diclofenac has been researched along with Itching in 9 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this prospective randomised study, pruritus and pain were evaluated in patients undergoing abdominal surgery in which intrathecal morphine was administered." | 9.09 | The effect of rectal diclofenac on pruritus in patients receiving intrathecal morphine. ( Chambers, F; Colbert, S; Galvin, S; Moriarty, DC; O'Hanlon, DM, 1999) |
| "In this prospective randomised study, pruritus and pain were evaluated in patients undergoing abdominal surgery in which intrathecal morphine was administered." | 5.09 | The effect of rectal diclofenac on pruritus in patients receiving intrathecal morphine. ( Chambers, F; Colbert, S; Galvin, S; Moriarty, DC; O'Hanlon, DM, 1999) |
| " In this study, a very small dose of intrathecal morphine, in association with intramuscular diclofenac, proved effective for controlling pain after cesarean delivery, with a low incidence of morphine-induced pruritus." | 5.08 | Small doses of intrathecal morphine combined with systemic diclofenac for postoperative pain control after cesarean delivery. ( Amaro, AR; Cappelli, EL; Cardoso, MM; Carvalho, JC; Prado, AA, 1998) |
| "The patient also presented an immediate hypersensitivity reaction after taking diclofenac." | 1.35 | Systemic dermatitis due to tetrazepam. ( Laguna-Martínez, JJ; Reaño-Martos, M; Rojo-Andrés, E; Sánchez-Morillas, L; Ubeda, PG, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sánchez-Morillas, L | 1 |
| Laguna-Martínez, JJ | 1 |
| Reaño-Martos, M | 1 |
| Rojo-Andrés, E | 1 |
| Ubeda, PG | 1 |
| Kanazi, GE | 1 |
| Aouad, MT | 1 |
| Abdallah, FW | 1 |
| Khatib, MI | 1 |
| Adham, AM | 1 |
| Harfoush, DW | 1 |
| Siddik-Sayyid, SM | 1 |
| Moisseiev, E | 1 |
| Varssano, D | 1 |
| Hashimoto, T | 1 |
| Igarashi, A | 1 |
| Hoshina, F | 1 |
| Yamada, M | 1 |
| Toyoda, Y | 1 |
| Notsu, Y | 1 |
| Kohno, S | 1 |
| Wrench, IJ | 1 |
| Sanghera, S | 1 |
| Pinder, A | 1 |
| Power, L | 1 |
| Adams, MG | 1 |
| Moriarty, A | 1 |
| Cardoso, MM | 1 |
| Carvalho, JC | 1 |
| Amaro, AR | 1 |
| Prado, AA | 1 |
| Cappelli, EL | 1 |
| Colbert, S | 1 |
| O'Hanlon, DM | 1 |
| Galvin, S | 1 |
| Chambers, F | 1 |
| Moriarty, DC | 1 |
| del Pozo, MD | 1 |
| Lobera, T | 1 |
| Blasco, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Transversus Abdominis Plane Block Versus Quadratus Lumborum Technique in Patients After Cesarean Section[NCT02804126] | Phase 4 | 232 participants (Actual) | Interventional | 2017-06-01 | Completed | ||
| The Postoperative Analgesic Efficacy of Varied Concentrations of Ropivacaine Used for the Transverse Abdominis Plane (TAP) Block After Cesarean Delivery[NCT01170702] | Phase 4 | 120 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 0-24 hours after completion of the TAP block. (NCT01170702)
Timeframe: 24 hours
| Intervention | Morphine equivalents (mg) (Median) |
|---|---|
| Group 1 | 54 |
| Group 2 | 38 |
| Group 3 | 32 |
| Group 4 | 45 |
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 24-72 hours after completion of the TAP block. (NCT01170702)
Timeframe: 24-72 hours
| Intervention | Morphine equivalents (mgs) (Median) |
|---|---|
| Group 1 | 67 |
| Group 2 | 60 |
| Group 3 | 67 |
| Group 4 | 67 |
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 0-72 hours after completion of the TAP block. (NCT01170702)
Timeframe: 72 hours
| Intervention | Morphine equivalents (mgs) (Median) |
|---|---|
| Group 1 | 120 |
| Group 2 | 96 |
| Group 3 | 98 |
| Group 4 | 112 |
Pain burden at rest calculated as area under the pain score * time (hr) curve 0-72 hours. (NCT01170702)
Timeframe: 72 hours
| Intervention | score on scale * (hr) (Median) |
