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diclofenac and Myopia

diclofenac has been researched along with Myopia in 23 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of a topical nonsteroidal anti-inflammatory agent, diclofenac, and prednisolone acetate on wound healing, postoperative inflammation, and other clinical parameters in laser in situ keratomileusis (LASIK) patients."5.09Effects of topical diclofenac and prednisolone eyedrops in laser in situ keratomileusis patients. ( Juárez, CP; Luna, JD; Muiño, JC; Vantesone, DL, 1999)
"In eyes with low to moderate myopia, the steroid and diclofenac subgroups had significantly different refractions 2 and 4 months postoperatively but no difference at 6 months; subjective haze grading was consistently lower in the steroid subgroup than in the NSAID subgroups (flurbiprofen, diclofenac) after 2 months."5.08Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy. ( Baek, SH; Chang, JH; Choi, SY; Lee, JH; Wee, WR, 1997)
"To evaluate the ability of topical diclofenac to decrease corneal opacity after excimer laser photorefractive keratectomy (PRK)."3.69Effect of diclofenac on corneal haze after photorefractive keratectomy in rabbits. ( al Reaves, T; McDonnell, PJ; Nassaralla, BA; Szerenyi, K; Wang, XW, 1995)
"The patients were asked to score the postoperative pain in each eye with a visual analog scale at 6, 18, 24, 36, 48, 72, and 96 hours."2.79Comparison of analgesic effect of preoperative topical diclofenac and ketorolac on postoperative pain after photorefractive keratectomy. ( Hong, JP; Im, CY; Kim, EK; Kim, TI; Nam, SM; Seo, KY; Yoon, S, 2014)
"Subjective postoperative pain, symptoms, re-epithelialization rate, and systemic medications were monitored for 2 days following photoablation."2.69A prospective randomized trial of topical soluble 0.1% indomethacin versus 0.1% diclofenac versus placebo for the control of pain following excimer laser photorefractive keratectomy. ( Arne, JL; Assouline, M; David, T; Lasmolles, C; Malecaze, F; Pouliquen, YJ; Renard, G, 1998)
"Diclofenac-treated patients experienced significantly less photophobia, burning/stinging, and ocular pain and took significantly fewer oral narcotic analgesics over the first 24 hours postoperatively than placebo-treated patients."2.68Efficacy and safety of topical diclofenac in reducing ocular pain after excimer photorefractive keratectomy. ( Cherry, PM; Fsadni, MG; Raj, PS; Tutton, MK, 1996)
"Diclofenac sodium was significantly (p < 0."2.68Evaluation of diclofenac sodium 0.1% ophthalmic solution in the treatment of ocular symptoms after bilateral radial keratotomy. ( Gill, DJ; Hettinger, ME; Koester, J; Levy, RH; Robin, JB, 1997)
" Dosing and duration varied, but in all 3 cases diclofenac was used at least 4 times a day for at least 3 days after LASIK."1.32Histopathology of corneal melting associated with diclofenac use after refractive surgery. ( Hsu, JK; Johnston, WT; McDonnell, PJ; Pangalinan, R; Rao, N; Read, RW; Smith, RE, 2003)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (47.83)18.2507
2000's4 (17.39)29.6817
2010's7 (30.43)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Wang, Y1
Shen, F1
Sun, W1
Wang, Q1
Zhao, X1
Mohammadpour, M2
Heidari, Z1
Molani, R1
Marí Cotino, JF1
Suriano, MM1
De La Cruz Aguiló, RI1
Vila-Arteaga, J1
Eslampour, A1
Malaekeh-Nikouei, B1
Abrishami, M2
Bayani, R1
Eslampoor, A1
Ehsaei, A1
Hong, JP1
Nam, SM1
Im, CY1
Yoon, S1
Kim, TI1
Kim, EK1
Seo, KY1
Parker, J1
Tandon, A1
Shtein, RM1
Soong, HK1
Cooney, TN1
Musch, DC1
Mian, SI1
Jabbarvand, M1
Nikdel, M1
Adelpour, M1
Karimi, N1
Hsu, JK1
Johnston, WT1
Read, RW1
McDonnell, PJ2
Pangalinan, R1
Rao, N1
Smith, RE1
Nassaralla, BA1
Szerenyi, K1
Wang, XW1
al Reaves, T1
Eiferman, RA1
Hoffman, RS1
Sher, NA1
Carones, F1
Brancato, R1
Morico, A1
Venturi, E1
Gobbi, PG1
Tutton, MK1
Cherry, PM1
Raj, PS1
Fsadni, MG1
Hettinger, ME1
Gill, DJ1
Robin, JB1
Levy, RH1
Koester, J1
Baek, SH1
Choi, SY1
Chang, JH1
Wee, WR1
Lee, JH1
Assouline, M1
Renard, G1
Arne, JL1
David, T1
Lasmolles, C1
Malecaze, F1
Pouliquen, YJ1
Lee, JS1
Oum, BS1
Lee, BJ1
Lee, SH1
Tomas-Barberan, S1
Fagerholm, P1
Vantesone, DL1
Luna, JD1
Muiño, JC1
Juárez, CP1
McDonald, MB1
Brint, SF1
Caplan, DI1
Bourque, LB1
Shoaf, K1
Shah, S1
Sebai Sarhan, AR1
Doyle, SJ1
Pillai, CT1
Dua, HS1
Ahmed, II1
Breslin, CW1
Mackool, RJ1

