diclofenac has been researched along with Joint Pain in 39 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To measure the efficacy and safety of diclofenac sodium gel in patients with primary hand osteoarthritis (OA)." | 9.14 | Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial. ( Altman, RD; Chase, WF; Dreher, DS; Dreiser, RL; Fisher, CL; Zacher, J, 2009) |
| " This safety study compared the GI tolerability, the blood pressure (BP) profile and the incidence of oedema with lumiracoxib and rofecoxib in the treatment of OA." | 9.13 | A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. ( Krammer, G; Stricker, K; Yu, S, 2008) |
| " Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis." | 9.10 | Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003) |
| "The efficacy and tolerability of a new resinate formulation of diclofenac 75mg taken once or twice daily were compared with that of conventional enteric-coated diclofenac sodium 50mg tablets given two or three times daily in a double-blind, randomised, between-patient, 12-week trial in 216 adult patients suffering from painful osteoarthritis of the hip and/or knee." | 9.08 | Comparative efficacy and tolerability of two diclofenac formulations in the treatment of painful osteoarthritis. ( Bakshi, R, 1996) |
| "Joint pain decreased after 2 weeks of therapy in all patients during treatment with Voltaren Emulgel 2% (diclofenac diethylamine 2%) in both groups." | 8.02 | [Evaluation of topical therapy of patients with osteoarthritis of small joints of the hands with Voltaren® Emulgel® 2% (diclofenac diethylamine 2%)]. ( Gromova, MA; Tsurko, VV, 2021) |
| "To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain." | 8.02 | Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021) |
| "A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated." | 7.70 | [Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999) |
| "Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test." | 5.38 | Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012) |
| "osteoarthritis of knee compared to 1% diclofenac gel as an active control." | 5.24 | A Comparative of Ginger Extract in Nanostructure Lipid Carrier (NLC) and 1% Diclofenac Gel for Treatment of Knee Osteoarthritis (OA). ( Amorndoljai, P; Niempoog, S; Nimmannit, U; Taneepanichskul, S, 2017) |
| "To measure the efficacy and safety of diclofenac sodium gel in patients with primary hand osteoarthritis (OA)." | 5.14 | Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial. ( Altman, RD; Chase, WF; Dreher, DS; Dreiser, RL; Fisher, CL; Zacher, J, 2009) |
| " This safety study compared the GI tolerability, the blood pressure (BP) profile and the incidence of oedema with lumiracoxib and rofecoxib in the treatment of OA." | 5.13 | A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. ( Krammer, G; Stricker, K; Yu, S, 2008) |
| " Twenty-five patients with acute gout arthritis were randomized into two groups and treated over 5 days: group A, diclofenac 75 mg orally, twice a day; and group B, laser irradiation once a day." | 5.12 | Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results. ( Campana, V; Gavotto, A; Moya, M; Palma, J; Simes, J; Soriano, F; Soriano, M; Soriano, R; Spitale, L, 2006) |
| " Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis." | 5.10 | Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003) |
| "The efficacy and tolerability of a new resinate formulation of diclofenac 75mg taken once or twice daily were compared with that of conventional enteric-coated diclofenac sodium 50mg tablets given two or three times daily in a double-blind, randomised, between-patient, 12-week trial in 216 adult patients suffering from painful osteoarthritis of the hip and/or knee." | 5.08 | Comparative efficacy and tolerability of two diclofenac formulations in the treatment of painful osteoarthritis. ( Bakshi, R, 1996) |
