diclofenac has been researched along with Sprains in 21 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "According to these results, diclofenac and paracetamol had the same effect on pain reduction of ankle sprains but more acute ankle edema was present in patients who were treated with diclofenac than in patients who were treated with paracetamol." | 9.15 | Efficacy of paracetamol versus diclofenac for Grade II ankle sprains. ( Lyrtzis, C; Natsis, K; Noussios, G; Papadopoulos, C; Papathanasiou, E, 2011) |
| "It was concluded that diclofenac sodium and paracetamol are effective and well tolerated as a short term treatment alternatives for acute ankle injuries." | 9.12 | The efficacy of paracetamol in the treatment of ankle sprains in comparison with diclofenac sodium. ( Agus, H; Kayali, C; Surer, L; Turgut, A, 2007) |
| "A previously published study comparing the efficacy of comfrey extract to a commercial diclofenac (CAS 78213-16-8) preparation in the treatment of unilateral ankle sprains is critically re-evaluated." | 9.12 | Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). ( Bulitta, M; D'Anchise, R; Giannetti, B, 2007) |
| "Many types of acute pain have been managed with traditional oral non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase-2 inhibitors (coxibs)." | 6.46 | Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury. ( Argoff, CE; McCarberg, BH, 2010) |
| "Diclofenac 4% spray gel rapidly relieves pain and improves mobility in patients with acute, uncomplicated ankle sprain and is well tolerated." | 5.17 | A randomized, double-blind, placebo-controlled multicentre study to evaluate the efficacy and safety of diclofenac 4% spray gel in the treatment of acute uncomplicated ankle sprain. ( Giannetti, B; Menke, G; Novellini, R; Predel, HG; Seigfried, B, 2013) |
| "According to these results, diclofenac and paracetamol had the same effect on pain reduction of ankle sprains but more acute ankle edema was present in patients who were treated with diclofenac than in patients who were treated with paracetamol." | 5.15 | Efficacy of paracetamol versus diclofenac for Grade II ankle sprains. ( Lyrtzis, C; Natsis, K; Noussios, G; Papadopoulos, C; Papathanasiou, E, 2011) |
| " The efficacy and tolerability of a novel plaster containing both diclofenac epolamine (DHEP) and heparin in the treatment of acute painful ankle sprains with oedema was investigated in a randomized, double-blind, placebo-controlled study." | 5.14 | Effect of a plaster containing DHEP and heparin in acute ankle sprains with oedema: a randomized, double-blind, placebo-controlled, clinical study. ( Coudreuse, JM; de Vathaire, F, 2010) |
| "Celecoxib, a COX-2 selective inhibitor, is as effective as diclofenac SR in treating ankle sprains." | 5.12 | Efficacy and tolerability of celecoxib compared with diclofenac slow release in the treatment of acute ankle sprain in an Asian population. ( Abrahan, L; Fakir-Bolte, C; Hwang, LJ; Lau, FL; Nadarajah, A, 2006) |
| "It was concluded that diclofenac sodium and paracetamol are effective and well tolerated as a short term treatment alternatives for acute ankle injuries." | 5.12 | The efficacy of paracetamol in the treatment of ankle sprains in comparison with diclofenac sodium. ( Agus, H; Kayali, C; Surer, L; Turgut, A, 2007) |
| "A previously published study comparing the efficacy of comfrey extract to a commercial diclofenac (CAS 78213-16-8) preparation in the treatment of unilateral ankle sprains is critically re-evaluated." | 5.12 | Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). ( Bulitta, M; D'Anchise, R; Giannetti, B, 2007) |
| " Local adverse events were minimum for both groups." | 2.67 | Single blind study to evaluate the efficacy and safety of naproxen gel compared with diclophenac emulgel in the treatment of soft tissue injuries. ( Butrón, F; Galicia, A; Martinez-Zurita, F; Zamora, G, 1994) |
| "Many types of acute pain have been managed with traditional oral non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase-2 inhibitors (coxibs)." | 2.46 | Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury. ( Argoff, CE; McCarberg, BH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Predel, HG | 3 |
| Giannetti, B | 4 |
| Seigfried, B | 1 |
| Novellini, R | 1 |
| Menke, G | 1 |
| Yanchick, J | 1 |
| Magelli, M | 1 |
| Bodie, J | 1 |
| Sjogren, J | 1 |
| Rovati, S | 2 |
| McCarberg, BH | 1 |
| Argoff, CE | 1 |
| Klainguti, A | 1 |
| Forgacs, A | 1 |
| Berkes, I | 1 |
| Castellacci, E | 1 |
| Coudreuse, JM | 1 |
| de Vathaire, F | 1 |
| Costantino, C | 1 |
| Kwarecki, J | 1 |
| Samokhin, AV | 1 |
| Mautone, G | 2 |
| Center, DM | 1 |
| Migliorino, R | 1 |
| Lyrtzis, C | 1 |
| Natsis, K | 1 |
| Papadopoulos, C | 1 |
| Noussios, G | 1 |
| Papathanasiou, E | 1 |
| Hamelsky, S | 1 |
| Gold, M | 1 |
| Mahler, P | 1 |
| Mahler, F | 1 |
| Duruz, H | 1 |
| Ramazzina, M | 1 |
| Liguori, V | 1 |
| Solignac, M | 1 |
| Koll, R | 1 |
| Bulitta, M | 2 |
| Staiger, C | 1 |
| Nadarajah, A | 1 |
| Abrahan, L | 1 |
| Lau, FL | 1 |
| Hwang, LJ | 1 |
| Fakir-Bolte, C | 1 |
| Kayali, C | 1 |
| Agus, H | 1 |
| Surer, L | 1 |
| Turgut, A | 1 |
| D'Anchise, R | 1 |
| Böhmer, D | 1 |
| Ambrus, P | 1 |
| Butrón, F | 1 |
| Galicia, A | 1 |
| Zamora, G | 1 |
| Martinez-Zurita, F | 1 |
| Morán, M | 1 |
| Diebschlag, W | 1 |
| Machtey, I | 1 |
2 reviews available for diclofenac and Sprains
| Article | Year |
|---|---|
Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Contusions; Diclofenac; Humans; Pain; Soft Tiss | 2010 |
[Assessment of a topical NSAIDs in the treatment of pain and inflammation. The example of Flector Plaster, a local bioadhesive plaster containing diclofenac epolamine].
