diclofenac has been researched along with Pancreatic Neoplasms in 8 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to investigate the preventive effect of oral diclofenac on pancreatitis after ERCP in a multicenter, randomized, prospective, placebo-controlled, double-blind trial." | 9.22 | No Benefit of Oral Diclofenac on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis. ( Doi, S; Hayashi, T; Hisai, H; Ishiwatari, H; Iwashita, T; Kato, J; Kawakami, H; Kawakubo, K; Matsusaki, S; Ono, M; Sakamoto, N; Sonoda, T; Urata, T; Yasuda, I, 2016) |
| "We aimed to investigate the preventive effect of oral diclofenac on pancreatitis after ERCP in a multicenter, randomized, prospective, placebo-controlled, double-blind trial." | 5.22 | No Benefit of Oral Diclofenac on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis. ( Doi, S; Hayashi, T; Hisai, H; Ishiwatari, H; Iwashita, T; Kato, J; Kawakami, H; Kawakubo, K; Matsusaki, S; Ono, M; Sakamoto, N; Sonoda, T; Urata, T; Yasuda, I, 2016) |
| "We present a first description of a pancreatic cancer patient treated with standard chemotherapy and TL-118, an anti-angiogenic combination of 4 drugs that target non-overlapping aspects of the angiogenic process (Provided by Tiltan Pharma Ltd for compassionate use)." | 1.39 | TL-118-anti-angiogenic treatment in pancreatic cancer: a case report. ( Appelbaum, L; Breuer, S; Hubert, A; Maimon, O; Peretz, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Narożna, M | 1 |
| Krajka-Kuźniak, V | 1 |
| Kleszcz, R | 1 |
| Baer-Dubowska, W | 1 |
| Liu, W | 1 |
| Yu, X | 1 |
| Yuan, Y | 1 |
| Feng, Y | 1 |
| Wu, C | 1 |
| Huang, C | 1 |
| Xie, P | 1 |
| Li, S | 1 |
| Li, X | 1 |
| Wang, Z | 1 |
| Qi, L | 1 |
| Chen, Y | 1 |
| Shi, L | 1 |
| Li, MJ | 1 |
| Huang, Z | 1 |
| Tang, B | 1 |
| Chang, A | 1 |
| Hao, J | 1 |
| Breuer, S | 1 |
| Maimon, O | 1 |
| Appelbaum, L | 1 |
| Peretz, T | 1 |
| Hubert, A | 1 |
| Nicholson, JA | 1 |
| Greenhalf, W | 1 |
| Jackson, R | 1 |
| Cox, TF | 1 |
| Butler, JV | 1 |
| Hanna, T | 1 |
| Harrison, S | 1 |
| Grocock, CJ | 1 |
| Halloran, CM | 1 |
| Howes, NR | 1 |
| Raraty, MG | 1 |
| Ghaneh, P | 1 |
| Johnstone, M | 1 |
| Sarkar, S | 1 |
| Smart, HL | 1 |
| Evans, JC | 1 |
| Aithal, GP | 1 |
| Sutton, R | 1 |
| Neoptolemos, JP | 1 |
| Lombard, MG | 1 |
| Ishiwatari, H | 1 |
| Urata, T | 1 |
| Yasuda, I | 1 |
| Matsusaki, S | 1 |
| Hisai, H | 1 |
| Kawakami, H | 1 |
| Ono, M | 1 |
| Iwashita, T | 1 |
| Doi, S | 1 |
| Kawakubo, K | 1 |
| Hayashi, T | 1 |
| Sonoda, T | 1 |
| Sakamoto, N | 1 |
| Kato, J | 1 |
| Mayorek, N | 1 |
| Naftali-Shani, N | 1 |
| Grunewald, M | 1 |
| Okuyama, M | 1 |
| Shibata, T | 1 |
| Morita, T | 1 |
| Kitada, M | 1 |
| Tukahara, Y | 1 |
| Fukushima, Y | 1 |
| Ikeda, K | 1 |
| Fuzita, J | 1 |
| Shimano, T | 1 |
| Polati, E | 1 |
| Finco, G | 1 |
| Gottin, L | 1 |
| Bassi, C | 1 |
| Pederzoli, P | 1 |
| Ischia, S | 1 |
3 trials available for diclofenac and Pancreatic Neoplasms
| Article | Year |
|---|---|
No Benefit of Oral Diclofenac on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amylases; Anti-Inflammatory Agents, Non-Steroidal; Au | 2016 |
A comparison of intraoperative celiac plexus block with pharmacological therapy as a treatment for pain of unresectable pancreatic cancer.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerv | 2002 |
Prospective randomized double-blind trial of neurolytic coeliac plexus block in patients with pancreatic cancer.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Celiac Plexus; Diclofen | 1998 |
5 other studies available for diclofenac and Pancreatic Neoplasms
| Article | Year |
|---|---|
Indomethacin and Diclofenac Hybrids with Oleanolic Acid Oximes Modulate Key Signaling Pathways in Pancreatic Cancer Cells.
Topics: Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Cyclooxygenase Inhibitors; Diclofenac; | 2022 |
CD73, a Promising Therapeutic Target of Diclofenac, Promotes Metastasis of Pancreatic Cancer through a Nucleotidase Independent Mechanism.
Topics: Carcinoma, Pancreatic Ductal; Diclofenac; Gemcitabine; Humans; Nucleotidases; Pancreatic Neoplasms | 2023 |
CD73, a Promising Therapeutic Target of Diclofenac, Promotes Metastasis of Pancreatic Cancer through a Nucleotidase Independent Mechanism.
Topics: Carcinoma, Pancreatic Ductal; Diclofenac; Gemcitabine; Humans; Nucleotidases; Pancreatic Neoplasms | 2023 |
CD73, a Promising Therapeutic Target of Diclofenac, Promotes Metastasis of Pancreatic Cancer through a Nucleotidase Independent Mechanism.
Topics: Carcinoma, Pancreatic Ductal; Diclofenac; Gemcitabine; Humans; Nucleotidases; Pancreatic Neoplasms | 2023 |
CD73, a Promising Therapeutic Target of Diclofenac, Promotes Metastasis of Pancreatic Cancer through a Nucleotidase Independent Mechanism.
Topics: Carcinoma, Pancreatic Ductal; Diclofenac; Gemcitabine; Humans; Nucleotidases; Pancreatic Neoplasms | 2023 |
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cyclophos | 2013 |
Incidence of post-ERCP pancreatitis from direct pancreatic juice collection in hereditary pancreatitis and familial pancreatic cancer before and after the introduction of prophylactic pancreatic stents and rectal diclofenac.
Topics: Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Tumor; Cholangio | 2015 |
Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Arginase; Cell Proliferation; Di | 2010 |