diclofenac has been researched along with Musculoskeletal Pain in 10 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adverse events were defined as irritation, gastrointestinal upset/bleed, rectal bleed, and hematemesis." | 5.56 | Determination of efficacy and toxicity of diclofenac microemulsion formulation for musculoskeletal pain: an observational study. ( Banh, HL; Cave, A, 2020) |
| "In acute musculoskeletal pain (strains and sprains) with assessment at about seven days, therapies were diclofenac Emulgel (78% Emulgel, 20% placebo; 2 studies, 314 participants, NNT 1." | 4.95 | Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews. ( Aldington, D; Bell, RF; Derry, S; Gaskell, H; Kalso, EA; Moore, RA; Phillips, T; Wiffen, PJ, 2017) |
| "Topical diclofenac and topical ketoprofen can provide good levels of pain relief beyond carrier in osteoarthritis for a minority of people, but there is no evidence for other chronic painful conditions." | 4.93 | Topical NSAIDs for chronic musculoskeletal pain in adults. ( Conaghan, P; Da Silva, JA; Derry, S; Moore, RA; Wiffen, PJ, 2016) |
| " In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain." | 4.89 | Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013) |
| "Topical NSAIDs can provide good levels of pain relief; topical diclofenac solution is equivalent to that of oral NSAIDs in knee and hand osteoarthritis, but there is no evidence for other chronic painful conditions." | 4.88 | Topical NSAIDs for chronic musculoskeletal pain in adults. ( Derry, S; Moore, RA; Rabbie, R, 2012) |
| "While acute musculoskeletal pain is a frequent complaint, its management is often neglected." | 1.43 | A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain. ( Berben, SA; Doggen, CJ; Gaakeer, MI; IJzerman, MJ; Pierik, JG; van Eenennaam, FL; van Vugt, AB, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banh, HL | 1 |
| Cave, A | 1 |
| Kudsi, SQ | 1 |
| Antoniazzi, CTD | 1 |
| Camponogara, C | 1 |
| Brum, EDS | 1 |
| Brusco, I | 1 |
| Peres, DS | 1 |
| Fischer, SPM | 1 |
| Dalenogare, DP | 1 |
| Stein, CDS | 1 |
| Zaccaron, RP | 1 |
| Silveira, PCL | 1 |
| Moresco, RN | 1 |
| Oliveira, SM | 1 |
| Trevisan, G | 1 |
| van Herwaarden, N | 1 |
| van den Elsen, GAH | 1 |
| de Jong, ICA | 1 |
| Kramers, CK | 1 |
| Kloppenburg, M | 1 |
| van den Bemt, BJF | 1 |
| Derry, S | 3 |
| Wiffen, PJ | 2 |
| Kalso, EA | 1 |
| Bell, RF | 1 |
| Aldington, D | 1 |
| Phillips, T | 1 |
| Gaskell, H | 1 |
| Moore, RA | 3 |
| Ohmichi, Y | 1 |
| Ohmichi, M | 1 |
| Murai, N | 1 |
| Yasui, M | 1 |
| Takeshita, N | 1 |
| Oshibuchi, H | 1 |
| Naito, M | 1 |
| Nakano, T | 1 |
| Sato, J | 1 |
| Stanos, SP | 1 |
| Galluzzi, KE | 1 |
| Pierik, JG | 1 |
| Berben, SA | 1 |
| IJzerman, MJ | 1 |
| Gaakeer, MI | 1 |
| van Eenennaam, FL | 1 |
| van Vugt, AB | 1 |
| Doggen, CJ | 1 |
| Conaghan, P | 1 |
| Da Silva, JA | 1 |
| Jordan, J | 1 |
| Rabbie, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for diclofenac and Musculoskeletal Pain
| Article | Year |
|---|---|
Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews.
Topics: Acute Pain; Adult; Analgesics; Arthritis, Rheumatoid; Capsaicin; Chronic Pain; Diclofenac; Humans; K | 2017 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C | 2013 |
Topical NSAIDs for chronic musculoskeletal pain in adults.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; H | 2016 |
Topical NSAIDs for Acute Musculoskeletal Pain in Adults.
Topics: Acute Pain; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ib | 2016 |
Topical NSAIDs for chronic musculoskeletal pain in adults.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; H | 2012 |
5 other studies available for diclofenac and Musculoskeletal Pain
| Article | Year |
|---|---|
Determination of efficacy and toxicity of diclofenac microemulsion formulation for musculoskeletal pain: an observational study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofena | 2020 |
Characterisation of nociception and inflammation observed in a traumatic muscle injury model in rats.
Topics: Administration, Topical; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Ani | 2020 |
[Topical NSAIDs: ineffective or undervalued?]
Topics: Acute Pain; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Mu | 2021 |
Therapeutic effects of diclofenac, pregabalin, and duloxetine on disuse-induced chronic musculoskeletal pain in rats.
Topics: Animals; Chronic Pain; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Muscle, | 2018 |
A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain.
Topics: Acetaminophen; Adult; Analgesics; Diclofenac; Emergency Service, Hospital; Female; Fentanyl; Follow- | 2016 |