Page last updated: 2024-10-26

diclofenac and Intraocular Pressure

diclofenac has been researched along with Intraocular Pressure in 51 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes."9.34Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020)
"To evaluate the comparative effects and safety of topical diclofenac sodium, fluorometholone, and dexamethasone for controlling inflammation after routine strabismus surgery."9.27A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery. ( Bae, S; Choi, DC; Choi, DG; Kim, J; Lee, JY, 2018)
"Intravitreal diclofenac is effective in the treatment of diffuse diabetic macular edema up to 12 weeks."9.15Intravitreal diclofenac versus intravitreal triamcinolone acetonide in the treatment of diabetic macular edema. ( Elbendary, AM; Shahin, MM, 2011)
"VA in both the diclofenac- and betamethasone-treated eyes significantly improved following the cataract surgery; however, no statistical difference of VA was noted between the diclofenac- and betamethasone-treated eyes throughout the observational period (before and after the surgery until 8 weeks postoperatively)."9.12Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes. ( Nakazawa, T; Nishida, K; Shimura, M; Yasuda, K, 2007)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."9.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)
"Latanoprost therapy enhances disruption of the blood-aqueous barrier and increases the incidence of angiographic CME formation in early postoperative pseudophakias."9.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
"To evaluate effects of topical ophthalmic administration of diclofenac on intraocular pressure (IOP) when applied at 4 frequencies to eyes of Beagles."7.96Effect of topical administration of 0.1% diclofenac sodium ophthalmic solution at four frequencies on intraocular pressure in healthy Beagles. ( Colussi, JA; Henriksen, ML; Lappin, MR; Martabano, BB; Sharp, JL; Wang, Z, 2020)
"To evaluate the effect of a single dose of intravitreal diclofenac on macular edema (ME) due to branch retinal vein occlusion (BRVO)."7.83Intravitreal Diclofenac in the Treatment of Macular Edema Due to Branch Retinal Vein Occlusion. ( Arora, S; Ghosh, B; Gupta, A; Raina, UK; Seth, A, 2016)
"Forty-two diabetic patients and 50 normal control patients who underwent small-incision phacoemulsification cataract surgery bilaterally received topical preservative-free diclofenac in 1 eye and preserved diclofenac in the other eye."7.78A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy. ( Miyazawa, A; Shimura, M; Yasuda, K, 2012)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."7.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)
"Diclofenac was more effective than betamethasone in preventing angiographic CME and BAB disruption after small-incision cataract surgery."6.73Reducing angiographic cystoid macular edema and blood-aqueous barrier disruption after small-incision phacoemulsification and foldable intraocular lens implantation: multicenter prospective randomized comparison of topical diclofenac 0.1% and betamethason ( Asano, S; Kimura, W; Miyake, K; Ota, I; Sakka, Y; Sugita, G; Yabe, N, 2008)
"Diclofenac-treated patients exhibited a marked fall in intraocular pressure (p<0."6.71The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. ( Antinozzi, PP; Caccavale, A; Costagliola, C; Cotticelli, L; Parmeggiani, F; Sebastiani, A, 2005)
"PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes."5.34Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020)
"To evaluate the comparative effects and safety of topical diclofenac sodium, fluorometholone, and dexamethasone for controlling inflammation after routine strabismus surgery."5.27A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery. ( Bae, S; Choi, DC; Choi, DG; Kim, J; Lee, JY, 2018)
"In this preliminary study, diclofenac sodium is at least as good as topical dexamethasone phosphate for glaucoma patients undergoing two-site combined phacotrabeculectomy with mitomycin C."5.17Postoperative treatment with topical diclofenac versus topical dexamethasone after combined phacotrabeculectomy with mitomycin C. ( Goldenfeld, M; Kalev-Landoi, M; Katz, G; Levkovitch-Verbin, H, 2013)
"Long-term prospective studies are needed to study the effect of topical treatment with latanoprost on the consequences of retinal hyperperfusion in retinal vascular diseases such as diabetic retinopathy."5.16Topical treatment for 1 week with latanoprost but not diclofenac reduces the diameter of dilated retinal arterioles in patients with type 1 diabetes mellitus and mild retinopathy. ( Bek, T; Tilma, KK, 2012)
