diclofenac has been researched along with Rheumatic Diseases in 81 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Rheumatic Diseases: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to explore the effect of geranylgeranylacetone on small-intestinal mucosal injuries induced by diclofenac sodium in patients with rheumatic diseases." | 9.20 | Geranylgeranylacetone protects against small-intestinal injuries induced by diclofenac in patients with rheumatic diseases: a prospective randomized study. ( Chen, M; Huang, X; Li, L; Liang, L; Xiong, L; Yang, X; Ye, Y; Zhan, Z, 2015) |
| "In a randomized, double-blind comparative study involving a total of 1630 outpatients, tenoxicam, a new nonsteroidal anti-inflammatory drug belonging to the oxicam group, piroxicam and diclofenac retard were tested for their efficacy und tolerability in the treatment of osteoarthritis and extra-articular rheumatism." | 9.06 | [Double-blind randomized multicenter study with tenoxicam, piroxicam and diclofenac sodium retard in the treatment of ambulatory patients with arthroses and soft tissue rheumatism]. ( Gobelet, CA; Moser, U; Schwarz, HA; Waldburger, M, 1989) |
| "150 mg/day sodic diclofenac was found particularly active in subjects with diathetic rheumatism and arthrosis." | 9.04 | [Experiences with the use of sodium diclofenac (Voltaren) in rheumatic diseases]. ( Durante, F, 1978) |
| "Trials of 2 to 6 months' duration have shown aceclofenac to be an effective agent in the management of pain and rheumatic disease." | 8.81 | Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease. ( Dooley, M; Dunn, CJ; Spencer, CM, 2001) |
| "Diclofenac sodium, a phenylacetic acid derivative, is a non-steroidal, anti-inflammatory, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and allied conditions, and in the treatment of pain resulting from minor surgery, trauma and dysmenorrhoea." | 8.76 | Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| "Celecoxib significantly increased the incidence of new onset hypertension in this cohort of Indian patients with rheumatic diseases." | 7.79 | How safe is Celecoxib for Asian-Indian patients with rheumatic diseases? ( Chandra, C; Chandy, SJ; Danda, D; Iliyas, MM; Mathew, AJ, 2013) |
| " The non-steroidal anti-inflammatory drug diclofenacsodium (Voltaren) did not significantly influence the demethylation of 14C-aminopyrine in 5 patients with rheumatic diseases and in 2 healthy probands." | 7.66 | [Experiences with the 14C-aminopyrine breath test in liver cirrhosis and under the effect of sodium diclofenac (Voltaren)]. ( Eitner, K; Hippius, M; Krombholz, B; Reinicke, C; Stiller, KJ; Wächter, G, 1983) |
| "In a double-blind study, diclofenac sodium (Voltaren)--administered for 14 days in a dosage of 25 mg t." | 6.64 | A comparative short-term trial with Voltaren (diclofenac sodium) and naproxen in soft-tissue rheumatism. ( Valtonen, EJ, 1978) |
| "Aceclofenac is a phenylacetic acid derivative with anti-inflammatory and analgesic properties similar to those of diclofenac." | 6.39 | Aceclofenac. A review of its pharmacodynamic properties and therapeutic potential in the treatment of rheumatic disorders and in pain management. ( Brogden, RN; Wiseman, LR, 1996) |
| " This results in an increase in the rate of absorption of the active compound and, consequently, in an earlier onset of analgesic action." | 6.38 | Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease. ( Franchimont, P; Reginster, JY, 1993) |
| "Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions." | 6.16 | Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Sorkin, EM; Todd, PA, 1988) |
