD) may be a promising treatment for refractory uveitis-associated CME."3.88Intravitreal diclofenac for treatment of refractory uveitis-associated cystoid macular oedema: A before and after clinical study. ( Kianersi, F; Kianersi, H; Pourazizi, M; Rezaeian-Ramsheh, A, 2018)
"We studied if tobramycin associated to sodium diclofenac modifies the drug effect of the latter on arachidonic acid metabolism in an endotoxin induced uveitis (EIU) model in albino rabbits."3.71[Effect of tobramycin with topical diclofenac on arachidonic acid in endotoxin-induced uveitis]. ( Alió y Sanz, J; Honrubia López, FM; Ruiz Moreno, JM; Ruiz Moreno, O; Vélez, P, 2001)
" Indomethacin (IM) enhanced TNF production in all the eight TCC that were established from a patient with human T lymphotrophic virus type 1 uveitis or pulmonary sarcoidosis, and suppressed IL-6 production in six of the eight TCC, without affecting their low levels of PGE2 production."3.69Nonsteroidal anti-inflammatory drugs differentially regulate cytokine production in human lymphocytes: up-regulation of TNF, IFN-gamma and IL-2, in contrast to down-regulation of IL-6 production. ( Itoh, K; Nakao, M; Shichijo, S; Tanaka, H; Tsuboi, I, 1995)
"Initial angiographic cystoid macular edema was comparable and significantly improved after therapy in the two treatment groups."2.67[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]. ( Guex-Crosier, Y; Herbort, CP; Othenin-Girard, P, 1992)
"Ophthalmologic adverse effects of bisphosphonate therapy are infrequent and of unclear pathogenesis."2.41Uveitis, an under-recognized adverse effect of pamidronate. Case report and literature review. ( Acquaviva, PC; Bernard, P; Dahan, L; Daumen-Legré, V; Lafforgue, P; Pham, T; Rey, J, 2000)
"Eyes treated with ketorolac and diclofenac demonstrated reduced aqueous leucocyte concentrations of 62% and 64% respectively, compared with untreated controls (p<0."1.35Efficacy and pharmacokinetics of intravitreal non-steroidal anti-inflammatory drugs for intraocular inflammation. ( Barañano, DE; Durairaj, C; Edelhauser, HF; Handa, JT; Kim, SJ; Kompella, UB, 2009)
"Diclofenac levels were measured by HPLC in the cornea, aqueous humor (AH), iris/ciliary body (ICB) and plasma 30 min, 1, 3, 6 and 12 h after application."1.30The ocular pharmacokinetics of topical diclofenac is affected by ocular inflammation. ( Alcoriza, N; Bellot, JL; García-Cabanes, C; Orts, A; Palmero, M, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's6 (42.86)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kianersi, F1
Rezaeian-Ramsheh, A1
Pourazizi, M1
Kianersi, H1
Soheilian, M1
Eskandari, A1
Ramezani, A1
Rabbanikhah, Z1
Soheilian, R1
Barañano, DE1
Kim, SJ1
Edelhauser, HF1
Durairaj, C1
Kompella, UB1
Handa, JT1
Kobayashi, S1
Tamura, N1
Ikeda, M1
Sakuraba, K1
Matsumoto, T1
Hashimoto, H1
Agata, M1
Abe, T1
Kon, M1
Tanaka, M1
Kimura, T1
Nakajima, A1
Herbort, CP2
Tsuboi, I1
Tanaka, H1
Nakao, M1
Shichijo, S1
Itoh, K1
Bellot, JL2
Palmero, M2
García-Cabanes, C2
Espí, R1
Hariton, C1
Orts, A2
Kulkarni, PS1
Paterson, CA1
Alcoriza, N1
Rey, J1
Daumen-Legré, V1
Pham, T1
Bernard, P1
Dahan, L1
Acquaviva, PC1
Lafforgue, P1
Ruiz Moreno, O1
Ruiz Moreno, JM1
Vélez, P1
Alió y Sanz, J1
Honrubia López, FM1
Guex-Crosier, Y1
Othenin-Girard, P1
Deray, G1
Le Hoang, P1
Aupetit, B1
Achour, A1
Rottembourg, J1
Baumelou, A1

Reviews

1 review available for diclofenac and Uveitis

ArticleYear
Uveitis, an under-recognized adverse effect of pamidronate. Case report and literature review.
    Joint bone spine, 2000, Volume: 67, Issue:4

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Diclofenac; Diphos

2000

Trials

2 trials available for diclofenac and Uveitis

ArticleYear
A pilot study of intravitreal diclofenac versus intravitreal triamcinolone for uveitic cystoid macular edema.
    Ocular immunology and inflammation, 2013, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Follow-Up Stud

2013
[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema].
    Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Injections; Lenses, Intra

1992

Other Studies

11 other studies available for diclofenac and Uveitis

ArticleYear
Intravitreal diclofenac for treatment of refractory uveitis-associated cystoid macular oedema: A before and after clinical study.
    Acta ophthalmologica, 2018, Volume: 96, Issue:3

    Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Fluoresc

2018
Efficacy and pharmacokinetics of intravitreal non-steroidal anti-inflammatory drugs for intraocular inflammation.
    The British journal of ophthalmology, 2009, Volume: 93, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac;

2009
Uveitis in adult patients with poststreptococcal reactive arthritis: the first two cases reported associated with uveitis.
    Clinical rheumatology, 2002, Volume: 21, Issue:6

    Topics: Adult; Ampicillin; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Arthritis, React

2002
[Effect of topical diclofenac sodium, a non-steroidal anti-inflammatory drug, on various ocular inflammatory models in animals].
    Nippon Ganka Gakkai zasshi, 1983, Volume: 87, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclofenac; Eye Diseases;

1983
Uveoscleritis after excessive neodymium:YAG laser posterior capsulotomy.
    Journal of cataract and refractive surgery, 1994, Volume: 20, Issue:1

    Topics: Aged; Cataract Extraction; Dexamethasone; Diclofenac; Female; Humans; Laser Therapy; Lens Capsule, C

1994
Nonsteroidal anti-inflammatory drugs differentially regulate cytokine production in human lymphocytes: up-regulation of TNF, IFN-gamma and IL-2, in contrast to down-regulation of IL-6 production.
    Cytokine, 1995, Volume: 7, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Cells, Cultured; Clone Cells; Diclofenac; Di

1995
Additive effect of nitric oxide and prostaglandin-E2 synthesis inhibitors in endotoxin-induced uveitis in the rabbit.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:4

    Topics: Administration, Topical; Animals; Aqueous Humor; Arginine; Ciliary Body; Cyclooxygenase Inhibitors;

1996
Diclofenac and prednisolone inhibit endotoxin-induced uveitis in rabbits.
    Experimental eye research, 1995, Volume: 61, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Diclofenac; Endotoxins; Prednisolone; Rabbits; Uveitis

1995
The ocular pharmacokinetics of topical diclofenac is affected by ocular inflammation.
    Ophthalmic research, 1999, Volume: 31, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pres

1999
[Effect of tobramycin with topical diclofenac on arachidonic acid in endotoxin-induced uveitis].
    Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Bacterial To

2001
Enhancement of cyclosporine A nephrotoxicity by diclofenac.
    Clinical nephrology, 1987, Volume: 27, Issue:4

    Topics: Acute Kidney Injury; Back Pain; Cyclosporins; Diclofenac; Drug Synergism; Humans; Male; Middle Aged;

1987