|---|---|
| Group 1 | 129 |
| Group 2 | 79 |
| Group 3 | 79 |
| Group 4 | 151 |
Pain burden with movement calculated as area under the pain score * time (hr) curve 0-72 hours. (NCT01170702)
Timeframe: 72 hours
| Intervention | pain score * time (hr) curve 72 hours (Median) |
|---|---|
| Group 1 | 265 |
| Group 2 | 202 |
| Group 3 | 233 |
| Group 4 | 327 |
The elapsed time in minutes of the first PCA (patient controlled analgesia) request in time (minutes) from the end of the TAP block. (NCT01170702)
Timeframe: Elapsed time in minutes
| Intervention | Minutes (Mean) |
|---|---|
| Group 1 | 90 |
| Group 2 | 118 |
| Group 3 | 126 |
| Group 4 | 83 |
Pain scores at rest ( 0 low 10 high) using an 11 point VRS (verbal pain scale) at the following hour time points, at the first request for patient controlled analgesia (PCA) then at 2,6,24,and 74 hours after the first request for PCA (patient controlled analgesia). (NCT01170702)
Timeframe: Request for first patient controlled analgesia then at 2,6,24,72 hours after initial PCA request
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| At first PCA request | 2 hous after first PCA request | 6 hours after first PCA request | 24 hours after first PCA request | 72 hours after first PCA reqest | |
| Group 1 | 3 | 3 | 3 | 2 | 1 |
| Group 2 | 3 | 1 | 2 | 1 | .5 |
| Group 3 | 2 | 0 | 2 | 1 | 1 |
| Group 4 | 2 | 2 | 2 | 3 | 1 |
Pain scores with movement ( 0 low 10 high) using an 11 point VRS (verbal pain scale) at the first request for patient controlled analgesia (PCA) then at 2,6,24,and 74 hours after the first request for PCA (patient controlled analgesia). (NCT01170702)
Timeframe: First PCA request then at 2,6,24,72 hours after first PCA request.
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| At first PCA request | 2 hous after first PCA request | 6 hours after first PCA request | 24 hours after first PCA request | 72 hours after first PCA reqest | |
| Group 1 | 5 | 4 | 4 | 4 | 3.5 |
| Group 2 | 3.5 | 2 | 4 | 3 | 2 |
| Group 3 | 3.5 | 3 | 5 | 4 | 3 |
| Group 4 | 4 | 3 | 4 | 5 | 4 |
5 trials available for diclofenac and Itching
| Article | Year |
|---|---|
The analgesic efficacy of subarachnoid morphine in comparison with ultrasound-guided transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesic | 2010 |
Comparison of ocular tolerability between preserved and preservative-free diclofenac sodium drops.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Middle Aged; Ophth | 2011 |
Dose response to intrathecal diamorphine for elective caesarean section and compliance with a national audit standard.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroida | 2007 |
Small doses of intrathecal morphine combined with systemic diclofenac for postoperative pain control after cesarean delivery.
Topics: Cesarean Section; Diclofenac; Female; Humans; Injections, Spinal; Morphine; Nausea; Pain, Postoperat | 1998 |
The effect of rectal diclofenac on pruritus in patients receiving intrathecal morphine.
Topics: Abdomen; Administration, Rectal; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 1999 |
4 other studies available for diclofenac and Itching
| Article | Year |
|---|---|
Systemic dermatitis due to tetrazepam.
Topics: Administration, Oral; Benzodiazepines; Contracture; Dermatitis, Contact; Diclofenac; Drug Hypersensi | 2008 |
Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzophenones; | 2003 |
Use of Ropivacaine in postoperative infusions.
Topics: Abdomen; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agen | 1997 |
Selective hypersensitivity to diclofenac.
Topics: Adult; Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity | 2000 |