| "We aimed to explore the effect of geranylgeranylacetone on small-intestinal mucosal injuries induced by diclofenac sodium in patients with rheumatic diseases." | 5.20 | Geranylgeranylacetone protects against small-intestinal injuries induced by diclofenac in patients with rheumatic diseases: a prospective randomized study. ( Chen, M; Huang, X; Li, L; Liang, L; Xiong, L; Yang, X; Ye, Y; Zhan, Z, 2015) |
| "In a randomized, double-blind comparative study involving a total of 1630 outpatients, tenoxicam, a new nonsteroidal anti-inflammatory drug belonging to the oxicam group, piroxicam and diclofenac retard were tested for their efficacy und tolerability in the treatment of osteoarthritis and extra-articular rheumatism." | 5.06 | [Double-blind randomized multicenter study with tenoxicam, piroxicam and diclofenac sodium retard in the treatment of ambulatory patients with arthroses and soft tissue rheumatism]. ( Gobelet, CA; Moser, U; Schwarz, HA; Waldburger, M, 1989) |
| "A double-blind randomized study was performed to compare ionization with diclofenac sodium (150 mg) and ionization with saline solution in two groups of patients with scapulo-humeral periarthritis or elbow epicondylitis." | 5.05 | Ionization with diclofenac sodium in rheumatic disorders: a double-blind placebo-controlled trial. ( Grossi, E; Vecchini, L, 1984) |
| "150 mg/day sodic diclofenac was found particularly active in subjects with diathetic rheumatism and arthrosis." | 5.04 | [Experiences with the use of sodium diclofenac (Voltaren) in rheumatic diseases]. ( Durante, F, 1978) |
| "Trials of 2 to 6 months' duration have shown aceclofenac to be an effective agent in the management of pain and rheumatic disease." | 4.81 | Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease. ( Dooley, M; Dunn, CJ; Spencer, CM, 2001) |
| "A study of individual response factors to the anti-inflammatory drug Diclofenac, as carried out in 3,123 patients, selected by 200 french rheumatism specialists." | 4.77 | [Individual variation in the response to non-steroidal anti-inflammatory agents]. ( Gérard, MJ, 1988) |
| "Diclofenac sodium, a phenylacetic acid derivative, is a non-steroidal, anti-inflammatory, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and allied conditions, and in the treatment of pain resulting from minor surgery, trauma and dysmenorrhoea." | 4.76 | Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| "Celecoxib significantly increased the incidence of new onset hypertension in this cohort of Indian patients with rheumatic diseases." | 3.79 | How safe is Celecoxib for Asian-Indian patients with rheumatic diseases? ( Chandra, C; Chandy, SJ; Danda, D; Iliyas, MM; Mathew, AJ, 2013) |
| "To simultaneously assess the short-term reduction in risk of gastrointestinal (GI) complications and increase in risk of acute myocardial infarction (MI) by celecoxib compared with rofecoxib and several nonselective nonsteroidal antiinflammatory drugs (NSAIDs) using instrumental variable analysis." | 3.73 | Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis. ( Brookhart, MA; Rassen, J; Schneeweiss, S; Solomon, DH; Wang, PS, 2006) |
| "During a post-marketing surveillance study, 641 patients (age range 18 to 86 years) with painful rheumatic diseases, mostly of vertebral etiology, were given ready-for-use infusions containing a combination of the non-steroid antiphlogistic agent diclofenac (75 mg) and the muscle relaxing agent orphenadrine (30 mg) parenterally for 7 days." | 3.70 | [Results of efficacy study with diclofenac/orphenadrine infusions in patients with musculoskeletal diseases and functional disorders]. ( Aglas, F; Chlud, K; Fruhwald, FM, 1998) |
