diclofenac has been researched along with Tendinitis in 21 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Tendinitis: Inflammation of TENDONS. It is characterized by the degeneration of tendons accompanied by an inflammatory repair response, fibroblastic proliferation, and formation of granulation tissue. Tendinitis is not a clinical diagnosis and can be confirmed only by histopathological findings.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The application of topical diclofenac has been suggested as a possible treatment for Achilles tendinopathy." | 9.41 | Topical diclofenac vs placebo for the treatment of chronic Achilles tendinopathy: A randomized controlled clinical trial. ( Bovard, J; Bussin, E; Cairns, B; Fredericson, M; Gerschman, T; Scott, A, 2021) |
| "This was a double-blind study designed to compare the efficacy and tolerability of diclofenac/misoprostol and diclofenac in patients with acute tendinitis/bursitis of the shoulder." | 9.07 | Diclofenac/misoprostol vs diclofenac/placebo in treating acute episodes of tendinitis/bursitis of the shoulder. ( Zuinen, C, 1993) |
| "A prospective double blind placebo controlled study was carried out to compare the effects of subacromial injection of triamcinolone and oral diclofenac in patients with rotator cuff tendinitis over a 4-week period." | 9.06 | A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis. ( Adebajo, AO; Hazleman, BL; Nash, P, 1990) |
| "This study evaluates the therapeutic effects of iontophoresis using GNPs and diclofenac diethylammonium on inflammatory parameters in rats challenged with traumatic tendinitis." | 7.78 | Gold nanoparticles and diclofenac diethylammonium administered by iontophoresis reduce inflammatory cytokines expression in Achilles tendinitis. ( De Souza, CT; Dohnert, LH; Dohnert, MB; Luciano, TF; Paula, MM; Possato, JC; Venâncio, M; Zeferino, RC; Zugno, AI, 2012) |
| "Tendinitis is a painful condition that occurs in tendons in response to repetitive use or direct trauma." | 5.42 | Inflammatory cytokines content in Achilles tendinopathy after phonophoresis treatment combined with gold nanoparticles and diclophenac diethylammonium in rats. ( de Souza, CT; Dohnert, LH; Dohnert, MB; Ferreira, GK; Paula, MM; Silveira, PC; Zanoni, ET, 2015) |
| "The application of topical diclofenac has been suggested as a possible treatment for Achilles tendinopathy." | 5.41 | Topical diclofenac vs placebo for the treatment of chronic Achilles tendinopathy: A randomized controlled clinical trial. ( Bovard, J; Bussin, E; Cairns, B; Fredericson, M; Gerschman, T; Scott, A, 2021) |
| "To determine if a topically applied non-steroidal anti-inflammatory drug (diclofenac) can provide short-term pain relief for chronic Achilles tendinopathy (CAT), in order to inform the development of a new rehabilitation protocol." | 5.24 | Randomised controlled trial evaluating the short-term analgesic effect of topical diclofenac on chronic Achilles tendon pain: a pilot study. ( Bovard, J; Bussin, ER; Cairns, B; Scott, A, 2017) |
| "This was a double-blind study designed to compare the efficacy and tolerability of diclofenac/misoprostol and diclofenac in patients with acute tendinitis/bursitis of the shoulder." | 5.07 | Diclofenac/misoprostol vs diclofenac/placebo in treating acute episodes of tendinitis/bursitis of the shoulder. ( Zuinen, C, 1993) |
| "A prospective double blind placebo controlled study was carried out to compare the effects of subacromial injection of triamcinolone and oral diclofenac in patients with rotator cuff tendinitis over a 4-week period." | 5.06 | A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis. ( Adebajo, AO; Hazleman, BL; Nash, P, 1990) |
| "5%) dropped out in the nimesulide group (two early recovery, one lack of effect, one adverse event), compared with 13 (21." | 3.79 | Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide. ( Wober, W, 1999) |
| "This study evaluates the therapeutic effects of iontophoresis using GNPs and diclofenac diethylammonium on inflammatory parameters in rats challenged with traumatic tendinitis." | 3.78 | Gold nanoparticles and diclofenac diethylammonium administered by iontophoresis reduce inflammatory cytokines expression in Achilles tendinitis. ( De Souza, CT; Dohnert, LH; Dohnert, MB; Luciano, TF; Paula, MM; Possato, JC; Venâncio, M; Zeferino, RC; Zugno, AI, 2012) |
| "Presented are the results of four postsurgical pain studies, one study of acute gouty arthritis and nine studies of acute musculoskeletal disorders: acute low back pain, acute painful shoulder, tendinitis and bursitis, and acute sports injuries." | 3.76 | Etodolac: analgesic effects in musculoskeletal and postoperative pain. ( Pena, M, 1990) |
| "Etodolac is a new nonsteroidal anti-inflammatory drug (NSAID)." | 2.67 | Clinical response to etodolac in the management of pain. ( Mizraji, M, 1990) |