Topics: Administration, Topical; Animals; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Athletic | 2004 |
15 trials available for diclofenac and Sprains
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled multicentre study to evaluate the efficacy and safety of diclofenac 4% spray gel in the treatment of acute uncomplicated ankle sprain.
Topics: Acute Disease; Administration, Topical; Adult; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroid | 2013 |
A plaster containing DHEP and heparin for mild to moderate contusions and sprains with haematoma: a double-blind randomized study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2010 |
Effect of a plaster containing DHEP and heparin in acute ankle sprains with oedema: a randomized, double-blind, placebo-controlled, clinical study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Ankle Injuries; Anti-Inflammatory Agents, Non-Ster | 2010 |
Diclofenac epolamine plus heparin plaster versus diclofenac epolamine plaster in mild to moderate ankle sprain: a randomized, double-blind, parallel-group, placebo-controlled, multicentre, phase III trial.
Topics: Adolescent; Adult; Aged; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Di | 2011 |
Efficacy of paracetamol versus diclofenac for Grade II ankle sprains.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Ankle Injuries; Anti-Inflammatory Agents | 2011 |
Efficacy and safety of diclofenac diethylamine 2.32% gel in acute ankle sprain.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Ankle Injuries; Diclofenac; Dou | 2012 |
Double-blind, randomized, controlled study on the efficacy and safety of a novel diclofenac epolamine gel formulated with lecithin for the treatment of sprains, strains and contusions.
Topics: Acetaminophen; Administration, Topical; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ankle Inj | 2003 |
Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.
Topics: Adolescent; Adult; Ankle Injuries; Area Under Curve; Comfrey; Diclofenac; Female; Gels; Humans; Male | 2005 |
Efficacy and tolerability of celecoxib compared with diclofenac slow release in the treatment of acute ankle sprain in an Asian population.
Topics: Acute Disease; Adult; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Asia; Blood Platelets | 2006 |
The efficacy of paracetamol in the treatment of ankle sprains in comparison with diclofenac sodium.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroi | 2007 |
Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions).
Topics: Acute Disease; Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under C | 2007 |
[Treatment of muscular injuries with diclofenac-diethylammonium emulsion gel].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Contusio | 1995 |
Single blind study to evaluate the efficacy and safety of naproxen gel compared with diclophenac emulgel in the treatment of soft tissue injuries.
Topics: Adult; Contusions; Diclofenac; Edema; Female; Gels; Humans; Male; Middle Aged; Naproxen; Pain Measur | 1994 |
An observer-blind comparison of diclofenac potassium, piroxicam and placebo in the treatment of ankle sprains.
Topics: Adult; Ankle Injuries; Diclofenac; Female; Humans; Male; Middle Aged; Pain; Piroxicam; Single-Blind | 1990 |
[Diclofenac in blunt traumatic ankle joint swelling. Volumetric monitoring in a placebo controlled double-blind trial].
Topics: Adolescent; Adult; Ankle Injuries; Athletic Injuries; Clinical Trials as Topic; Contusions; Diclofen | 1986 |
4 other studies available for diclofenac and Sprains
| Article | Year |
|---|---|
Time to significant pain reduction following DETP application vs placebo for acute soft tissue injuries.
Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Ankle Joint; Anti-Inflammatory Agen | 2010 |
Topical diclofenac for sprains? These doctors say No.
Topics: Administration, Topical; Ankle Injuries; Cyclooxygenase Inhibitors; Diclofenac; Humans; Sprains and | 2011 |
[Naturopathy approaches in sports medicine. Rapid recovery of performance capability].
Topics: Administration, Topical; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; | 2012 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; | 1985 |