diclofenac has been researched along with Liver Failure, Acute in 4 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, some patients may develop acute liver failure and successful orthotopic liver transplantation may be undertaken in such patients." | 2.42 | Hepatocellular damage from non-steroidal anti-inflammatory drugs. ( Dargan, PI; Jones, AL; O'Connor, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alhaddad, O | 1 |
| Elsabaawy, M | 1 |
| Abdelsameea, E | 1 |
| Abdallah, A | 1 |
| Shabaan, A | 1 |
| Ehsan, N | 1 |
| Elrefaey, A | 1 |
| Elsabaawy, D | 1 |
| Salama, M | 1 |
| Audimoolam, VK | 1 |
| Wendon, J | 1 |
| Bernal, W | 1 |
| Heaton, N | 1 |
| O'Grady, J | 1 |
| Auzinger, G | 1 |
| O'Connor, N | 1 |
| Dargan, PI | 1 |
| Jones, AL | 1 |
| Björnsson, E | 1 |
| Jerlstad, P | 1 |
| Bergqvist, A | 1 |
| Olsson, R | 1 |
1 review available for diclofenac and Liver Failure, Acute
| Article | Year |
|---|---|
Hepatocellular damage from non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; D | 2003 |
3 other studies available for diclofenac and Liver Failure, Acute
| Article | Year |
|---|---|
Presentations, Causes and Outcomes of Drug-Induced Liver Injury in Egypt.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amoxicillin-Potassium Clavulanate Combination; An | 2020 |
Iron and acetaminophen a fatal combination?
Topics: Accidents; Acetaminophen; Adolescent; Adult; Biopsy; Brain; Diclofenac; Drug Overdose; Female; Human | 2011 |
Fulminant drug-induced hepatic failure leading to death or liver transplantation in Sweden.
Topics: Acetaminophen; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; | 2005 |