diclofenac has been researched along with Lymphoma, Mantle-Cell in 2 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Lymphoma, Mantle-Cell: A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diclofenac treatment was associated with increased activity of caspases 3, 7, and 8 and induction of p53 transcriptional target genes." | 1.43 | Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status. ( Chaturvedi, NK; Dave, BJ; Hassan, HM; Joshi, SS; Singh, RK; Varney, ML; Weisenburger, DD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ran, F | 1 |
| Liu, Y | 1 |
| Zhang, D | 1 |
| Liu, M | 1 |
| Zhao, G | 1 |
| Hassan, HM | 1 |
| Varney, ML | 1 |
| Chaturvedi, NK | 1 |
| Joshi, SS | 1 |
| Weisenburger, DD | 1 |
| Singh, RK | 1 |
| Dave, BJ | 1 |
2 other studies available for diclofenac and Lymphoma, Mantle-Cell
| Article | Year |
|---|---|
Discovery of novel pyrazole derivatives as potential anticancer agents in MCL.
Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Cell Proliferation; Drug Design; Half-Li | 2019 |
Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status.
Topics: Apoptosis; Caspases; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Diclo | 2016 |