| " An increased risk of acute myocardial infarction and heart failure is observed with all NSAIDs, while an elevated risk of hemorrhagic stroke appears to be restricted to the use of diclofenac and meloxicam." | 5.01 | Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say? ( Al-Daghri, N; Bruyère, O; Chapurlat, R; Cooper, C; Herrero-Beaumont, G; Rannou, F; Reginster, JY; Roth, R; Uebelhart, D, 2019) |
| " A diagnosis of ochronosis was made by the observation of bluish-brown pigmentation in the nose and ears, dark urine colors following alkalization, and high levels of homogentisic acid in the urine." | 4.84 | Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature. ( Capkin, E; Karkucak, M; Serdaroğlu, M; Tosun, M; Yayli, S, 2007) |
| "Joint pain decreased after 2 weeks of therapy in all patients during treatment with Voltaren Emulgel 2% (diclofenac diethylamine 2%) in both groups." | 4.02 | [Evaluation of topical therapy of patients with osteoarthritis of small joints of the hands with Voltaren® Emulgel® 2% (diclofenac diethylamine 2%)]. ( Gromova, MA; Tsurko, VV, 2021) |
| "To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain." | 4.02 | Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021) |
| "A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated." | 3.70 | [Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999) |
| " Observation indicators included: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Hospital for Special Surgery Knee Score (HSS), liver and kidney function, adverse reactions, and so on." | 3.01 | Efficacy and safety of Biqi capsule in the treatment of knee osteoarthritis: A protocol of a randomized controlled trial. ( Huang, H; Jia, M; Tian, K; Wang, W; Zhou, Y, 2021) |
| " Any observed adverse effects were also scrutinized." | 2.82 | Efficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis: A randomized, double-blind, active-controlled trial. ( Emtiazy, M; Hashempur, MH; Jabbari, M; Kamalinejad, M; Razavi, SZ; Shahraki, HR, 2016) |
| "Knee osteoarthritis is one of the most prevalent chronic disorders." | 2.80 | Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee. ( Dehghan, M, 2015) |
| "Acute ankle sprains are common and activity limiting injuries, and topical diclofenac gel has proven efficacy in alleviating pain and restoring function." | 2.78 | Traumeel vs. diclofenac for reducing pain and improving ankle mobility after acute ankle sprain: a multicentre, randomised, blinded, controlled and non-inferiority trial. ( González de Vega, C; González, J; Speed, C; Wolfarth, B, 2013) |
| " The commonest adverse event associated with TDiclo was dry skin (18." | 2.74 | Efficacy and safety of topical diclofenac containing dimethyl sulfoxide (DMSO) compared with those of topical placebo, DMSO vehicle and oral diclofenac for knee osteoarthritis. ( Bookman, AAM; Grierson, LM; Naseer, Z; Shainhouse, ZJ; Simon, LS, 2009) |
| "The incidence of gastrointestinal disorders was 5." | 2.74 | Randomized controlled trial of diclofenac sodium gel in knee osteoarthritis. ( Altman, RD; Barthel, HR; Gold, MS; Haselwood, D; Longley, S, 2009) |
| "diclofenac (n = 131) were assessed in a multicentre, randomised, double-blind study of a mixed population of patients with osteoarthritis of the knee and/or hip." | 2.69 | Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac. ( Dirschedl, H; Fürst, M; Gimbel, W; Herrmann, G; Hildebrandt, HD; Jungmichel, D; Klasser, M; Parnham, MJ; Rohde, H; Steeger, D; Venbrocks, R; Wirbitzky, J, 2000) |