| " The non-steroidal anti-inflammatory drug diclofenacsodium (Voltaren) did not significantly influence the demethylation of 14C-aminopyrine in 5 patients with rheumatic diseases and in 2 healthy probands." | 3.66 | [Experiences with the 14C-aminopyrine breath test in liver cirrhosis and under the effect of sodium diclofenac (Voltaren)]. ( Eitner, K; Hippius, M; Krombholz, B; Reinicke, C; Stiller, KJ; Wächter, G, 1983) |
| "A rapid method for the estimation of sodium-(o-[(2,6-dichlorophenyl)-amino]-phenyl)-acetate (diclofenac-Na, Voltaren) used in the treatment of rheumatic diseases, in human blood plasma is described." | 3.65 | Quantitative determination of sodium-o-[(2,6-dichlorophenyl)-amino]phenylacetate (diclofenac) in human blood plasma or serum. ( Brombacher, PJ; Cremers, HM; Quanjel-Schreurs, RA; Verheesen, PE, 1977) |
| "Dexibuprofen showed a lower rate of gastroduodenal and intestinal mucosal injury." | 2.72 | Modification of pepsinogen I levels and their correlation with gastrointestinal injury after administration of dexibuprofen, ibuprofen or diclofenac: a randomized, open-label, controlled clinical trial. ( Blasco, M; Caunedo, A; Esteban, J; Gómez, BJ; Hergueta, P; Herrerías, JM; Pellicer, FJ; Redondo, L; Rodríguez-Téllez, M; Romero, R; Sáenz-Dana, M, 2006) |
| " Adverse experiences were infrequent and generally mild or transient." | 2.66 | Worldwide clinical safety experience with diclofenac. ( Willkens, RF, 1985) |
| "In a double-blind study, diclofenac sodium (Voltaren)--administered for 14 days in a dosage of 25 mg t." | 2.64 | A comparative short-term trial with Voltaren (diclofenac sodium) and naproxen in soft-tissue rheumatism. ( Valtonen, EJ, 1978) |
| "Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints." | 2.49 | Comfrey root: from tradition to modern clinical trials. ( Staiger, C, 2013) |
| " Traditional NSAIDs are associated with an increased risk of serious gastrointestinal (GI) adverse events versus COX-2 selective inhibitors, and chronic use frequently necessitates adjunctive therapy with gastroprotective agents." | 2.44 | Efficacy of the newest COX-2 selective inhibitors in rheumatic disease. ( Baraf, HS, 2007) |
| "Aceclofenac is a phenylacetic acid derivative with anti-inflammatory and analgesic properties similar to those of diclofenac." | 2.39 | Aceclofenac. A review of its pharmacodynamic properties and therapeutic potential in the treatment of rheumatic disorders and in pain management. ( Brogden, RN; Wiseman, LR, 1996) |
| " This results in an increase in the rate of absorption of the active compound and, consequently, in an earlier onset of analgesic action." | 2.38 | Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease. ( Franchimont, P; Reginster, JY, 1993) |
| " An ibuprofen dosage of 1,600 mg/day did not induce LUF syndrome either at continuous periovulatory or discontinuous exposure." | 1.37 | Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies. ( Micu, MC; Micu, R; Ostensen, M, 2011) |
| " This is due to the lower incidence of gastrointestinal adverse events with nimesulide, and the absence of serious gastrointestinal complications leading to hospitalization, which more than offset the higher acquisition cost of nimesulide." | 1.30 | Economic comparison of nimesulide and diclofenac, and the incidence of adverse events in the treatment of rheumatic disease in Greece. ( Liaropoulos, L, 1999) |
| "The costs of treating gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs) are shown to increase the total cost of NSAID treatment to the Assurance-Maladie, the French national health insurance system." | 1.28 | The economic consequences of NSAID-induced gastropathy: the French context. ( de Pouvourville, G, 1992) |
| "Meclofenamic acid is an analgesic endowed with anti-inflammatory properties." | 1.28 | Clinical experiences in the treatment of pain in rheumatology. ( Pellegrini, P, 1991) |
