diclofenac has been researched along with Pulmonary Hypertension in 6 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a case of severe pulmonary hypertension and transient right-sided hypertrophic cardiomyopathy in a neonate, caused by premature closure of ductus arteriosus after short-term maternal use of diclofenac sodium (Voltaren)." | 7.72 | Maternal diclofenac sodium ingestion and severe neonatal pulmonary hypertension. ( Lee, WH; Siu, KL, 2004) |
| " This report describes a term newborn with severe persistent pulmonary hypertension due to premature closure of the ductus arteriosus following a 5 day maternal treatment with diclofenac two weeks before delivery." | 7.70 | Severe pulmonary hypertension in a neonate caused by premature closure of the ductus arteriosus following maternal treatment with diclofenac: a case report. ( Klinge, J; Krüger, C; Scharf, J; Singer, H; Zenker, M, 1998) |
| " The effects of cyclo-oxygenase pathway inhibition by diclofenac on the endotoxin shock response and ET-1 turnover, were investigated in five groups of pigs." | 7.69 | Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig. ( Lundberg, JM; Rudehill, A; Weitzberg, E, 1995) |
| "To prevent endotoxin-induced pulmonary hypertension in the pig with a combination of a nonpeptide mixed endothelin receptor antagonist, bosentan, and a cyclooxygenase inhibitor, diclofenac." | 7.69 | The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock. ( Hemsén, A; Lundberg, JM; Rudehill, A; Wanecek, M; Weitzberg, E, 1997) |
| "The acute pressure reaction after air embolism is mainly mediated via ET-1 by an ETA receptor related mechanism." | 5.30 | The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs. ( Heller, A; Koch, T; Neuhof, H; Patt, B; Schmeck, J; van Ackern, K, 1998) |
| "We describe a case of severe pulmonary hypertension and transient right-sided hypertrophic cardiomyopathy in a neonate, caused by premature closure of ductus arteriosus after short-term maternal use of diclofenac sodium (Voltaren)." | 3.72 | Maternal diclofenac sodium ingestion and severe neonatal pulmonary hypertension. ( Lee, WH; Siu, KL, 2004) |
| " This report describes a term newborn with severe persistent pulmonary hypertension due to premature closure of the ductus arteriosus following a 5 day maternal treatment with diclofenac two weeks before delivery." | 3.70 | Severe pulmonary hypertension in a neonate caused by premature closure of the ductus arteriosus following maternal treatment with diclofenac: a case report. ( Klinge, J; Krüger, C; Scharf, J; Singer, H; Zenker, M, 1998) |
| " The effects of cyclo-oxygenase pathway inhibition by diclofenac on the endotoxin shock response and ET-1 turnover, were investigated in five groups of pigs." | 3.69 | Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig. ( Lundberg, JM; Rudehill, A; Weitzberg, E, 1995) |
| "To prevent endotoxin-induced pulmonary hypertension in the pig with a combination of a nonpeptide mixed endothelin receptor antagonist, bosentan, and a cyclooxygenase inhibitor, diclofenac." | 3.69 | The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock. ( Hemsén, A; Lundberg, JM; Rudehill, A; Wanecek, M; Weitzberg, E, 1997) |
| "The acute pressure reaction after air embolism is mainly mediated via ET-1 by an ETA receptor related mechanism." | 1.30 | The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs. ( Heller, A; Koch, T; Neuhof, H; Patt, B; Schmeck, J; van Ackern, K, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siu, KL | 1 |
| Lee, WH | 1 |
| Weitzberg, E | 2 |
| Lundberg, JM | 2 |
| Rudehill, A | 2 |
| Wanecek, M | 1 |
| Hemsén, A | 1 |
| Schmeck, J | 2 |
| Koch, T | 2 |
| Patt, B | 1 |
| Heller, A | 1 |
| Neuhof, H | 1 |
| van Ackern, K | 1 |
| Zenker, M | 1 |
| Klinge, J | 1 |
| Krüger, C | 1 |
| Singer, H | 1 |
| Scharf, J | 1 |
| Konrad, C | 1 |
| Schöffel, S | 1 |
| Wendel-Wellner, M | 1 |
| Gluth, H | 1 |
| Krafft, P | 1 |
6 other studies available for diclofenac and Pulmonary Hypertension
| Article | Year |
|---|---|
Maternal diclofenac sodium ingestion and severe neonatal pulmonary hypertension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiomyopathy, Hypertrophic; Diclofenac; Female; Humans; H | 2004 |
Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Diclofenac; E | 1995 |
The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock.
Topics: Animals; Bosentan; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Endothelin Rece | 1997 |
The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Emboli | 1998 |
Severe pulmonary hypertension in a neonate caused by premature closure of the ductus arteriosus following maternal treatment with diclofenac: a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ductus Arteriosus; Female; Humans; Hypertension | 1998 |
Interaction of acetylcholine and endothelin-1 in the modulation of pulmonary arterial pressure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Cyclooxy | 2000 |