| " Despite the many available forms of NSAIDs, including injectable as well as topical, oral dosing is the most common route, usually the one route consistently associated with chronic use and thus the one that carries the most risk." | 1.39 | Nonsteroidal anti-inflammatory drugs and their risk: a story still in development. ( Simon, LS, 2013) |
| "Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test." | 1.38 | Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 16 (41.03) | 24.3611 |
| 2020's | 5 (12.82) | 2.80 |
| Authors | Studies |
|---|---|
| Tsurko, VV | 1 |
| Gromova, MA | 1 |
| Nishida, Y | 1 |
| Kano, K | 1 |
| Nobuoka, Y | 1 |
| Seo, T | 1 |
| Tartaglia, GM | 1 |
| Gizdulich, A | 1 |
| Farronato, M | 1 |
| Gupta, RJ | 1 |
| Connelly, ST | 1 |
| Zhou, Y | 1 |
| Wang, W | 1 |
| Tian, K | 1 |
| Huang, H | 1 |
| Jia, M | 1 |
| Ventura-Martínez, R | 1 |
| Déciga-Campos, M | 1 |
| Bustamante-Marquina, A | 1 |
| Ángeles-López, GE | 1 |
| Aviles-Herrera, J | 1 |
| González-Trujano, ME | 1 |
| Navarrete-Vázquez, G | 1 |
| Sivordova, LE | 1 |
| Zavodovsky, BV | 1 |
| Polyakova, JV | 1 |
| Akhverdyan, YR | 1 |
| Krabansky, F | 1 |
| Azzouz, B | 1 |
| Biya, J | 1 |
| Abou Taam, M | 1 |
| Morel, A | 1 |
| Trenque, T | 1 |
| Amorndoljai, P | 1 |
| Taneepanichskul, S | 1 |
| Niempoog, S | 1 |
| Nimmannit, U | 1 |
| Ter Heegde, F | 1 |
| Luiz, AP | 1 |
| Santana-Varela, S | 1 |
| Chessell, IP | 1 |
| Welsh, F | 1 |
| Wood, JN | 1 |
| Chenu, C | 1 |
| Cooper, C | 1 |
| Chapurlat, R | 1 |
| Al-Daghri, N | 1 |
| Herrero-Beaumont, G | 1 |
| Bruyère, O | 1 |
| Rannou, F | 1 |
| Roth, R | 1 |
| Uebelhart, D | 1 |
| Reginster, JY | 2 |
| Jensen, MP | 1 |
| Molton, IR | 1 |
| González de Vega, C | 1 |
| Speed, C | 1 |
| Wolfarth, B | 1 |
| González, J | 1 |
| Simon, LS | 2 |
| Vaishya, R | 1 |
| Vijay, V | 1 |
| Vaish, A | 1 |
| Dehghan, M | 1 |
| Jabbari, M | 1 |
| Hashempur, MH | 1 |
| Razavi, SZ | 1 |
| Shahraki, HR | 1 |
| Kamalinejad, M | 1 |
| Emtiazy, M | 1 |
| Stricker, K | 1 |
| Yu, S | 1 |
| Krammer, G | 1 |
| Grierson, LM | 1 |
| Naseer, Z | 1 |
| Bookman, AAM | 1 |
| Shainhouse, ZJ | 1 |
| Altman, RD | 2 |
| Dreiser, RL | 2 |
| Fisher, CL | 1 |
| Chase, WF | 1 |
| Dreher, DS | 1 |
| Zacher, J | 1 |
| Barthel, HR | 1 |
| Haselwood, D | 1 |
| Longley, S | 1 |
| Gold, MS | 1 |
| Verkleij, SP | 1 |
| Luijsterburg, PA | 1 |
| Koes, BW | 1 |
| Bohnen, AM | 1 |
| Bierma-Zeinstra, SM | 1 |
| Schuelert, N | 1 |
| Johnson, MP | 1 |
| Oskins, JL | 1 |
| Jassal, K | 1 |
| Chambers, MG | 1 |
| McDougall, JJ | 1 |
| Singh, K | 1 |
| Sharma, R | 1 |
| Rai, J | 1 |
| Ferreira-Gomes, J | 1 |
| Adães, S | 1 |
| Mendonça, M | 1 |
| Castro-Lopes, JM | 1 |
| Bas, DB | 1 |
| Su, J | 1 |
| Sandor, K | 1 |
| Agalave, NM | 1 |
| Lundberg, J | 1 |
| Codeluppi, S | 1 |
| Baharpoor, A | 1 |
| Nandakumar, KS | 1 |
| Holmdahl, R | 1 |
| Svensson, CI | 1 |
| Montoro, J | 1 |
| Rodríguez, M | 1 |
| Díaz, M | 1 |
| Bertomeu, F | 1 |
| Duffy, T | 1 |
| Belton, O | 1 |
| Bresnihan, B | 1 |
| FitzGerald, O | 1 |
| FitzGerald, D | 1 |
| Soriano, F | 1 |
| Campana, V | 1 |
| Moya, M | 1 |
| Gavotto, A | 1 |
| Simes, J | 1 |
| Soriano, M | 1 |
| Soriano, R | 1 |
| Spitale, L | 1 |
| Palma, J | 1 |
| Brühlmann, P | 1 |
| de Vathaire, F | 1 |
| Michel, BA | 1 |
| Capkin, E | 1 |
| Karkucak, M | 1 |
| Yayli, S | 1 |
| Serdaroğlu, M | 1 |
| Tosun, M | 1 |
| Fleischmann, R | 1 |
| Tannenbaum, H | 1 |
| Patel, NP | 1 |
| Notter, M | 1 |
| Sallstig, P | 1 |
| Bakshi, R | 1 |
| Tsujimura, M | 1 |
| Yamaji, K | 1 |
| Tokano, Y | 1 |
| Sugawara, M | 1 |
| Kobayashi, S | 1 |
| Takasaki, Y | 1 |
| Hashimoto, H | 1 |
| Hirose, S | 1 |
