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diclofenac and Nephrotic Syndrome

diclofenac has been researched along with Nephrotic Syndrome in 13 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated."7.70[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999)
"Nephrotic syndrome, with or without concomitant tubulointerstitial nephritis, is a rare renal adverse effect of NSAIDs."5.37Safe administration of celecoxib to a patient with repeated episodes of nephrotic syndrome induced by NSAIDs. ( Knotek, M; Ljubanovic, D; Mihovilovic, K, 2011)
"A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated."3.70[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999)
" Indomethacin, diclofenac-sodium and flurbiprofen decreased proteinuria, glomerular filtration rate, plasma renin activity and renal prostaglandin E2 excretion by 59%, 19%, 55% and 68% respectively."3.67Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs. ( de Jong, PE; de Zeeuw, D; Donker, AJ; Pratt, JJ; van der Hem, GK; Vriesendorp, R, 1986)
"Nephrotic syndrome, with or without concomitant tubulointerstitial nephritis, is a rare renal adverse effect of NSAIDs."1.37Safe administration of celecoxib to a patient with repeated episodes of nephrotic syndrome induced by NSAIDs. ( Knotek, M; Ljubanovic, D; Mihovilovic, K, 2011)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's7 (53.85)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mihovilovic, K1
Ljubanovic, D1
Knotek, M1
Vereerstraeten, P1
Thoua, Y1
Goldman, M1
Schandene, L1
Vanherweghem, JL1
Toussaint, C1
Cucurull, E1
Borrellas, X1
Fort, J1
Camps, J1
Piera, L1
Lecoules, S1
Duvic, C1
Hérody, M1
Nédélec, G1
Révai, T1
Harmos, G1
Poux, JM1
Tifoura, A1
Smaoui, S1
Pernin, F1
Daniel, L1
Mohammed, EP1
Stevens, JM1
Rubio García, JA1
Téllez Molina, MJ1
Tattersall, J1
Greenwood, R1
Farrington, K1
Guth, C1
Weisshuhn, I1
Göbel, U1
Laske, HR1
Müller, V1
Natusch, R1
Dimitrakov, D1
Pavlova, M1
Natov, S1
Simeonov, S1
Arimura, Y1
Nakabayashi, K1
Gotoh, K1
Kamiya, Y1
Inoue, A1
Kitamoto, K1
Nagasawa, T1
Vriesendorp, R1
de Zeeuw, D1
de Jong, PE1
Donker, AJ1
Pratt, JJ1
van der Hem, GK1

Reviews

1 review available for diclofenac and Nephrotic Syndrome

ArticleYear
[Nephrotic syndrome and oligo-anuria complicating treatment with diclofenac].
    Annales de medecine interne, 2000, Volume: 151, Issue:1

    Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclof

2000

Other Studies

12 other studies available for diclofenac and Nephrotic Syndrome

ArticleYear
Safe administration of celecoxib to a patient with repeated episodes of nephrotic syndrome induced by NSAIDs.
    Clinical drug investigation, 2011, Volume: 31, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans;

2011
[Reversible nephrotic syndrome and acute renal failure associated with alclofenac administration].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1982, Jul-27, Volume: 71, Issue:30

    Topics: Acute Kidney Injury; Diclofenac; Eosinophilia; Humans; Kidney; Male; Middle Aged; Nephrotic Syndrome

1982
[Nephrotoxicity caused by diclofenac].
    Revista clinica espanola, 1994, Volume: 194, Issue:1

    Topics: Acute Disease; Aged; Diclofenac; Humans; Male; Nephritis, Interstitial; Nephrotic Syndrome

1994
[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions].
    Presse medicale (Paris, France : 1983), 1999, Feb-13, Volume: 28, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Diclofenac; Dose-R

1999
Nephrotic syndrome and acute interstitial nephritis associated with the use of diclofenac.
    Wiener klinische Wochenschrift, 1999, Jul-09, Volume: 111, Issue:13

    Topics: Acute Disease; Aged; Diclofenac; Female; Humans; Nephritis, Interstitial; Nephrotic Syndrome

1999
Recurrence of Arthrotec-associated nephrotic syndrome with re-challenge.
    Clinical nephrology, 2000, Volume: 53, Issue:6

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Humans;

2000
[Acute renal failure and nephrotic syndrome associated with treatment with diclofenac].
    Revista clinica espanola, 1992, Volume: 191, Issue:5

    Topics: Acute Kidney Injury; Aged; Diclofenac; Humans; Male; Nephrotic Syndrome

1992
Membranous nephropathy associated with diclofenac.
    Postgraduate medical journal, 1992, Volume: 68, Issue:799

    Topics: Diclofenac; Female; Glomerulonephritis, Membranous; Humans; Middle Aged; Nephrotic Syndrome

1992
[Clinical experiences in the use of diclofenac (Rewodina) in the symptomatic treatment of nephrotic syndrome].
    Zeitschrift fur arztliche Fortbildung, 1991, Nov-25, Volume: 85, Issue:22

    Topics: Adult; Blood Pressure; Creatinine; Diclofenac; Electrolytes; Female; Humans; Male; Nephrotic Syndrom

1991
[The nephrotic syndrome as a consequence of Feloran treatment in a female patient with rheumatoid arthritis].
    Vutreshni bolesti, 1990, Volume: 29, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Chronic Disease; Diclofenac; Female; Humans; Nephrosis, Lipoid; Nephrot

1990
[Two cases of acute renal failure and nephrotic syndrome induced by nonsteroidal anti-inflammatory drugs].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1988, Volume: 77, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female;

1988
Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs.
    Clinical nephrology, 1986, Volume: 25, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Flurbiprofen; Glomerular Filtration Rate;

1986