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diclofenac and Ureteral Obstruction

diclofenac has been researched along with Ureteral Obstruction in 9 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.

Research Excerpts

ExcerptRelevanceReference
"(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract."5.35Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009)
"Diclofenac treatment can lead to overestimation in ureteral stone disease, by delaying renal excretion bilaterally, but predominantly on the side of calculus."5.31Diclofenac treatment prolongs renal transit time in acute ureteral obstruction: a renographic study. ( Jacobsson, H; Kinn, AC; Larsson, SA; Nelson, E, 2000)
"Misoprostol was not observed to have any protective effect against diclofenac in obstructed kidneys."2.80Oral misoprostol does not protect the kidneys from diclofenac induced toxicity: data from an unilateral ureteral obstructive rat model. ( Aydogmus, Y; Buyukserbetci, M; Dadali, M; Eroglu, M; Hascicek, AM; Huri, E; Kilinc, AS; Ogus, E; Ozer, E, 2015)
"Treatment with diclofenac sodium during a relatively long period of reversible unilateral ureteric obstruction, similar to its use in the management of ureteric colic, appears to ameliorate the alterations in the hemodynamic glomerular functions at least 2 weeks following the reversal of obstruction."1.37The effect of diclofenac sodium on renal function in reversible unilateral ureteric obstruction. ( Hammad, FT; Lubbad, L, 2011)
"(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract."1.35Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009)
"Valdecoxib was more potent in proximal specimens of human ureter (EC50=7."1.35Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo. ( Chaignat, V; Danuser, H; Mevissen, M; Stoffel, MH; Studer, UE; Z'brun, S, 2008)
"Diclofenac treatment can lead to overestimation in ureteral stone disease, by delaying renal excretion bilaterally, but predominantly on the side of calculus."1.31Diclofenac treatment prolongs renal transit time in acute ureteral obstruction: a renographic study. ( Jacobsson, H; Kinn, AC; Larsson, SA; Nelson, E, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buyukserbetci, M1
Dadali, M1
Aydogmus, Y1
Huri, E1
Hascicek, AM1
Ozer, E1
Ogus, E1
Kilinc, AS1
Eroglu, M1
Hammad, FT1
Lubbad, L1
Modi, P1
Goel, R1
Rizvi, SJ1
Chaignat, V1
Danuser, H1
Stoffel, MH1
Z'brun, S1
Studer, UE1
Mevissen, M1
Kato, A1
Hishida, A1
Ishibashi, R1
Nakajima, T1
Ohura, M1
Furuya, R1
Kumagai, H1
Kimura, M1
Kaneko, E1
Kinn, AC1
Larsson, SA1
Nelson, E1
Jacobsson, H1
Sweeney, P1
Young, LS1
Fitzpatrick, JM1
Khalifa, MS1
Sharkawi, MA1

Trials

2 trials available for diclofenac and Ureteral Obstruction

ArticleYear
Oral misoprostol does not protect the kidneys from diclofenac induced toxicity: data from an unilateral ureteral obstructive rat model.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:18

    Topics: Administration, Oral; Animals; Diclofenac; Disease Models, Animal; Female; Kidney; Misoprostol; Rats

2015
Treatment of pain owing to acute ureteral obstruction with prostaglandin-synthetase inhibitor: a prospective randomized study.
    The Journal of urology, 1986, Volume: 136, Issue:2

    Topics: Adolescent; Adult; Butylscopolammonium Bromide; Clinical Trials as Topic; Cyclooxygenase Inhibitors;

1986

Other Studies

7 other studies available for diclofenac and Ureteral Obstruction

ArticleYear
Renal colic in adults: NSAIDs and morphine are effective for pain relief.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acetaminophen; Adult; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinic

2009
The effect of diclofenac sodium on renal function in reversible unilateral ureteric obstruction.
    Urological research, 2011, Volume: 39, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glomerular Filtration Rate; Kidney; Ki

2011
Case report: laparoscopic pyeloplasty for ureteropelvic junction obstruction of lower moiety in duplex system.
    Journal of endourology, 2007, Volume: 21, Issue:9

    Topics: Adult; Analgesia; Contrast Media; Diclofenac; Female; Glomerular Filtration Rate; Humans; Kidney; Ki

2007
Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo.
    British journal of pharmacology, 2008, Volume: 154, Issue:6

    Topics: Aged; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib

2008
Nephrogenic diabetes insipidus associated with bilateral ureteral obstruction.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:4

    Topics: Adult; Chlorothiazide; Diabetes Insipidus; Diclofenac; Humans; Ileal Neoplasms; Kidney Diseases; Lei

1994
Diclofenac treatment prolongs renal transit time in acute ureteral obstruction: a renographic study.
    European urology, 2000, Volume: 37, Issue:3

    Topics: Acute Disease; Colic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Kidney; Male; Middle Aged; Radi

2000
An autoradiographic study of regional blood flow distribution in the rat kidney during ureteric obstruction--the role of vasoactive compounds.
    BJU international, 2001, Volume: 88, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Diclofenac; Kidney; M

2001