| Lecoules, S | 1 |
| Duvic, C | 1 |
| Hérody, M | 1 |
| Nédélec, G | 1 |
| Bauer, HW | 1 |
| Klasser, M | 2 |
| von Hanstein, KL | 1 |
| Rolinger, H | 1 |
| Schladitz, G | 1 |
| Henke, HD | 1 |
| Gimbel, W | 2 |
| Steinbach, K | 1 |
| Pai, S | 1 |
| Balasubramanian, R | 1 |
| Shenoi, S | 1 |
| Sandra, A | 1 |
| Enrique, E | 1 |
| Cisteró-Bahima, A | 1 |
| Alonso, R | 1 |
| Bravo, P | 1 |
| Fenollosa, A | 1 |
| Torre, I | 1 |
| Herrmann, G | 1 |
| Steeger, D | 1 |
| Wirbitzky, J | 1 |
| Fürst, M | 1 |
| Venbrocks, R | 1 |
| Rohde, H | 1 |
| Jungmichel, D | 1 |
| Hildebrandt, HD | 1 |
| Parnham, MJ | 1 |
| Dirschedl, H | 1 |
| Sangdee, C | 1 |
| Teekachunhatean, S | 1 |
| Sananpanich, K | 1 |
| Sugandhavesa, N | 1 |
| Chiewchantanakit, S | 1 |
| Pojchamarnwiputh, S | 1 |
| Jayasvasti, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled, Multi-center Study on the Effectiveness of Traumeel S (Both Ointment and Gel) in Terms of Pain and Function Compared With a Topical NSAID in Athletes With Acute Ankle Sprain[NCT01066520] | Phase 3 | 449 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| The Effect of Chronic Pain Relief Over Knee Joint Area by Gua Sha Therapy[NCT03821194] | 40 participants (Anticipated) | Interventional | 2019-01-25 | Recruiting | |||
| Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment) | ||
| A 6-Week Multicenter, Randomized, Double-Blind, Double-Dummy, Active-Controlled Parallel Group Clinical Saftey Study to Evaluate Incidence of Predefined Gastrointestinal Adverse Events and Peripheral Edema in Subjects With Primary Osteoarthritis Treated W[NCT00637949] | Phase 3 | 309 participants (Actual) | Interventional | 2000-12-31 | Completed | ||
| Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis[NCT00171665] | Phase 3 | 360 participants | Interventional | 2005-05-31 | Completed | ||
| The Effect of St. John's Wort Oil on Pain Intensity and Physical Functions in People With Knee Osteoarthritis: a Qualitative and Randomized Placebo-controlled Trial[NCT05663996] | 60 participants (Actual) | Interventional | 2017-12-25 | Completed | |||
| Osteoarthritis of the Knee Pain Study Using CBD and THC in Rapidly Dissolvable Sublingual Tablet[NCT04195269] | Phase 2 | 30 participants (Anticipated) | Interventional | 2020-04-20 | Recruiting | ||
| A 52-week, International, Multi-center, Randomized, Double-blind, Double-dummy, Parallel-group Clinical Trial to Compare Retention on Treatment, Safety, Tolerability and Efficacy of Lumiracoxib 100 mg od, Lumiracoxib 100 mg Bid and Celecoxib 200 mg od in [NCT00145301] | Phase 3 | 3,036 participants | Interventional | 2004-09-30 | Completed | ||
| Randomized, Double-Blind, Placebo-Controlled Trial, Parallel Design Used To Evaluate Pain, Endocrinologic Variations, Life Quality And Medication Use, After Electro-Acupuncture Treatment In Patients With Osteoarthritis Of The Knee[NCT02299713] | 160 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The Foot and Ankle Ability Measure (FAAM) is a self-report outcome instrument developed to assess physical function for individuals with foot and ankle related impairments. The Foot and Ankle Ability Measure is a 29-item questionnaire divided into two subscales: the Foot and Ankle Ability Measure, 21-item Activities of Daily Living Subscale and the Foot and Ankle Ability Measure, 8-item Sports Subscale.~Each item is scored on a 5-point Likert scale (4 to 0) from 'no difficulty at all' (score 4), ´slight difficulty´, ´moderate difficulty´, éxtreme difficulty´ to 'unable to do' (score 0). Responses marked as ´not applicable´were not counted.~Item score totals, which range from 0 to 84 for the ADL subscale and 0 to 32 for the Sports subscale, were transformed to percentage scores. Higher scores represent higher levels of function for each subscale, with 100% representing no dysfunction." (NCT01066520)