| " An evaluation of the response-related pharmacokinetic parameters of the three presently most widely used NSAID's, namely diclofenac, indomethacin and piroxicam shows some obvious reasons: While the onset of absorption and the bioavailability of diclofenac varies considerably, we find relevant differences in the terminal plasma half-life of indomethacin and particularly piroxicam." | 1.27 | Pharmacokinetic factors as causes of variability in response to non-steroidal anti-inflammatory drugs. ( Brune, K, 1985) |
| "Diclofenac (Voltarol) has no effect on carbohydrate metabolism, insulin levels or tolbutamide metabolism, nor does it enhance the effect of tolbutamide, biguanide or glibenclamide." | 1.26 | Diclofenac sodium (Voltarol): drug interactions and special studies. ( Fowler, PD, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (59.26) | 18.7374 |
| 1990's | 20 (24.69) | 18.2507 |
| 2000's | 9 (11.11) | 29.6817 |
| 2010's | 4 (4.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danda, D | 1 |
| Iliyas, MM | 1 |
| Chandy, SJ | 1 |
| Chandra, C | 1 |
| Mathew, AJ | 1 |
| Xiong, L | 1 |
| Huang, X | 1 |
| Li, L | 1 |
| Yang, X | 1 |
| Liang, L | 1 |
| Zhan, Z | 1 |
| Ye, Y | 1 |
| Chen, M | 1 |
| Micu, MC | 1 |
| Micu, R | 1 |
| Ostensen, M | 1 |
| Staiger, C | 1 |
| Nasonova, VA | 2 |
| Gómez, BJ | 1 |
| Caunedo, A | 1 |
| Redondo, L | 1 |
| Esteban, J | 1 |
| Sáenz-Dana, M | 1 |
| Blasco, M | 1 |
| Hergueta, P | 1 |
| Rodríguez-Téllez, M | 1 |
| Romero, R | 1 |
| Pellicer, FJ | 1 |
| Herrerías, JM | 1 |
| Schneeweiss, S | 1 |
| Solomon, DH | 1 |
| Wang, PS | 1 |
| Rassen, J | 1 |
| Brookhart, MA | 1 |
| Einecke, D | 1 |
| Baraf, HS | 1 |
| Polozov, KK | 1 |
| Domnikov, AD | 1 |
| Nikulova, MM | 1 |
| Gross, W | 1 |
| Kroh, J | 1 |
| Krebs, A | 1 |
| Zöller, H | 1 |
| Benvenuti, C | 1 |
| Guidoni, G | 1 |
| Longoni, A | 1 |
| Mordini, M | 1 |
| Al-Sharkawi, MS | 1 |
| Vecchini, L | 1 |
| Grossi, E | 1 |
| Reinicke, C | 1 |
| Eitner, K | 1 |
| Hippius, M | 1 |
| Krombholz, B | 1 |
| Stiller, KJ | 1 |
| Wächter, G | 2 |
| Wessel, H | 1 |
| Reinike, K | 1 |
| Schlumpf, U | 2 |
| Brogden, RN | 2 |
| Heel, RC | 1 |
| Pakes, GE | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Kanbarov, GM | 1 |
| Dzhuzenova, BS | 1 |
| Sørensen, K | 1 |
| Hørlyk, K | 1 |
| Jakobsen, K | 1 |
| Tanner, E | 1 |
| Lasarof, I | 1 |
| Gaida, P | 1 |
| Baroni, L | 1 |
| Comoglio, T | 1 |
| Trombetta, N | 1 |
| Cornelli, U | 1 |
| Sigidin, IaA | 1 |
| Murav'ev, IuV | 1 |
| Lebedeva, OI | 1 |
| Burtsev, VI | 1 |
| Rashchupkina, ZP | 1 |
| Krikunov, VP | 1 |
| Kuzin, AV | 1 |
| Nasonov, EL | 1 |
| Chichasova, NV | 1 |
| Reginster, JY | 1 |
| Franchimont, P | 1 |
| Galeazzi, M | 1 |
| Marcolongo, R | 3 |
| Bhatt, AD | 1 |
| Sane, SP | 1 |
| Vaidya, AB | 1 |
| Bolar, HV | 1 |
| Wiseman, LR | 1 |
| de Paulis, A | 1 |
| Ciccarelli, A | 1 |
| Marinò, I | 1 |
| de Crescenzo, G | 1 |
| Marinò, D | 1 |
| Marone, G | 1 |
| Martens, M | 1 |
| Shield, MJ | 1 |
| Bianchi Porro, G | 1 |
| Lazzaroni, M | 1 |
| Petrillo, M | 1 |
| Manzionna, G | 1 |
| Montrone, F | 1 |
| Caruso, I | 1 |
| Aglas, F | 1 |
| Fruhwald, FM | 1 |
| Chlud, K | 1 |
| Liaropoulos, L | 1 |
| Fioravanti, A | 2 |
| Cicero, MR | 1 |
| Nerucci, F | 1 |
| Manopulo, R | 1 |
| Patel, BR | 1 |
| Dooley, M | 1 |
| Spencer, CM | 1 |
| Dunn, CJ | 1 |
| Pappalardo, A | 1 |
| Pulizzi, C | 1 |
| Mantia, S | 1 |
| Olah, J | 1 |
| Meyer, W | 1 |
| Bruck, S | 1 |
| Brombacher, PJ | 1 |
| Cremers, HM | 1 |
| Verheesen, PE | 1 |
| Quanjel-Schreurs, RA | 1 |
| Volle, L | 1 |
| Domenach, M | 1 |
| Tsvetkova, ES | 2 |
| Trofimova, TM | 1 |
| Peltier, AP | 1 |
| Rivet, JP | 1 |
| Søorensen, K | 1 |
| Nicoletti, B | 1 |
| Mignemi, G | 1 |
| Porzsolt, F | 1 |
| Heit, W | 1 |
| Heimpel, H | 1 |
| Asbeck, F | 1 |
