diclofenac has been researched along with Shock, Septic in 7 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of cyclo-oxygenase pathway inhibition by diclofenac on the endotoxin shock response and ET-1 turnover, were investigated in five groups of pigs." | 7.69 | Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig. ( Lundberg, JM; Rudehill, A; Weitzberg, E, 1995) |
| "To prevent endotoxin-induced pulmonary hypertension in the pig with a combination of a nonpeptide mixed endothelin receptor antagonist, bosentan, and a cyclooxygenase inhibitor, diclofenac." | 7.69 | The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock. ( Hemsén, A; Lundberg, JM; Rudehill, A; Wanecek, M; Weitzberg, E, 1997) |
| " The effects of cyclo-oxygenase pathway inhibition by diclofenac on the endotoxin shock response and ET-1 turnover, were investigated in five groups of pigs." | 3.69 | Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig. ( Lundberg, JM; Rudehill, A; Weitzberg, E, 1995) |
| "To prevent endotoxin-induced pulmonary hypertension in the pig with a combination of a nonpeptide mixed endothelin receptor antagonist, bosentan, and a cyclooxygenase inhibitor, diclofenac." | 3.69 | The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock. ( Hemsén, A; Lundberg, JM; Rudehill, A; Wanecek, M; Weitzberg, E, 1997) |
| "Using the endotoxin shock model in mongrel dogs, the effects of a cyclooxygenase antagonist (diclofenac sodium) and an antihistamine (chlorpheniramine) were evaluated." | 3.67 | Inhibition of vasoactive substances in experimental endotoxin shock. ( Cruz, NI; Lowry, PC; O'Neil, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Orlando, A | 1 |
| Marrone, C | 1 |
| Nicoli, N | 1 |
| Tamburello, G | 1 |
| Rizzo, A | 1 |
| Pagliaro, L | 1 |
| Cottone, M | 1 |
| D'Amico, G | 1 |
| Li, L | 1 |
| Rossoni, G | 1 |
| Sparatore, A | 1 |
| Lee, LC | 1 |
| Del Soldato, P | 1 |
| Moore, PK | 1 |
| Weitzberg, E | 2 |
| Lundberg, JM | 2 |
| Rudehill, A | 2 |
| Mózes, T | 1 |
| Heiligers, JP | 1 |
| Tak, CJ | 1 |
| Zijlstra, FJ | 1 |
| Ben-Efraim, S | 1 |
| Saxena, PR | 1 |
| Bonta, IL | 1 |
| Wanecek, M | 1 |
| Hemsén, A | 1 |
| Kortelainen, ML | 1 |
| Särkioja, T | 1 |
| O'Neil, J | 1 |
| Lowry, PC | 1 |
| Cruz, NI | 1 |
7 other studies available for diclofenac and Shock, Septic
| Article | Year |
|---|---|
Fatal necrotising fasciitis associated with intramuscular injection of nonsteroidal anti-inflammatory drugs after uncomplicated endoscopic polypectomy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Buttocks; Diclofenac; Endoscopy; Fasciitis, Necrotizing; Fa | 2007 |
Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Diclofenac; Drug Evaluation, Preclinical; Gastroi | 2007 |
Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Diclofenac; E | 1995 |
Protective effect of diclofenac sodium against endotoxic shock in anaesthetized pigs.
Topics: Animals; Blood Cell Count; Blood Glucose; Diclofenac; Eicosanoids; Female; Hemodynamics; Hemoglobins | 1993 |
The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock.
Topics: Animals; Bosentan; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Endothelin Rece | 1997 |
Fatal complications of intramuscular and intra-articular injections.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Brain Damage, Chronic; Cause of Death; Chlorp | 1990 |
Inhibition of vasoactive substances in experimental endotoxin shock.
Topics: Animals; Chlorpheniramine; Diclofenac; Dogs; Drug Therapy, Combination; Shock, Septic | 1986 |