| "Tendinopathy is a common disease with a variety of treatments and therapies." | 1.42 | The low level laser therapy (LLLT) operating in 660 nm reduce gene expression of inflammatory mediators in the experimental model of collagenase-induced rat tendinitis. ( Arnold, G; Bjordal, JM; Frigo, L; Leal-Junior, EC; Lopes-Martins, RA; Magdalou, J; Marcos, RL; Pallotta, R; Rahouadj, R; Torres-Silva, R, 2015) |
| "Tendinitis is a painful condition that occurs in tendons in response to repetitive use or direct trauma." | 1.42 | Inflammatory cytokines content in Achilles tendinopathy after phonophoresis treatment combined with gold nanoparticles and diclophenac diethylammonium in rats. ( de Souza, CT; Dohnert, LH; Dohnert, MB; Ferreira, GK; Paula, MM; Silveira, PC; Zanoni, ET, 2015) |
| "Acute calcifying tendonitis of the longus colli muscle can be diagnosed using various imaging techniques, such as X-ray, CT or MRI imaging." | 1.36 | [Neck pain due to tendonitis of the longus colli muscle]. ( Coebergh, JA; de Bruijn, BF; Koppen, H; van Gils, AP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bussin, E | 1 |
| Cairns, B | 2 |
| Gerschman, T | 1 |
| Fredericson, M | 1 |
| Bovard, J | 2 |
| Scott, A | 2 |
| Bussin, ER | 1 |
| Terao, K | 1 |
| Kusunoki, T | 2 |
| Mori, K | 1 |
| Murata, K | 2 |
| Doi, K | 1 |
| Casalechi, HL | 1 |
| de Farias Marques, AC | 1 |
| da Silva, EA | 1 |
| Aimbire, F | 1 |
| Marcos, RL | 3 |
| Lopes-Martins, RA | 3 |
| de Carvalho, Pde T | 1 |
| Albertini, R | 1 |
| Torres-Silva, R | 1 |
| Bjordal, JM | 1 |
| Frigo, L | 1 |
| Rahouadj, R | 2 |
| Arnold, G | 2 |
| Leal-Junior, EC | 2 |
| Magdalou, J | 2 |
| Pallotta, R | 1 |
| Dohnert, MB | 2 |
| Ferreira, GK | 1 |
| Silveira, PC | 1 |
| Zanoni, ET | 1 |
| Dohnert, LH | 2 |
| de Souza, CT | 2 |
| Paula, MM | 2 |
| Coebergh, JA | 1 |
| Koppen, H | 1 |
| van Gils, AP | 1 |
| de Bruijn, BF | 1 |
| Venâncio, M | 1 |
| Possato, JC | 1 |
| Zeferino, RC | 1 |
| Zugno, AI | 1 |
| Luciano, TF | 1 |
| Magnenet, V | 1 |
| Wang, X | 1 |
| Demeurie, F | 1 |
| de Carvalho, MH | 1 |
| Muramoto, D | 1 |
| Schneider, C | 1 |
| Klein, P | 1 |
| Stolt, P | 1 |
| Oberbaum, M | 1 |
| Müller, JB | 1 |
| Zuinen, C | 1 |
| Galeazzi, M | 1 |
| Marcolongo, R | 1 |
| Rosenthal, M | 1 |
| Bahous, I | 1 |
| Wober, W | 1 |
| Porzsolt, F | 1 |
| Heit, W | 1 |
| Heimpel, H | 1 |
| Asbeck, F | 1 |
| Mizraji, M | 1 |
| Pena, M | 1 |
| Adebajo, AO | 1 |
| Nash, P | 1 |
| Hazleman, BL | 1 |
| Machtey, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Monoarticular Corticosteroid Injection Versus Systemic Administration in the Treatment of Rheumatoid Arthritis Patients: A Randomized Double-Blind Controlled Study[NCT00506896] | Phase 2 | 60 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections: a Prospective Double-Blinded Randomized Trial[NCT04895280] | Phase 4 | 400 participants (Anticipated) | Interventional | 2024-04-30 | Not yet recruiting | ||
| Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial[NCT04115644] | Phase 4 | 82 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Covid-19 and we failed to submit annual report for 2017 and 2018) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain as measured by the Visual Analog Scale after first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - immediately after the injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.197 |
| Group 2 (Ketorolac) | 3.577 |
| Group 3 (Kenalog) | 3.677 |
Pain as measured by the Visual Analog Scale prior to first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - pre-injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 5.77 |
| Group 2 (Ketorolac) | 4.57 |
| Group 3 (Kenalog) | 4.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Day 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 2.347 |
| Group 2 (Ketorolac) | 2.837 |
| Group 3 (Kenalog) | 2.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 1
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.397 |
| Group 2 (Ketorolac) | 3.7 |
| Group 3 (Kenalog) | 3.257 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 12
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.447 |
| Group 2 (Ketorolac) | 1.417 |
| Group 3 (Kenalog) | 2.027 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.57 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 4
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.317 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 6
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.357 |
| Group 2 (Ketorolac) | 2.757 |
| Group 3 (Kenalog) | 2.687 |
2 reviews available for diclofenac and Tendinitis
| Article | Year |
|---|---|
Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Cyclooxygenase 2; Cyclooxyg | 1999 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
10 trials available for diclofenac and Tendinitis
| Article | Year |
|---|---|
Topical diclofenac vs placebo for the treatment of chronic Achilles tendinopathy: A randomized controlled clinical trial.