Timeframe: Day 1 to day 7
| Intervention | Scores on a scale (Median) |
|---|---|
| Traumeel S Ointment | 26.20 |
| Traumeel S Gel | 26.20 |
| Diclofenac Gel | 25.00 |
"Pain evaluated by a 100 mm visual analogue scale (VAS) where 0 means no pain and 100 means the highest, unbearable pain. The absolute values of VAS have been the basis of analysis.~The highest is the change in negative, the better are the results in absolute values." (NCT01066520)
Timeframe: From baseline (day 1) visit to day 7
| Intervention | Absolute value units on a scale VAS (Median) |
|---|---|
| Traumeel S Ointment | -33.00 |
| Traumeel S Gel | -37.10 |
| Diclofenac Gel | -37.10 |
"Pain evaluated by a 100 mm visual analogue scale (VAS) where 0 means no pain and 100 means the highest, unbearable pain. The absolute values of VAS have been the basis of analysis.~The highest is the change in negative, the better are the results in percentages." (NCT01066520)
Timeframe: From baseline (day 1) visit to day 7
| Intervention | Percentage change in scale VAS (Median) |
|---|---|
| Traumeel S Ointment | -60.55 |
| Traumeel S Gel | -71.10 |
| Diclofenac Gel | -68.90 |
3 reviews available for diclofenac and Joint Pain
| Article | Year |
|---|---|
Eosinophilic pneumonia induced by non-steroidal anti-inflammatory drugs: An underestimated risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Female; Humans; Middle Aged; Pharma | 2018 |
Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Gastrointestinal Diseases; Humans; | 2019 |
Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature.
Topics: Alkaptonuria; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Ascorbic Acid; Back Pain; Calcino | 2007 |
23 trials available for diclofenac and Joint Pain
| Article | Year |
|---|---|
Sustained-release diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate) for knee osteoarthritis: a randomized phase 2 study.
Topics: Aged; Arthralgia; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Female; Humans; Hyal | 2021 |
Electroporation technique for joint pain - Pilot feasibility study on TMD patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Electrochemotherapy; F | 2020 |
Efficacy and safety of Biqi capsule in the treatment of knee osteoarthritis: A protocol of a randomized controlled trial.
Topics: Adult; Arthralgia; Capsules; Delayed-Action Preparations; Diclofenac; Drug Therapy, Combination; Dru | 2021 |
[Evidence of feasibility etoricoxib therapy in osteoarthritis in elderly patients].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Drug Monit | 2016 |
A Comparative of Ginger Extract in Nanostructure Lipid Carrier (NLC) and 1% Diclofenac Gel for Treatment of Knee Osteoarthritis (OA).
Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Doub | 2017 |
The reciprocal effects of pain intensity and activity limitations: implications for outcomes assessment in clinical trials.
Topics: Activities of Daily Living; Adult; Analgesics; Arthralgia; Clinical Trials as Topic; Diclofenac; Fem | 2014 |
Traumeel vs. diclofenac for reducing pain and improving ankle mobility after acute ankle sprain: a multicentre, randomised, blinded, controlled and non-inferiority trial.
Topics: Acute Disease; Administration, Cutaneous; Adolescent; Adult; Analgesics; Ankle Injuries; Anti-Inflam | 2013 |
Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Double-Blind Method; Drug Th | 2015 |
Efficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis: A randomized, double-blind, active-controlled trial.