| Aylward, M | 1 |
| Fowler, PD | 2 |
| John, V | 1 |
| Maddock, J | 1 |
| Seldrup, J | 1 |
| Foulon, J | 1 |
| Milić, D | 1 |
| Goch, JH | 1 |
| Adamska-Dyniewska, H | 1 |
| Dürrigl, T | 1 |
| Pucar, I | 1 |
| Durante, F | 1 |
| Valtonen, EJ | 1 |
| Ciccolunghi, SN | 2 |
| Chaudri, HA | 2 |
| Schubiger, BI | 2 |
| Reddrop, R | 1 |
| Fomina, AA | 1 |
| Mironova, KA | 1 |
| Klimovich, MD | 1 |
| de Pouvourville, G | 1 |
| Bach, GL | 1 |
| Knill-Jones, RP | 1 |
| Jajić, I | 2 |
| Jajić, Z | 1 |
| Pellegrini, P | 1 |
| Rechziegler, H | 1 |
| Thebud-Lassak, R | 1 |
| Moser, U | 1 |
| Waldburger, M | 1 |
| Schwarz, HA | 1 |
| Gobelet, CA | 1 |
| Ogle, C | 1 |
| Gérard, MJ | 1 |
| Todd, PA | 1 |
| Sorkin, EM | 1 |
| Russell, JG | 1 |
| Brune, K | 1 |
| Needs, CJ | 1 |
| Brooks, PM | 1 |
| Willkens, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Preventive and Treatment Effects of Hp Eradication and Teprenone in Patients Taking NSAIDs[NCT01547559] | 369 participants (Actual) | Interventional | 2007-06-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for diclofenac and Rheumatic Diseases
| Article | Year |
|---|---|
Comfrey root: from tradition to modern clinical trials.
Topics: Adult; Anti-Inflammatory Agents; Back Pain; Child; Child, Preschool; Comfrey; Diclofenac; Drug Combi | 2013 |
[Aceclofenac (aertal) in rheumatological practice].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Diclofenac; Humans; Rheumatic Disease | 2005 |
Efficacy of the newest COX-2 selective inhibitors in rheumatic disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Cardiovascular Dis | 2007 |
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interact | 1980 |
Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease.
Topics: Acute Disease; Adult; beta-Cyclodextrins; Controlled Clinical Trials as Topic; Cyclodextrins; Diclof | 1993 |
Aceclofenac. A review of its pharmacodynamic properties and therapeutic potential in the treatment of rheumatic disorders and in pain management.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Humans; Pain | 1996 |
Diclofenac/misoprostol: novel findings and their clinical potential.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Drug Synergism; Hemoglobins; | 1998 |
Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage Oligomeric Matrix Protein; Diclofenac; D | 2001 |
[Voltaren--1 new non-steroidal antirheumatic drug. Review of literature].
Topics: Aged; Diclofenac; Female; Humans; Male; Middle Aged; Phenylacetates; Rheumatic Diseases | 1977 |
The economic consequences of NSAID-induced gastropathy in the United Kingdom and commentary on the article by G. de Pouvourville.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Drug Combinations; Gastrointes | 1992 |
[Clinical profile of acemetacin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Indomethacin; Rand | 1990 |
[Individual variation in the response to non-steroidal anti-inflammatory agents].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Evaluation; Female; Humans; M | 1988 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
Antirheumatic medication during lactation.
Topics: Anti-Inflammatory Agents; Aspirin; Breast Feeding; Diclofenac; Female; Half-Life; Humans; Indoleacet | 1985 |
30 trials available for diclofenac and Rheumatic Diseases
| Article | Year |
|---|---|
Geranylgeranylacetone protects against small-intestinal injuries induced by diclofenac in patients with rheumatic diseases: a prospective randomized study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Diclofenac; Di | 2015 |
Modification of pepsinogen I levels and their correlation with gastrointestinal injury after administration of dexibuprofen, ibuprofen or diclofenac: a randomized, open-label, controlled clinical trial.
