Page last updated: 2024-10-26

diclofenac and Pseudophakia

diclofenac has been researched along with Pseudophakia in 9 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Pseudophakia: Presence of an intraocular lens after cataract extraction.

Research Excerpts

ExcerptRelevanceReference
" Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application."9.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."9.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)
"Although NSAID therapy seems to potentiate the improvements produced by corticosteroids and antivascular endothelial growth factor therapy for chronic pseudophakic cystoid macular edema, only nepafenac- and bromfenac-treated eyes showed reduced retinal thickness at 12 weeks and 16 weeks."5.14NSAIDs in combination therapy for the treatment of chronic pseudophakic cystoid macular edema. ( Bahrani, H; Fox, JE; Warren, KA, 2010)
" Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application."5.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."5.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Cagini, C1
Pellegrino, A1
Cerquaglia, A1
Iaccheri, B1
Lupidi, M1
Fiore, T1
Warren, KA1
Bahrani, H1
Fox, JE1
Romac, I1
Gabrić, N1
Dekaris, I1
Barisić, A1
Gallego-Pinazo, R1
Martínez Castillo, S1
Dolz-Marco, R1
Lleó-Pérez, A1
Díaz-Llopis, M1
Rho, DS1
Neumayer, T1
Buehl, W1
Findl, O1
Miyake, K3
Nishimura, K1
Harino, S1
Ota, I3
Asano, S1
Kondo, N1
Miyake, S3
Maekubo, K2
Ichihashi, S2
Ibaraki, N1
Akura, J1
Shibuya, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Control Study to Investigate if the Continuation of Prostaglandin Analogue Treatments in the Post-operative Phase of Glaucoma Patients Undergoing Cataract Surgery Increases the Incidence of Cystoid Macular Oedema.[NCT03292796]Phase 256 participants (Actual)Interventional2016-12-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for diclofenac and Pseudophakia

ArticleYear
Comparison of the Effect of Diclofenac 0.1% and Nepafenac 0.1% on Aqueous Flare in Patients Undergoing Cataract Surgery: A Prospective Randomized Study.
    Current eye research, 2020, Volume: 45, Issue:9

    Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueou

2020
NSAIDs in combination therapy for the treatment of chronic pseudophakic cystoid macular edema.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodie

2010
Treatment of acute pseudophakic cystoid macular edema: Diclofenac versus ketorolac.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:12

    Topics: Administration, Topical; Aged; Cyclooxygenase Inhibitors; Diclofenac; Drug Evaluation; Female; Human

2003
Effect of topical prednisolone and diclofenac on the short-term change in morphology of posterior capsular opacification.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ca

2006
The effect of topical diclofenac on choroidal blood flow in early postoperative pseudophakias with regard to cystoid macular edema formation.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:12

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Blood-A

2007
Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:1

    Topics: Aged; Blood-Aqueous Barrier; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Fluoresce

1999
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory

2001

Other Studies

2 other studies available for diclofenac and Pseudophakia

ArticleYear
Resolution of pseudophakic cystoid macular edema with combination therapy of topical corticosteroids and nonsteroidal anti-inflammatory drugs.
    Collegium antropologicum, 2011, Volume: 35 Suppl 2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Diclofenac; Drug Therapy, Combination;

2011
[Analysis of prognostic factors by spectral-domain optical coherence tomography in pseudophakic cystoid macular oedema].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:1

    Topics: Acetazolamide; Aged; Anti-Inflammatory Agents; Diclofenac; Female; Humans; Macular Edema; Male; Post

2012