diclofenac has been researched along with Liver Failure in 5 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case report describes fulminant hepatic failure in a 53-year-old female caused by inadvertent rechallenging with diclofenac, treated by orthotopic liver transplantation." | 7.71 | Inadvertent diclofenac rechallenge from generic and non-generic prescribing, leading to liver transplantation for fulminant liver failure. ( Agarwal, A; Burroughs, AK; Davidson, BR; Davies, SE; Greaves, RR; Patch, D; Reynolds, N; Rolles, K; Sherman, D, 2001) |
| "This case report describes fulminant hepatic failure in a 53-year-old female caused by inadvertent rechallenging with diclofenac, treated by orthotopic liver transplantation." | 3.71 | Inadvertent diclofenac rechallenge from generic and non-generic prescribing, leading to liver transplantation for fulminant liver failure. ( Agarwal, A; Burroughs, AK; Davidson, BR; Davies, SE; Greaves, RR; Patch, D; Reynolds, N; Rolles, K; Sherman, D, 2001) |
| "The effect of the acute hepatic failure induced by CCl4 on the pharmacokinetics of diclofenac, which is definitely subject to enterohepatic circulation (EHC) in normal rats, was evaluated." | 3.69 | Influence of laparotomy on disposition kinetics of diclofenac in CCl4-intoxicated rats. ( Fukuyama, T; Nakagawa, T; Tabata, K; Yamaoka, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawasaki, Y | 1 |
| Matsubara, K | 1 |
| Hashimoto, K | 1 |
| Tanigawa, K | 1 |
| Kage, M | 1 |
| Iwata, A | 1 |
| Nigami, H | 1 |
| Fukaya, T | 1 |
| Ceulemans, LJ | 1 |
| De Hertogh, G | 1 |
| Van Cromphaut, S | 1 |
| Vermeire, S | 1 |
| Pirenne, J | 1 |
| Kittisupamongkol, W | 1 |
| Fukuyama, T | 1 |
| Yamaoka, K | 1 |
| Tabata, K | 1 |
| Nakagawa, T | 1 |
| Greaves, RR | 1 |
| Agarwal, A | 1 |
| Patch, D | 1 |
| Davies, SE | 1 |
| Sherman, D | 1 |
| Reynolds, N | 1 |
| Rolles, K | 1 |
| Davidson, BR | 1 |
| Burroughs, AK | 1 |
5 other studies available for diclofenac and Liver Failure
| Article | Year |
|---|---|
Nonsteroidal anti-inflammatory drug-induced vanishing bile duct syndrome treated with plasmapheresis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bile Duct Diseases; Bile Ducts; Diclofenac; Fem | 2013 |
Nonsteroidal anti-inflammatory drug-induced intestinal graft loss 12 years after transplantation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diclofenac; Fatal Outcome; Female; Femoral Vein; Gr | 2015 |
Liver injury from diclofenac or acetaminophen?
Topics: Acetaminophen; Diclofenac; Humans; Liver; Liver Failure; Risk Assessment; Sensitivity and Specificit | 2009 |
Influence of laparotomy on disposition kinetics of diclofenac in CCl4-intoxicated rats.
Topics: Animals; Carbon Tetrachloride Poisoning; Diclofenac; Laparotomy; Liver Failure; Male; Rats; Rats, Wi | 1995 |
Inadvertent diclofenac rechallenge from generic and non-generic prescribing, leading to liver transplantation for fulminant liver failure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drugs, Generic; Female; Humans; Liver Failure; | 2001 |