Topics: Administration, Oral; Adult; Cyclooxygenase Inhibitors; Diclofenac; Endoscopy, Gastrointestinal; Fem | 2006 |
Controlled study on flurbiprofen and diclofenac in the treatment of rheumatic disorders.
Topics: Clinical Trials as Topic; Diclofenac; Female; Flurbiprofen; Humans; Male; Middle Aged; Phenylacetate | 1983 |
A multicentre study of diclofenac sodium slow-release (Voltaren Retard) in the treatment of rheumatic disorders in the Kingdom of Saudi Arabia.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Delayed-Action Preparations; Diclofenac; Fem | 1984 |
Ionization with diclofenac sodium in rheumatic disorders: a double-blind placebo-controlled trial.
Topics: Adult; Clinical Trials as Topic; Combined Modality Therapy; Diclofenac; Double-Blind Method; Electri | 1984 |
[An open noncomparative multicenter trial of diclofenac in rheumatic diseases].
Topics: Chemical Phenomena; Chemistry; Clinical Trials as Topic; Diclofenac; Humans; Phenylacetates; Rheumat | 1980 |
[Diclofenac (Voltaren) - post-marketing evaluation. An open study on patients with rheumatic diseases].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Diclofenac; Female; Humans; Male; Middle Aged; Ph | 1981 |
[Clinical experiences with the new antirheumatic diclofenac].
Topics: Adult; Aged; Alanine Transaminase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Clinical Tria | 1982 |
[Sodium diclofenac in the ambulatory therapy of joint inflammation and pain. Multicentric open-ended research performed by 223 Italian physicians].
Topics: Adult; Aged; Ambulatory Care; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac | 1982 |
[A trial of the use of the preparation Arthrotec for treating rheumatic diseases].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Fem | 1995 |
A placebo-controlled study of the efficacy and tolerability of a nonsteroidal anti-inflammatory drug, DHEP plaster, in inflammatory peri- and extra-articular rheumatological diseases.
Topics: Administration, Cutaneous; Adult; Aged; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Fema | 1993 |
Efficacy and tolerability of a topical NSAID patch (local action transcutaneous flurbiprofen) and oral diclofenac in the treatment of soft-tissue rheumatism.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, | 1997 |
Prevention of gastroduodenal damage with omeprazole in patients receiving continuous NSAIDs treatment. A double blind placebo controlled study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Double-Blind Method; Endosco | 1998 |
Double-blind controlled clinical study of the efficacy and tolerability of diclofenac-N-(2-hydroxyethyl)-pyrrolidine lecithin gel compared with diclofenac-N-(2-hydroxyethyl)-pyrrolidine gel in patients with peri and extraarticular inflammatory diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Phar | 1999 |
A comparative study of subsyde-CR versus meloxicam in rheumatic disorders.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Meloxicam; Middle Aged; P | 2000 |
[Diclofenac in the treatment of inflammatory and degenerative diseases of the locomotor system].
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Humans; Indomethacin; Inflammati | 1977 |
[Clinical testing of diclofenac sodium in degenerative extra-articular rheumatic diseases].
Topics: Adult; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Humans; Ibuprofen; Middle Aged; Periar | 1977 |
[Experiences with the use of sodium diclofenac (Voltaren) in rheumatic diseases].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Drug Tole | 1978 |
A comparative short-term trial with Voltaren (diclofenac sodium) and naproxen in soft-tissue rheumatism.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Hum | 1978 |
Report on a long-term tolerability study of up to two years with diclofenac sodium (Voltaren).
Topics: Blood Cells; Blood Glucose; Blood Pressure; Blood Sedimentation; Body Weight; Clinical Trials as Top | 1978 |
[Use of vol'taren in rheumatological practice].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Humans; Middle Aged; O | 1978 |
How long should long be? Long-term trials in rheumatic diseases.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Humans; Indomethacin; | 1979 |
[Effectiveness and safety of Lubor capsules in patients with gonarthrosis and extra-articular rheumatism].
Topics: Adult; Aged; Arthritis; Capsules; Diclofenac; Double-Blind Method; Female; Humans; Knee Joint; Male; | 1991 |
[Clinical experiences with tenoxicam. Preliminary results of a multicenter study].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Human | 1991 |
[Multicenter open trial of Voltaren gel in patients with rheumatism and traumatic tissue inflammation].
