diclofenac has been researched along with Leukemia, Myeloid, Acute in 2 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Finally, we tested the effect of the anti-inflammation drug diclofenac on leukemia mice." | 3.88 | Leukemia cells impair normal hematopoiesis and induce functionally loss of hematopoietic stem cells through immune cells and inflammation. ( Cui, M; Cui, P; Gao, J; Huang, S; Li, Z; Ma, G; Wang, N; Wang, R; Zhang, Y, 2018) |
| "Acute myeloid leukemia is a heterogeneous disease with varying genetic and molecular pathologies." | 1.37 | The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway. ( Brünnert, D; Bruns, I; Cadeddu, RP; Czibere, A; Fröbel, J; Haas, R; Hartwig, S; Lehr, S; Prenzel, T; Schroeder, T; Singh, R; Wilk, CM; Zerbini, LF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, P | 1 |
| Zhang, Y | 1 |
| Cui, M | 1 |
| Li, Z | 1 |
| Ma, G | 1 |
| Wang, R | 1 |
| Wang, N | 1 |
| Huang, S | 1 |
| Gao, J | 1 |
| Singh, R | 1 |
| Cadeddu, RP | 1 |
| Fröbel, J | 1 |
| Wilk, CM | 1 |
| Bruns, I | 1 |
| Zerbini, LF | 1 |
| Prenzel, T | 1 |
| Hartwig, S | 1 |
| Brünnert, D | 1 |
| Schroeder, T | 1 |
| Lehr, S | 1 |
| Haas, R | 1 |
| Czibere, A | 1 |
2 other studies available for diclofenac and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Leukemia cells impair normal hematopoiesis and induce functionally loss of hematopoietic stem cells through immune cells and inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coculture Techniques; Diclofenac; Hematopoiesis; H | 2018 |
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Differentia | 2011 |