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diclofenac and Scleroderma, Systemic

diclofenac has been researched along with Scleroderma, Systemic in 4 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research Excerpts

ExcerptRelevanceReference
"We describe a patient with scleroderma who developed immune thrombocytopenia secondary to diclofenac on 2 occasions."7.68Diclofenac induced immune thrombocytopenia. ( Epstein, M; Stein, H; Vickars, L, 1990)
"We describe a patient with scleroderma who developed immune thrombocytopenia secondary to diclofenac on 2 occasions."3.68Diclofenac induced immune thrombocytopenia. ( Epstein, M; Stein, H; Vickars, L, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Jiang, BE1
Jiang, X1
Zhang, Q1
Liang, Q1
Qiu, ZL1
Sun, XB1
Yang, JJ1
Chen, S1
Yi, C1
Chai, X1
Liu, M1
Yu, LF1
Lu, W1
Zhang, HK1
Richard, V1
Solans, V1
Favre, J1
Henry, JP1
Lallemand, F1
Thuillez, C1
Marie, I1
Epstein, M1
Vickars, L1
Stein, H1
Kagan, A1
Nissim, F1
Green, L1
Bar-Khayim, Y1

Reviews

1 review available for diclofenac and Scleroderma, Systemic

ArticleYear
Scleroderma renal crisis without hypertension.
    The Journal of rheumatology, 1989, Volume: 16, Issue:5

    Topics: Acute Kidney Injury; Diclofenac; Female; Humans; Middle Aged; Scleroderma, Systemic

1989

Other Studies

3 other studies available for diclofenac and Scleroderma, Systemic

ArticleYear
From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis.
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Designer Drugs; Drug Discovery; Humans; Receptor, Cannabinoid, CB2; Scleroderma, Systemic; Structure

2021
Role of endogenous endothelin in endothelial dysfunction in murine model of systemic sclerosis: tight skin mice 1.
    Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:6

    Topics: Acetylcholine; Animals; Bosentan; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dos

2008
Diclofenac induced immune thrombocytopenia.
    The Journal of rheumatology, 1990, Volume: 17, Issue:10

    Topics: Diclofenac; Humans; Immune System Diseases; Male; Middle Aged; Platelet Count; Prednisone; Scleroder

1990