Topics: Administration, Cutaneous; Adult; Analgesics; Arthralgia; Cyclooxygenase Inhibitors; Diclofenac; Dou | 2016 |
A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients.
Topics: Aged; Arthralgia; Blood Pressure; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationshi | 2008 |
Efficacy and safety of topical diclofenac containing dimethyl sulfoxide (DMSO) compared with those of topical placebo, DMSO vehicle and oral diclofenac for knee osteoarthritis.
Topics: Activities of Daily Living; Administration, Oral; Administration, Topical; Aged; Anti-Inflammatory A | 2009 |
Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Dou | 2009 |
Randomized controlled trial of diclofenac sodium gel in knee osteoarthritis.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Arthralgia; Diclofenac; Female; Gastrointes | 2009 |
Effectiveness of diclofenac versus acetaminophen in primary care patients with knee osteoarthritis: [NTR1485], DIPA-trial: design of a randomized clinical trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; | 2010 |
Diacerein as adjuvant to diclofenac sodium in osteoarthritis knee.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anthraquinones; Anti-Inflammatory Age | 2012 |
Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis.
Topics: Acute Disease; Administration, Oral; Arthralgia; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Dicl | 2003 |
Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.
Topics: Animals; Arthralgia; Arthritis, Experimental; Biomarkers; Calcium Pyrophosphate; Diclofenac; Dinopro | 2006 |
Long-term retention on treatment with lumiracoxib 100 mg once or twice daily compared with celecoxib 200 mg once daily: a randomised controlled trial in patients with osteoarthritis.
Topics: Aged; Arthralgia; Canada; Cardiovascular Diseases; Celecoxib; Chemical and Drug Induced Liver Injury | 2008 |
Comparative efficacy and tolerability of two diclofenac formulations in the treatment of painful osteoarthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Double-Bli | 1996 |
Oxaceprol is as effective as diclofenac in the therapy of osteoarthritis of the knee and hip.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthr | 1999 |
Diclofenac-induced fever.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chlorpheniramine; Diclofenac; Drug Hypers | 2000 |
Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Double-Blind Method; Female; Humans | 2000 |
Electroacupuncture versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Com | 2002 |
13 other studies available for diclofenac and Joint Pain
| Article | Year |
|---|---|
[Evaluation of topical therapy of patients with osteoarthritis of small joints of the hands with Voltaren® Emulgel® 2% (diclofenac diethylamine 2%)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Female; Humans; Male; Osteoarthriti | 2021 |
Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis; Diclofenac; Dis | 2021 |
Noninvasive Mechanical Joint Loading as an Alternative Model for Osteoarthritic Pain.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Behavior, Animal; Cartilag | 2019 |
Nonsteroidal anti-inflammatory drugs and their risk: a story still in development.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Cardiovascular Diseases; | 2013 |
Spontaneous osteonecrosis of the knee: an unusual cause of knee pain.
Topics: Acute Disease; Adult; Alendronate; Arthralgia; Diclofenac; Disease Progression; Humans; Knee Joint; | 2014 |
Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis.
Topics: Action Potentials; Afferent Pathways; Age Factors; Animals; Arthralgia; Benzamides; Carbamates; Dicl | 2011 |
Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis.
Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Diclofenac; Disease Models, Animal; Injection | 2012 |
Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.
Topics: Amines; Analgesics; Animals; Arthralgia; Arthritis, Experimental; Buprenorphine; Cyclohexanecarboxyl | 2012 |
Photoallergic contact dermatitis due to diclofenac.
Topics: Administration, Topical; Adult; Allergens; Arthralgia; Dermatitis, Photoallergic; Diclofenac; Elbow | 2003 |
Short-term treatment with topical diclofenac epolamine plaster in patients with symptomatic knee osteoarthritis: pooled analysis of two randomised clinical studies.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-S | 2006 |
[A case of reactive arthritis fallen after shigellosis infection].
Topics: Adult; Anti-Inflammatory Agents; Arthralgia; Arthritis, Reactive; Biomarkers; Diclofenac; Dysentery, | 1997 |
[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Diclofenac; Dose-R | 1999 |
Clearance of psoriasis following agranulocytosis.
Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Humans; Male; Midd | 1999 |