diclofenac has been researched along with Muscle Contraction in 25 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The blueberry extract produced a significant decrease in constrictions induced by acetic acid and caused graded inhibition of the second phase of formalin-induced pain." | 3.76 | Preliminary studies on the antinociceptive activity of Vaccinium ashei berry in experimental animal models. ( Barros, DM; de Castro, MR; de Souza, MM; Dickel, OE; Guterres, L; Henriques, AT; Ramirez, MR, 2010) |
| "The present study shows that meloxicam dose-dependently exhibited systemic antinociceptive action when assessed against neurogenic and inflammatory pain caused by acetic acid, formalin and capsaicin models." | 3.70 | Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice. ( De Freitas, GA; Santos, AR; Vedana, EM, 1998) |
| "Valdecoxib was more potent in proximal specimens of human ureter (EC50=7." | 1.35 | Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo. ( Chaignat, V; Danuser, H; Mevissen, M; Stoffel, MH; Studer, UE; Z'brun, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 12 (48.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smid, SD | 1 |
| Svensson, KM | 1 |
| Ramirez, MR | 1 |
| Guterres, L | 1 |
| Dickel, OE | 1 |
| de Castro, MR | 1 |
| Henriques, AT | 1 |
| de Souza, MM | 1 |
| Barros, DM | 1 |
| Kulkarni, SK | 1 |
| Patil, CS | 1 |
| Jain, NK | 1 |
| Singh, A | 1 |
| Vignaud, A | 1 |
| Cebrian, J | 1 |
| Martelly, I | 1 |
| Caruelle, JP | 1 |
| Ferry, A | 1 |
| Ishihata, A | 1 |
| Sakai, M | 1 |
| Katano, Y | 1 |
| Strapkova, A | 1 |
| Antosova, M | 1 |
| Nosalova, G | 1 |
| Davenport, K | 1 |
| Timoney, AG | 1 |
| Keeley, FX | 1 |
| Shimamura, K | 1 |
| Toba, M | 1 |
| Kimura, S | 1 |
| Ohashi, A | 1 |
| Kitamura, K | 1 |
| Chaignat, V | 1 |
| Danuser, H | 1 |
| Stoffel, MH | 1 |
| Z'brun, S | 1 |
| Studer, UE | 1 |
| Mevissen, M | 1 |
| Pérez Vallina, JR | 2 |
| Cantabrana, B | 2 |
| Hidalgo, A | 2 |
| Menendez Antolin, L | 1 |
| Sanchez, M | 1 |
| Gustafsson, BI | 1 |
| Delbro, DS | 1 |
| Baersch, G | 1 |
| Frölich, JC | 1 |
| Kähönen, M | 3 |
| Tolvanen, JP | 2 |
| Sallinen, K | 1 |
| Wu, X | 3 |
| Pörsti, I | 3 |
| Santos, AR | 1 |
| Vedana, EM | 1 |
| De Freitas, GA | 1 |
| Kalliovalkama, J | 1 |
| Karjala, K | 1 |
| Mäkynen, H | 1 |
| Hutri-Kähönen, N | 1 |
| Jolma, P | 1 |
| Sand, J | 1 |
| Nordback, I | 1 |
| Ylitalo, P | 1 |
| Arvola, P | 1 |
| Marceau, F | 1 |
| Larrivée, JF | 1 |
| Bouthillier, J | 1 |
| Bachvarova, M | 1 |
| Houle, S | 1 |
| Bachvarov, DR | 1 |
| Mastrangelo, D | 1 |
| Wisard, M | 1 |
| Rohner, S | 1 |
| Leisinger, H | 1 |
| Iselin, CE | 1 |
| Lapointe, BM | 2 |
| Frémont, P | 1 |
| Côté, CH | 2 |
| Frenette, J | 1 |
| Downing, SJ | 1 |
| Tay, JI | 1 |
| Maguiness, SD | 1 |
| Watson, A | 1 |
| Leese, HJ | 1 |
| Cole, RS | 1 |
| Fry, CH | 1 |
| Shuttleworth, KE | 1 |
| Thulesius, O | 1 |
| Angelo-Khattar, M | 1 |
| Ali, M | 1 |
| Lundstam, S | 1 |
| Jonsson, O | 1 |
| Kihl, B | 1 |
| Pettersson, S | 1 |
25 other studies available for diclofenac and Muscle Contraction
| Article | Year |
|---|---|
Inhibition of cyclooxygenase-2 and EP1 receptor antagonism reduces human colonic longitudinal muscle contractility in vitro.