Trials

18 trials available for diclofenac and Myopia

ArticleYear
Bandage contact lens soaked in 0.1% diclofenac to relieve early postoperative pain and foreign body sensation after transepithelial photorefractive keratectomy.
    European journal of ophthalmology, 2022, Volume: 32, Issue:6

    Topics: Bandages; Diclofenac; Foreign Bodies; Humans; Lasers, Excimer; Myopia; Pain, Postoperative; Photoref

2022
Comparison Between Diclofenac and Ketorolac Ophthalmic Drops for Pain Management After Photorefractive Keratectomy: A Randomized Clinical Study.
    Eye & contact lens, 2019, Volume: 45, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Humans; Ket

2019
Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:7

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism

2013
Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized, controlled trial.
    Clinical & experimental ophthalmology, 2014, Volume: 42, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dou

2014
Comparison of analgesic effect of preoperative topical diclofenac and ketorolac on postoperative pain after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:10

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Stroma; Diclofenac;

2014
Management of pain with diclofenac after femtosecond-assisted laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:3

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Me

2011
Effect of preemptive topical diclofenac on postoperative pain relief after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:4

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Me

2011
Topical diclofenac reduces pain following photorefractive keratectomy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:8

    Topics: Cornea; Diclofenac; Humans; Laser Therapy; Myopia; Ophthalmic Solutions; Pain Measurement; Pain, Pos

1993
Evaluation of three different approaches to perform excimer laser photorefractive keratectomy for myopia.
    Ophthalmic surgery and lasers, 1996, Volume: 27, Issue:5 Suppl

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; Cyclopentolate; Diclofenac;

1996
Efficacy and safety of topical diclofenac in reducing ocular pain after excimer photorefractive keratectomy.
    Journal of cataract and refractive surgery, 1996, Volume: 22, Issue:5

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Me

1996
Evaluation of diclofenac sodium 0.1% ophthalmic solution in the treatment of ocular symptoms after bilateral radial keratotomy.
    Cornea, 1997, Volume: 16, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Evaluation; Fe

1997
Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; D

1997
A prospective randomized trial of topical soluble 0.1% indomethacin versus 0.1% diclofenac versus placebo for the control of pain following excimer laser photorefractive keratectomy.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Diclofe

1998
Influence of topical treatment on epithelial wound healing and pain in the early postoperative period following photorefractive keratectomy.
    Acta ophthalmologica Scandinavica, 1999, Volume: 77, Issue:2

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C

1999
Effects of topical diclofenac and prednisolone eyedrops in laser in situ keratomileusis patients.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:6

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C

1999
Comparison of ketorolac tromethamine, diclofenac sodium, and moist drops for ocular pain after radial keratotomy.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Humans; Ker

1999
The epithelial flap for photorefractive keratectomy.
    The British journal of ophthalmology, 2001, Volume: 85, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; A

2001
Role of the bandage soft contact lens in the postoperative laser in situ keratomileusis patient.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:12

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Contact Lens

2001

Other Studies

5 other studies available for diclofenac and Myopia

ArticleYear
Central toxic keratopathy: a clinical case series.
    The British journal of ophthalmology, 2013, Volume: 97, Issue:6

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Ciprofloxacin; C

2013
Histopathology of corneal melting associated with diclofenac use after refractive surgery.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Female; Humans

2003
Effect of diclofenac on corneal haze after photorefractive keratectomy in rabbits.
    Ophthalmology, 1995, Volume: 102, Issue:3

    Topics: Administration, Topical; Animals; Cornea; Corneal Opacity; Diclofenac; Drug Therapy, Combination; Fl

1995
Photorefractive keratectomy for astigmatism greater than -2.00 diopters in eyes with low, high, or extreme myopia.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Diclofenac; Female; Follow-Up S

1998
Bandage contact lens after LASIK.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:6

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Contact Lens

2002