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Gels; Human | 1990 |
[Clinical profile of acemetacin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Indomethacin; Rand | 1990 |
[Double-blind randomized multicenter study with tenoxicam, piroxicam and diclofenac sodium retard in the treatment of ambulatory patients with arthroses and soft tissue rheumatism].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Doubl | 1989 |
Diclofenac.
Topics: Diclofenac; Double-Blind Method; Humans; Randomized Controlled Trials as Topic; Rheumatic Diseases | 1989 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
Worldwide clinical safety experience with diclofenac.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; France; Humans; Ibuprofen; Japan; Osteoarthritis; Rhe | 1985 |
38 other studies available for diclofenac and Rheumatic Diseases
| Article | Year |
|---|---|
How safe is Celecoxib for Asian-Indian patients with rheumatic diseases?
Topics: Adult; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Drug Substitution; Female; Humans; Hyperten | 2013 |
Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chi-Square Distribution; Cyclo | 2011 |
[Acid coxibs, NO donors, cytokine inhibitors. New beginnings against rheumatism].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Cyclooxygenase Inhibitors; C | 2002 |
[Pain therapy in rheumatism. After 65 years of age coxibs are the best choice].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cyclooxygenase Inhibitors; Dicl | 2003 |
Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; F | 2006 |
[By what means does the rheumatic patient with gastrointestinal risks fare best?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Controlled Clinical Trials as Topic; | 2007 |
[Effect of indocide and voltaren on blood coagulability in surgical interventions on rheumatology patients].
Topics: Adult; Aged; Blood Coagulation; Diclofenac; Humans; Indomethacin; Middle Aged; Phenylacetates; Preop | 1984 |
Diclofenac sodium: blood concentration of the slow-release form and influence on the metabolism of kallikrein.
Topics: Adult; Delayed-Action Preparations; Diclofenac; Female; Humans; Kallikreins; Male; Osteoarthritis; P | 1984 |
[Experiences with the 14C-aminopyrine breath test in liver cirrhosis and under the effect of sodium diclofenac (Voltaren)].
Topics: Adult; Aged; Aminopyrine; Breath Tests; Diclofenac; Female; Humans; Liver; Liver Cirrhosis; Male; Mi | 1983 |
[Interactions of antirheumatic and anti-inflammatory agents].
Topics: Aluminum Hydroxide; Aminopyrine; Anti-Inflammatory Agents; Biotransformation; Diclofenac; Drug Inter | 1983 |
[Effect of antirheumatic preparations on myocardial contractile function].
Topics: Adolescent; Adult; Aspirin; Dexamethasone; Diclofenac; Drug Evaluation; Drug Therapy, Combination; H | 1981 |
[Comparative efficacy of prednisolone and modern nonsteroid anti-inflammatory agents (voltaren and indomethacin) in the therapy of acute rheumatism].
Topics: Acute Disease; Adolescent; Adult; Diclofenac; Hemodynamics; Humans; Indomethacin; Male; Phenylacetat | 1981 |
Patterns of rheumatic diseases and antirheumatic drug usage in 11931 Indian patients.
Topics: Adolescent; Adult; Age Distribution; Diclofenac; Female; Humans; India; Male; Middle Aged; Rheumatic | 1993 |
Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs.
Topics: Adenosine; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chymases; Cyclosporine; Di | 1997 |
[Results of efficacy study with diclofenac/orphenadrine infusions in patients with musculoskeletal diseases and functional disorders].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dos | 1998 |
Economic comparison of nimesulide and diclofenac, and the incidence of adverse events in the treatment of rheumatic disease in Greece.
Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Cyclooxygenase Inhi | 1999 |
[Evaluation of parameters of inflammation in the clinical trial of sodic diclofanac in rheumatology].
Topics: Adult; Aged; Arthritis, Rheumatoid; Diclofenac; Drug Evaluation; Female; Humans; Middle Aged; Osteoa | 1977 |
[Clinical experience with diclophenac in rheumatic diseases].
Topics: Diclofenac; Drug Evaluation; Female; Humans; Male; Middle Aged; Phenylacetates; Rheumatic Diseases | 1977 |
[Personal experiences with Voltaren under ambulatory and hospital therapy of rheumatic patients].
