Page last updated: 2024-10-26

diclofenac and Purpura, Thrombocytopenic, Idiopathic

diclofenac has been researched along with Purpura, Thrombocytopenic, Idiopathic in 3 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.

Research Excerpts

ExcerptRelevanceReference
"Diclofenac has frequently been implicated as the cause of immune hemolytic anemias and less frequently of immune thrombocytopenia."2.42Diclofenac-induced antibodies against RBCs and platelets: two case reports and a concise review. ( Ahrens, N; Aslan, T; Hoffmann, T; Kiesewetter, H; Meyer, O; Salama, A, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Yanagimachi, N1
Obara, N1
Sakata-Yanagimoto, M1
Chiba, S1
Doki, K1
Homma, M1
Meyer, O1
Hoffmann, T1
Aslan, T1
Ahrens, N1
Kiesewetter, H1
Salama, A1
de Quirós, JF1
Pinto, V1
Hevia, S1
Vigón, R1

Reviews

1 review available for diclofenac and Purpura, Thrombocytopenic, Idiopathic

ArticleYear
Diclofenac-induced antibodies against RBCs and platelets: two case reports and a concise review.
    Transfusion, 2003, Volume: 43, Issue:3

    Topics: Adult; Aged; Autoantibodies; Azepines; Blood Platelets; Coombs Test; Diclofenac; Erythrocytes; Femal

2003

Other Studies

2 other studies available for diclofenac and Purpura, Thrombocytopenic, Idiopathic

ArticleYear
A simple HPLC assay for determining eltrombopag concentration in human serum.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:5

    Topics: Benzoates; Chromatography, High Pressure Liquid; Diclofenac; Drug Monitoring; Humans; Hydrazines; Pu

2021
Immune complex-mediated haemolytic anaemia and Evans syndrome induced by diclofenac.
    Vox sanguinis, 1997, Volume: 72, Issue:2

    Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Di

1997