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diclofenac and Miosis

diclofenac has been researched along with Miosis in 13 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Miosis: Pupillary constriction. This may result from congenital absence of the dilatator pupillary muscle, defective sympathetic innervation, or irritation of the CONJUNCTIVA or CORNEA.

Research Excerpts

ExcerptRelevanceReference
"A prospective, randomized clinical trial was conducted to assess the usefulness of preoperative diclofenac eye drops in maintaining mydriasis during vitrectomy and in reducing postoperative inflammation."9.13Topical administration of diclofenac (1%) in the prevention of miosis during vitrectomy. ( Djalilian, A; Mirshahi, A; Namavari, A; Rafiee, F, 2008)
"Topical ketorolac was a more effective inhibitor of miosis than topical diclofenac during extracapsular cataract extraction and IOL implantation."9.10Topical ketorolac tromethamine 0.5% versus diclofenac sodium 0.1% to inhibit miosis during cataract surgery. ( Srinivasan, R, 2002)
"To compare the efficacy of two topical nonsteroidal anti-inflammatory drugs, diclofenac sodium and flurbiprofen, commonly used prior to cataract surgery to inhibit surgically induced miosis."9.08Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis. ( Roberts, CW, 1996)
"1% (Voltaren) prevents surgically induced miosis during extracapsular cataract extraction in a more long lasting way than indomethacin 1% (Indocid)."9.07[Prevention of peroperative miosis: comparison between prostaglandin inhibitors. Sodium diclofenac and indomethacin in local application]. ( Dimitrakos, SA; Panidou-Kyriakidou, I; Topouzidis, C, 1992)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."7.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)
"Both diclofenac and pranoprofen treatment inhibit surgical-induced miosis."5.19Effect of topical nonsteroidal anti-inflammatory drugs and nuclear hardness on maintenance of mydriasis during phacoemulsification surgery. ( Liu, C; Liu, L; Liu, Y; Wu, M; Ye, S; Zhang, W, 2014)
"A prospective, randomized clinical trial was conducted to assess the usefulness of preoperative diclofenac eye drops in maintaining mydriasis during vitrectomy and in reducing postoperative inflammation."5.13Topical administration of diclofenac (1%) in the prevention of miosis during vitrectomy. ( Djalilian, A; Mirshahi, A; Namavari, A; Rafiee, F, 2008)
"Topical ketorolac was a more effective inhibitor of miosis than topical diclofenac during extracapsular cataract extraction and IOL implantation."5.10Topical ketorolac tromethamine 0.5% versus diclofenac sodium 0.1% to inhibit miosis during cataract surgery. ( Srinivasan, R, 2002)
"1% diclofenac sodium (DS) eyedrops made in China on preventing surgically induced miosis and inflammation."5.09Clinical study of diclofenac sodium eyedrops used before and after cataract operation. ( Wei, H; Zhang, M, 1999)
" Other factors evaluated were the effect of preoperative flurbiprofen (Ocufen) in preventing intraoperative miosis and on postoperative discomfort and the effect of incision size and intraocular carbachol (Miostat) on postoperative comfort."5.08Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery. ( Fry, LL, 1995)
"To compare the efficacy of two topical nonsteroidal anti-inflammatory drugs, diclofenac sodium and flurbiprofen, commonly used prior to cataract surgery to inhibit surgically induced miosis."5.08Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis. ( Roberts, CW, 1996)
" In this study we compared the efficacy of two topical nonsteroidal anti-inflammatory drugs: diclofenac sodium (Naclof) and indomethacin used before cataract surgery to inhibit surgically induced miosis."5.08[The effect of diclofenac sodium and indomethacin used locally for maintenance of pupillary dilatation during cataract surgery]. ( Florek, G; Guzińska, M; Kałuzny, J, 1998)
"1% (Voltaren) prevents surgically induced miosis during extracapsular cataract extraction in a more long lasting way than indomethacin 1% (Indocid)."5.07[Prevention of peroperative miosis: comparison between prostaglandin inhibitors. Sodium diclofenac and indomethacin in local application]. ( Dimitrakos, SA; Panidou-Kyriakidou, I; Topouzidis, C, 1992)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."3.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (61.54)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, C1
Liu, Y1
Ye, S1
Liu, L1
Zhang, W1
Wu, M1
Schultz, T1
Joachim, SC1
Szuler, M1
Stellbogen, M1
Dick, HB1
Mirshahi, A1
Djalilian, A1
Rafiee, F1
Namavari, A1
Zhang, M1
Wei, H1
Chatterjee, S1
Fry, LL1
Ply, JJ1
Roberts, CW1
Krohne, SG1
Gionfriddo, J1
Morrison, EA1
Guzińska, M1
Kałuzny, J1
Florek, G1
Srinivasan, R1
Psilas, K1
Kalogeropoulos, C1
Loucatzicos, E1
Asproudis, I1
Petroutsos, G1
Dimitrakos, SA1
Topouzidis, C1
Panidou-Kyriakidou, I1

Trials

10 trials available for diclofenac and Miosis

ArticleYear
Effect of topical nonsteroidal anti-inflammatory drugs and nuclear hardness on maintenance of mydriasis during phacoemulsification surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:10

    Topics: Administration, Ophthalmic; Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Cataract; Di

2014
NSAID Pretreatment Inhibits Prostaglandin Release in Femtosecond Laser-Assisted Cataract Surgery.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2015, Volume: 31, Issue:12

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous H

2015
Topical administration of diclofenac (1%) in the prevention of miosis during vitrectomy.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:9

    Topics: Administration, Topical; Adult; Aged; Anterior Chamber; Diclofenac; Double-Blind Method; Female; Hum

2008
Clinical study of diclofenac sodium eyedrops used before and after cataract operation.
    Yan ke xue bao = Eye science, 1999, Volume: 15, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Female; Humans; Inflammati

1999
Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery.
    Journal of cataract and refractive surgery, 1995, Volume: 21, Issue:2

    Topics: Administration, Topical; Carbachol; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Lenses, I

1995
Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis.
    Journal of cataract and refractive surgery, 1996, Volume: 22 Suppl 1

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Flurbiprofen;

1996
[The effect of diclofenac sodium and indomethacin used locally for maintenance of pupillary dilatation during cataract surgery].
    Klinika oczna, 1998, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclof

1998
Topical ketorolac tromethamine 0.5% versus diclofenac sodium 0.1% to inhibit miosis during cataract surgery.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; D

2002
The effect of indomethacin, diclofenac and flurbiprofen on the maintenance of mydriasis during extracapsular cataract extraction.
    Documenta ophthalmologica. Advances in ophthalmology, 1992, Volume: 81, Issue:3

    Topics: Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Indomethacin; Intrao

1992
[Prevention of peroperative miosis: comparison between prostaglandin inhibitors. Sodium diclofenac and indomethacin in local application].
    Journal francais d'ophtalmologie, 1992, Volume: 15, Issue:1

    Topics: Cataract Extraction; Diclofenac; Humans; Indomethacin; Intraoperative Complications; Miosis; Ophthal

1992

Other Studies

3 other studies available for diclofenac and Miosis

ArticleYear
Preventing perioperative miosis in cataract surgery.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ketorolac; Miosis; Myd

2003
Decrease of postoperative inflammation with diclofenac sodium.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Acetylcholine; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Drug Combin

1996
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
    American journal of veterinary research, 1998, Volume: 59, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclo

1998