Page last updated: 2024-10-26

diclofenac and Strabismus

diclofenac has been researched along with Strabismus in 11 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the comparative effects and safety of topical diclofenac sodium, fluorometholone, and dexamethasone for controlling inflammation after routine strabismus surgery."9.27A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery. ( Bae, S; Choi, DC; Choi, DG; Kim, J; Lee, JY, 2018)
"This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery."9.08Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995)
"Forty children undergoing strabismus surgery as day patients were randomly allocated to receive oxybuprocaine 0."9.08Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery. ( Benham, SW; Lawson, RA; McNicol, LR; Morton, NS, 1997)
"Diclofenac appears to be as effective as betamethasone in controlling postoperative inflammation following strabismus surgery and may offer a safer alternative to the use of topical steroids."9.08Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery. ( Butt, Z; Fleck, B; McIlwaine, G; Wright, M, 1997)
"The diclofenac- and prednisolone-treated eyes were compared on postoperative days 3 and 7 with respect to signs of inflammation (e."9.08A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. ( Apt, L; Isenberg, SJ; Voo, I, 1998)
" Nonsteroidal anti-inflammatory drugs, including diclofenac sodium, are inflammation suppressive drugs that may modulate wound healing, including postoperative inflammation."8.31Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits. ( Bani, AP; La Distia Nora, R; Putera, I; Susanto, E, 2023)
"Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)."6.68Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997)
"To evaluate the comparative effects and safety of topical diclofenac sodium, fluorometholone, and dexamethasone for controlling inflammation after routine strabismus surgery."5.27A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery. ( Bae, S; Choi, DC; Choi, DG; Kim, J; Lee, JY, 2018)
"This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery."5.08Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995)
"Forty children undergoing strabismus surgery as day patients were randomly allocated to receive oxybuprocaine 0."5.08Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery. ( Benham, SW; Lawson, RA; McNicol, LR; Morton, NS, 1997)
"Diclofenac appears to be as effective as betamethasone in controlling postoperative inflammation following strabismus surgery and may offer a safer alternative to the use of topical steroids."5.08Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery. ( Butt, Z; Fleck, B; McIlwaine, G; Wright, M, 1997)
"The diclofenac- and prednisolone-treated eyes were compared on postoperative days 3 and 7 with respect to signs of inflammation (e."5.08A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. ( Apt, L; Isenberg, SJ; Voo, I, 1998)
" Nonsteroidal anti-inflammatory drugs, including diclofenac sodium, are inflammation suppressive drugs that may modulate wound healing, including postoperative inflammation."4.31Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits. ( Bani, AP; La Distia Nora, R; Putera, I; Susanto, E, 2023)
"Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)."2.68Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Bani, AP2
Putera, I2
Susanto, E2
La Distia Nora, R2
Kim, J1
Choi, DC1
Bae, S1
Choi, DG1
Lee, JY1
Akyol-Salman, I1
Leçe-Sertöz, D1
Baykal, O1
Mikawa, K2
Nishina, K2
Maekawa, N2
Asano, M1
Obara, H2
Shiga, M1
Morton, NS1
Benham, SW1
Lawson, RA1
McNicol, LR1
Wright, M1
Butt, Z1
McIlwaine, G1
Fleck, B1
Apt, L1
Voo, I1
Isenberg, SJ1
Helveston, EM1
Snir, M1
Axer-Siegel, R1
Friling, R1
Weinberger, D1
Wennström, B1
Reinsfelt, B1

Trials

9 trials available for diclofenac and Strabismus

ArticleYear
A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2018, Volume: 34, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Child; Dexamethasone; Diclofenac; Female; Fluorometholon

2018
Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Ch

2007
Oral clonidine premedication reduces vomiting in children after strabismus surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:11

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anti-Inflammatory Agents, N

1995
Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:1

    Topics: Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Inflammatory Agents, Non-Steroidal

1997
Diclofenac vs oxybuprocaine eyedrops for analgesia in paediatric strabismus surgery.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:3

    Topics: Ambulatory Surgical Procedures; Analgesia; Anesthesia, General; Anesthetics, Local; Anti-Inflammator

1997
Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery.
    The British journal of ophthalmology, 1997, Volume: 81, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Child; Child, Prescho

1997
A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery.
    Ophthalmology, 1998, Volume: 105, Issue:8

    Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroid

1998
Efficacy of diclofenac versus dexamethasone for treatment after strabismus surgery.
    Ophthalmology, 2000, Volume: 107, Issue:10

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Prescho

2000
Rectally administered diclofenac (Voltaren) reduces vomiting compared with opioid (morphine) after strabismus surgery in children.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:4

    Topics: Administration, Rectal; Adolescent; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflamm

2002

Other Studies

2 other studies available for diclofenac and Strabismus

ArticleYear
Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits.
    Current eye research, 2023, Volume: 48, Issue:3

    Topics: Actins; Administration, Topical; Animals; Diclofenac; Inflammation; Muscle, Smooth; Rabbits; Strabis

2023
Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits.
    Current eye research, 2023, Volume: 48, Issue:3

    Topics: Actins; Administration, Topical; Animals; Diclofenac; Inflammation; Muscle, Smooth; Rabbits; Strabis

2023
Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits.
    Current eye research, 2023, Volume: 48, Issue:3

    Topics: Actins; Administration, Topical; Animals; Diclofenac; Inflammation; Muscle, Smooth; Rabbits; Strabis

2023
Comparative Assessment of Short-Term Tendon-Scleral Postoperative Inflammation and α-Smooth Muscle Actin Expression following Oral and Topical Diclofenac Administration for Strabismus Surgery in Rabbits.
    Current eye research, 2023, Volume: 48, Issue:3

    Topics: Actins; Administration, Topical; Animals; Diclofenac; Inflammation; Muscle, Smooth; Rabbits; Strabis

2023
Topical steroids not 'standard of care'.
    Binocular vision & strabismus quarterly, 1998, Volume: 13, Issue:2

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Delivery of Health Care; Di

1998