"Intravitreal diclofenac is effective in the treatment of diffuse diabetic macular edema up to 12 weeks."5.15Intravitreal diclofenac versus intravitreal triamcinolone acetonide in the treatment of diabetic macular edema. ( Elbendary, AM; Shahin, MM, 2011)
"VA in both the diclofenac- and betamethasone-treated eyes significantly improved following the cataract surgery; however, no statistical difference of VA was noted between the diclofenac- and betamethasone-treated eyes throughout the observational period (before and after the surgery until 8 weeks postoperatively)."5.12Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes. ( Nakazawa, T; Nishida, K; Shimura, M; Yasuda, K, 2007)
"To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans."5.10Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003)
"Dexamethasone and diclofenac were equally effective in reducing postoperative inflammation after phacoemulsification and IOL implantation in eyes with no other disease than cataract."5.10Effects of dexamethasone, diclofenac, or placebo on the inflammatory response after cataract surgery. ( Laurell, CG; Zetterström, C, 2002)
"Latanoprost therapy enhances disruption of the blood-aqueous barrier and increases the incidence of angiographic CME formation in early postoperative pseudophakias."5.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."5.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)
" For prevention of postoperative intraocular pressure (IOP) elevation, carbachol 0."5.08[Minimally inflammatory cataract surgery]. ( Hessemer, V; Schartner, H; Schmidt, KG, 1996)
"In eyes with low to moderate myopia, the steroid and diclofenac subgroups had significantly different refractions 2 and 4 months postoperatively but no difference at 6 months; subjective haze grading was consistently lower in the steroid subgroup than in the NSAID subgroups (flurbiprofen, diclofenac) after 2 months."5.08Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy. ( Baek, SH; Chang, JH; Choi, SY; Lee, JH; Wee, WR, 1997)
"In the diclofenac group (n = 14), the preoperative intraocular pressure of 30."5.08The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. ( Cate, EA; Dubiner, HB; Kent, AR; Mundorf, TK; Stewart, JA; Stewart, WC; Whitaker, R, 1998)
"To evaluate effects of topical ophthalmic administration of diclofenac on intraocular pressure (IOP) when applied at 4 frequencies to eyes of Beagles."3.96Effect of topical administration of 0.1% diclofenac sodium ophthalmic solution at four frequencies on intraocular pressure in healthy Beagles. ( Colussi, JA; Henriksen, ML; Lappin, MR; Martabano, BB; Sharp, JL; Wang, Z, 2020)
"To evaluate the effect of a single dose of intravitreal diclofenac on macular edema (ME) due to branch retinal vein occlusion (BRVO)."3.83Intravitreal Diclofenac in the Treatment of Macular Edema Due to Branch Retinal Vein Occlusion. ( Arora, S; Ghosh, B; Gupta, A; Raina, UK; Seth, A, 2016)
"To compare the effects of topical diclofenac sodium with those of fluorometholone on intraocular pressure (IOP) and conjunctival inflammation after strabismus surgery."3.80Diclofenac versus fluorometholone after strabismus surgery in children. ( Han, SB; Hwang, JM; Yang, HK, 2014)
"Forty-two diabetic patients and 50 normal control patients who underwent small-incision phacoemulsification cataract surgery bilaterally received topical preservative-free diclofenac in 1 eye and preserved diclofenac in the other eye."3.78A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy. ( Miyazawa, A; Shimura, M; Yasuda, K, 2012)
" Topical administration of diclofenac and flurbiprofen should be used with caution in cats with a history of ocular hypertension."3.77Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats. ( Khrone, SG; Rankin, AJ; Stiles, J, 2011)
"To clarify the intraocular pressure (IOP)-lowering profile of tafluprost, a newly synthesised prostaglandin F(2alpha) analogue, in mice."3.74The IOP-lowering effects and mechanism of action of tafluprost in prostanoid receptor-deficient mice. ( Aihara, M; Araie, M; Narumiya, S; Ota, T; Saeki, T, 2007)
"This prospective non-comparative case series followed 77 eyes of 63 patients which showed signs of threatened early bleb failure and were treated with oral anti-inflammatory fibrosis suppression of prednisone, a non-steroidal anti-inflammatory agent, and colchicine taken for a mean period of 6 weeks, in addition to standard postoperative topical treatment, for a mean follow up of 6 years."3.71Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications. ( Bevin, TH; Fuller, JR; Herbison, P; Molteno, AC; Vote, BJ, 2002)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."3.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)
