diclofenac has been researched along with Pulmonary Embolism in 5 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute pressure reaction after air embolism is mainly mediated via ET-1 by an ETA receptor related mechanism." | 5.30 | The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs. ( Heller, A; Koch, T; Neuhof, H; Patt, B; Schmeck, J; van Ackern, K, 1998) |
| "Anaphylaxis, acute coronary syndrome and pulmonary embolism are conditions commonly seen in the acute medical setting which can be difficult to diagnose." | 1.34 | Anaphylactic shock: the great mimic. ( Birns, J; Ibrahim, MA; Yong, PF, 2007) |
| "The acute pressure reaction after air embolism is mainly mediated via ET-1 by an ETA receptor related mechanism." | 1.30 | The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs. ( Heller, A; Koch, T; Neuhof, H; Patt, B; Schmeck, J; van Ackern, K, 1998) |
| "Diclofenac inhibits the increase in both pulmonary arterial pressure and EVLW during reperfusion and reventilation of LLL." | 1.29 | Effect of cyclooxygenase inhibition in a canine model of unilateral pulmonary occlusion and reperfusion. ( Albrecht, DM; Krieter, H; Segiet, W; Stieber, C; van Ackern, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jimenez, D | 1 |
| Nieto, R | 1 |
| Corres, J | 1 |
| Fernández-Golfín, C | 1 |
| Barrios, D | 1 |
| Morillo, R | 1 |
| Quezada, CA | 1 |
| Huisman, M | 1 |
| Yusen, RD | 1 |
| Kline, J | 1 |
| Yong, PF | 1 |
| Birns, J | 1 |
| Ibrahim, MA | 1 |
| Segiet, W | 1 |
| Krieter, H | 1 |
| Stieber, C | 1 |
| Albrecht, DM | 1 |
| van Ackern, K | 2 |
| Schmeck, J | 1 |
| Koch, T | 1 |
| Patt, B | 1 |
| Heller, A | 1 |
| Neuhof, H | 1 |
| Michot, F | 1 |
| Ajdacic, K | 1 |
| Glaus, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Diclofenac for Patients With Acute Submassive Pulmonary Embolism: a Randomized Clinical Trial[NCT01590342] | Phase 2/Phase 3 | 34 participants (Actual) | Interventional | 2012-05-31 | Terminated (stopped due to Low recruitment rate) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for diclofenac and Pulmonary Embolism
| Article | Year |
|---|---|
Diclofenac for reversal of right ventricular dysfunction in acute normotensive pulmonary embolism: A pilot study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Pilot Projects; Pul | 2018 |
A double-blind clinical trial to determine if an interaction exists between diclofenac sodium and the oral anticoagulant acenocoumarol (nicoumalone).
Topics: Acenocoumarol; Angina Pectoris; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Interac | 1975 |
3 other studies available for diclofenac and Pulmonary Embolism
| Article | Year |
|---|---|
Anaphylactic shock: the great mimic.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Coronary Disease; Diagnosis, Differenti | 2007 |
Effect of cyclooxygenase inhibition in a canine model of unilateral pulmonary occlusion and reperfusion.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dogs; | 1995 |
The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Emboli | 1998 |