Topics: Administration, Topical; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chron | 2021 |
Randomised controlled trial evaluating the short-term analgesic effect of topical diclofenac on chronic Achilles tendon pain: a pilot study.
Topics: Achilles Tendon; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Chronic Pai | 2017 |
A homeopathic ointment preparation compared with 1% diclofenac gel for acute symptomatic treatment of tendinopathy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Diclo | 2005 |
Diclofenac/misoprostol vs diclofenac/placebo in treating acute episodes of tendinitis/bursitis of the shoulder.
Topics: Adolescent; Adult; Aged; Bursitis; Diclofenac; Double-Blind Method; Drug Administration Schedule; Dr | 1993 |
A placebo-controlled study of the efficacy and tolerability of a nonsteroidal anti-inflammatory drug, DHEP plaster, in inflammatory peri- and extra-articular rheumatological diseases.
Topics: Administration, Cutaneous; Adult; Aged; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Fema | 1993 |
A controlled clinical study on the new topical dosage form of DHEP plasters in patients suffering from localized inflammatory diseases.
Topics: Administration, Cutaneous; Arthritis; Diclofenac; Female; Humans; Male; Middle Aged; Pain Measuremen | 1993 |
Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Cyclooxygenase 2; Cyclooxyg | 1999 |
Clinical response to etodolac in the management of pain.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Bursitis; Diclofenac; Eto | 1990 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.
Topics: Administration, Oral; Diclofenac; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged | 1990 |
11 other studies available for diclofenac and Tendinitis
| Article | Year |
|---|---|
A case of calcific retropharyngeal tendinitis: the significance of an early diagnosis.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcinosis; Cervical Verte | 2013 |
Analysis of the effect of phototherapy in model with traumatic Achilles tendon injury in rats.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Collagen | 2014 |
The low level laser therapy (LLLT) operating in 660 nm reduce gene expression of inflammatory mediators in the experimental model of collagenase-induced rat tendinitis.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagenases; Cyclooxygenase 2; D | 2015 |
Inflammatory cytokines content in Achilles tendinopathy after phonophoresis treatment combined with gold nanoparticles and diclophenac diethylammonium in rats.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents; Diclofenac; Disease Models, Animal; Gold; Inflam | 2015 |
[Neck pain due to tendonitis of the longus colli muscle].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Calcinosis; Diclofenac; Female; Humans; Magnetic Reso | 2010 |
Gold nanoparticles and diclofenac diethylammonium administered by iontophoresis reduce inflammatory cytokines expression in Achilles tendinitis.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Diclofenac; Disease Mo | 2012 |
Low-level laser therapy in collagenase-induced Achilles tendinitis in rats: analyses of biochemical and biomechanical aspects.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biochemistry; Biomechanical Pheno | 2012 |
A case of calcific retropharyngeal tendinitis suspected to be a retropharyngeal abscess upon the first medical examination.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Fine-Needle; Calcinosis; Dexamethasone; Diag | 2006 |
[After taking non-steroidal anti-inflammatory agents. What is the cause of the "blue spot?" ].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diclofenac; Dose-Response Re | 2007 |
[Panmyelopathy after administration of diclofenac?].
Topics: Adolescent; Adult; Bone Marrow Diseases; Diclofenac; Female; Humans; Male; Phenylacetates; Rheumatic | 1979 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; | 1985 |