Topics: Acetylcholine; Amides; Bimatoprost; Cloprostenol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dic | 2009 |
Preliminary studies on the antinociceptive activity of Vaccinium ashei berry in experimental animal models.
Topics: Acetic Acid; Analgesics; Animals; Anthocyanins; Blueberry Plants; Diclofenac; Disease Models, Animal | 2010 |
Modulatory effect of diclofenac on antispasmodic effect of pitofenone in cholinergic spasm.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Cholinergic Agents; | 2004 |
Effect of anti-inflammatory and antioxidant drugs on the long-term repair of severely injured mouse skeletal muscle.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Curcumin; Cyclooxygenase Inhibit | 2005 |
Vascular contractile effect of urotensin II in young and aged rats: influence of aging and contribution of endothelial nitric oxide.
Topics: Aging; Animals; Aorta, Thoracic; Diclofenac; Endothelium, Vascular; Male; Muscle Contraction; Nitric | 2006 |
Interaction between nitric oxide and prostanoids in the respiratory system.
Topics: Animals; Bronchial Hyperreactivity; Cyclooxygenase Inhibitors; Diclofenac; Guinea Pigs; In Vitro Tec | 2006 |
A comparative in vitro study to determine the beneficial effect of calcium-channel and alpha(1)-adrenoceptor antagonism on human ureteric activity.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents, Non | 2006 |
Clonidine induced endothelium-dependent tonic contraction in circular muscle of the rat hepatic portal vein.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Diclofenac; Endothelium, Vascular; Humans; Hypertensi | 2006 |
Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo.
Topics: Aged; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib | 2008 |
Calcium-and G-protein-related spasmolytic effects of nonsteroidal anti-inflammatory drugs on rat uterus contractions in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Involvement of sodium/calcium exchange in the diclofenac-induced spasmolytic effect on rat uterus.
Topics: Amiloride; Animals; Calcium; Chlorides; Diclofenac; Dose-Response Relationship, Drug; Female; Ion Ex | 1995 |
Motor effects of indomethacin, morphine or vagal nerve stimulation on the feline small intestine in vivo.
Topics: Animals; Aspirin; Autonomic Nervous System; Cats; Diclofenac; Electric Stimulation; Female; Gastroin | 1993 |
A new bioassay to study contractile and relaxant effects of PGE2 on perfused guinea pig trachea.
Topics: Analysis of Variance; Animals; Biological Assay; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone | 1996 |
Influence of gender on control of arterial tone in experimental hypertension.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Apamin; Blood Pressure; Cal | 1998 |
Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice.
Topics: Abdominal Muscles; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Cyclooxygenase I | 1998 |
Losartan and enalapril therapies enhance vasodilatation in the mesenteric artery of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diclofenac; Enalapril; Endothelium; E | 1999 |
Control of mesenteric arterial tone in vitro in humans and rats.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Cromakalim; Diclofenac; Endot | 1999 |
Effect of endogenous kinins, prostanoids, and NO on kinin B1 and B2 receptor expression in the rabbit.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykin | 1999 |
Diclofenac and NS-398, a selective cyclooxygenase-2 inhibitor, decrease agonist-induced contractions of the pig isolated ureter.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Free | 2000 |
Adaptation to lengthening contractions is independent of voluntary muscle recruitment but relies on inflammation.
Topics: Adaptation, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Mac | 2002 |
Lengthening contraction-induced inflammation is linked to secondary damage but devoid of neutrophil invasion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Collagenases; Diclofenac; Dinoprostone | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relatio | 2002 |
The action of the prostaglandins on isolated human ureteric smooth muscle.
Topics: Diclofenac; Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; | 1988 |
The effect of prostaglandin synthesis inhibition on motility of the sheep ureter.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diclofenac; Dinoprost; Humans; Indomethacin; Muscle Contracti | 1987 |
Prostaglandin synthetase inhibition of renal pelvic smooth muscle in the rabbit.
Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, | 1985 |