Topics: Adult; Aged; Ambulatory Care; Diclofenac; Drug Evaluation; Female; Hospitalization; Humans; Male; Mi | 1977 |
Quantitative determination of sodium-o-[(2,6-dichlorophenyl)-amino]phenylacetate (diclofenac) in human blood plasma or serum.
Topics: Acylation; Chromatography, Liquid; Diclofenac; Humans; Phenylacetates; Rheumatic Diseases; Time Fact | 1977 |
[The effect of diclofenac sodium on the metabolism of diabetics in qualitative diet therapy with an without tolbuamide. A clinically oriented study in aged diabetics with rheumatic disease].
Topics: Adult; Aged; Diabetes Mellitus; Diclofenac; Drug Interactions; Female; Humans; Male; Middle Aged; Ph | 1978 |
[Clinical trial of a new anti-inflammatory agent: Voltarene].
Topics: Adult; Aged; Anti-Inflammatory Agents; Diclofenac; Drug Evaluation; Female; Humans; Male; Middle Age | 1977 |
[Voltaren in the treatment of rheumatic diseases].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Diclofenac; Female; Humans; Male; Phenylacetates; Rheumati | 1977 |
[Current anti-rheumatism agents].
Topics: Allopurinol; Anti-Inflammatory Agents; Diclofenac; Glucocorticoids; Humans; Indomethacin; Rheumatic | 1978 |
[Effect of anti-inflammatory treatment by diclofenac on blood sedimentation especially during arthroses].
Topics: Adolescent; Adult; Aged; Aging; Blood Sedimentation; Diclofenac; Female; Humans; Joint Diseases; Mal | 1978 |
A long-term investigation of a new antirheumatic drug, diclofenac sodium (Voltaren).
Topics: Adult; Aged; Blood Glucose; Blood Platelets; Blood Sedimentation; Creatinine; Diclofenac; Drug Evalu | 1978 |
[Therapeutic efficacy and tolerance of a new drug, sodium diclofenac, in inflammatory and metabolic rheumatism].
Topics: Adult; Aged; Arthritis, Rheumatoid; Diclofenac; Drug Evaluation; Female; Gout; Humans; Male; Middle | 1978 |
[Panmyelopathy after administration of diclofenac?].
Topics: Adolescent; Adult; Bone Marrow Diseases; Diclofenac; Female; Humans; Male; Phenylacetates; Rheumatic | 1979 |
The influence of diclofenac sodium (Voltarol) on free, protein-bound and total plasma L-tryptophan in adult healthy male subjects.
Topics: Adult; Binding, Competitive; Blood Protein Electrophoresis; Blood Proteins; Diclofenac; Hematologic | 1979 |
[The use of Voltaren for the rehabilitation of rheumatic conditions (author's transl)].
Topics: Anti-Inflammatory Agents; Diclofenac; Drug Evaluation; Drug Tolerance; Female; Humans; Male; Phenyla | 1978 |
[Voltaren in orthopedics].
Topics: Adult; Aged; Diclofenac; Female; Humans; Male; Middle Aged; Phenylacetates; Rheumatic Diseases | 1979 |
Diclofenac sodium (Voltarol): drug interactions and special studies.
Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Coagulation Factors; Blood Glucose; | 1979 |
The economic consequences of NSAID-induced gastropathy: the French context.
Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Duodenal Ulce | 1992 |
Anti-inflammatory efficacy versus gastrointestinal safety: a dilemma resolved? Introduction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Drug Combinations; Gastr | 1992 |
Clinical experiences in the treatment of pain in rheumatology.
Topics: Adult; Aged; Diclofenac; Female; Humans; Indomethacin; Male; Meclofenamic Acid; Middle Aged; Oxyphen | 1991 |
Antirheumatic medication in pregnancy.
Topics: Animals; Diclofenac; Female; Humans; Mice; Pregnancy; Pregnancy Complications; Rabbits; Rats; Rheuma | 1985 |
Symposium on rheumatology and worldwide experience with diclofenac. Jamaica, November 30 to December 2, 1984.
Topics: Animals; Diclofenac; Humans; Rheumatic Diseases | 1985 |
Pharmacokinetic factors as causes of variability in response to non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Bile; Biological Availability; Diclofenac; Humans; Indomethacin; Kinetics; | 1985 |