"005% latanoprost alone and in combination with 0."2.84Effect of topical ophthalmic latanoprost 0.005% solution alone and in combination with diclofenac 0.1% solution in healthy horses: a pilot study. ( Allbaugh, R; Ben-Shlomo, G; Griggs, A; Strong, T; Tofflemire, K; Whitley, EM; Whitley, RD, 2017)
"The intraocular pressures were measured at regular intervals during the 6-months follow-up period."2.80Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015)
"Diclofenac was more effective than betamethasone in preventing angiographic CME and BAB disruption after small-incision cataract surgery."2.73Reducing angiographic cystoid macular edema and blood-aqueous barrier disruption after small-incision phacoemulsification and foldable intraocular lens implantation: multicenter prospective randomized comparison of topical diclofenac 0.1% and betamethason ( Asano, S; Kimura, W; Miyake, K; Ota, I; Sakka, Y; Sugita, G; Yabe, N, 2008)
"Diclofenac-treated patients exhibited a marked fall in intraocular pressure (p<0."2.71The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. ( Antinozzi, PP; Caccavale, A; Costagliola, C; Cotticelli, L; Parmeggiani, F; Sebastiani, A, 2005)
" Side effect incidence and patient and investigator opinions were also recorded."2.69Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers. ( Andreu, D; Costa, J; Martínez, M; Notivol, R; Salvá, P, 1999)
"In the dosage used, diclofenac was as effective an anti-inflammatory agent for uncomplicated post-cataract inflammation as prednisolone."2.68A comparison of topical diclofenac with prednisolone for postcataract inflammation. ( Brennan, KM; Roberts, CW, 1995)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.92)18.7374
1990's17 (33.33)18.2507
2000's17 (33.33)29.6817
2010's12 (23.53)24.3611
2020's3 (5.88)2.80

Authors

AuthorsStudies
Weber, A1
Casini, A1
Heine, A1
Kuhn, D1
Supuran, CT1
Scozzafava, A1
Klebe, G1
Martabano, BB1
Henriksen, ML1
Colussi, JA1
Sharp, JL1
Wang, Z1
Lappin, MR1
Cagini, C1
Pellegrino, A1
Cerquaglia, A1
Iaccheri, B1
Lupidi, M1
Fiore, T1
Thrane, VR1
Thrane, AS1
Bergo, C1
Halvorsen, H1
Krohn, J1
Kim, J1
Choi, DC1
Bae, S1
Choi, DG1
Lee, JY1
Yang, HK1
Han, SB1
Hwang, JM1
Champagne, S1
Anctil, JL1
Goyette, A1
Lajoie, C1
Des Marchais, B1
Lee, TH1
Choi, W1
Ji, YS1
Yoon, KC1
Seth, A1
Ghosh, B1
Raina, UK1
Gupta, A1
Arora, S1
Tofflemire, K1
Whitley, EM1
Allbaugh, R1
Ben-Shlomo, G1
Griggs, A1
Strong, T1
Whitley, RD1
Maca, SM1
Amon, M1
Findl, O1
Kahraman, G1
Barisani-Asenbauer, T1
Rankin, AJ1
Khrone, SG1
Stiles, J1
Tilma, KK1
Bek, T1
Elbendary, AM1
Shahin, MM1
Levkovitch-Verbin, H1
Katz, G1
Kalev-Landoi, M1
Goldenfeld, M1
Yasuda, K2
Miyazawa, A1
Shimura, M2
Fuller, JR1
Bevin, TH1
Molteno, AC1
Vote, BJ1
Herbison, P1
Laurell, CG1
Zetterström, C1
Scuderi, B1
Driussi, GB1
Chizzolini, M1
Salvetat, ML1
Beltrame, G1
Stewart, WC3
Costagliola, C1
Parmeggiani, F1
Antinozzi, PP1
Caccavale, A1
Cotticelli, L1
Sebastiani, A1
Satav, SS1
Thomas, R1
Kahana, A1
Ota, T2
Aihara, M2
Saeki, T2
Narumiya, S2
Araie, M2
Akyol-Salman, I1
Leçe-Sertöz, D1
Baykal, O1
Nakazawa, T1
Nishida, K1
Asano, S1
Miyake, K3
Ota, I3
Sugita, G1
Kimura, W1
Sakka, Y1
Yabe, N1
Wheeldon, CE1
Hadden, OB1
Niederer, RL1
McGhee, CN1
Kim, SJ1
Adams, NA1
Toma, HS1
Belair, ML1
Thorne, JE1
Green, WR1
Jabs, DA1
Agata, M1
Abe, T1
Kon, M1
Tanaka, M1
Kimura, T1
Nakajima, A1
Roberts, CW1
Brennan, KM1
Constable, PH1
Adams, GG1
Gwin, TD1
Gwynn, DR1
Herbort, CP2
Mermoud, A2
Schnyder, C2
Pittet, N2
Diestelhorst, M2
Thull, D1
Krieglstein, GK1
Hessemer, V1
Schmidt, KG1
Schartner, H1
Ustundag, C1
Baek, SH1
Choi, SY1
Chang, JH1
Wee, WR1
Lee, JH1
Krohne, SG1
Gionfriddo, J1
Morrison, EA1
el-Harazi, SM1
Ruiz, RS1
Feldman, RM1
Villanueva, G1
Chuang, AZ1
Kent, AR1
Dubiner, HB1
Whitaker, R1
Mundorf, TK1
Stewart, JA1
Cate, EA1
Koçak, I1
Yalvaç, IS1
Koçak, A1
Nurözler, A1
Unlü, N1
Kasim, R1
Duman, S1
Maekubo, K2
Ichihashi, S2
Miyake, S2
Salvá, P1
Costa, J1
Andreu, D1
Notivol, R1
Martínez, M1
Snir, M1
Axer-Siegel, R1
Friling, R1
Weinberger, D1
Ibaraki, N1
Akura, J1
Shibuya, Y1
Strelow, SA1
Sherwood, MB1
Broncato, LJ1
Napier, A1
Driebe, WT1
Guy, JR1
Vickers, FF1
Mellars, K1
Castillo Laguarta, J1
Loras Alegre, E1
Minana Beamonte, I1
Ascaso Puyuelo, J1
Garcia Garcia, J1
Palomar Gomez, A1
Cristobal Bescos, JA1
Pillunat, LE1
Wagner, P1
Stodtmeister, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Control Study to Investigate if the Continuation of Prostaglandin Analogue Treatments in the Post-operative Phase of Glaucoma Patients Undergoing Cataract Surgery Increases the Incidence of Cystoid Macular Oedema.[NCT03292796]Phase 256 participants (Actual)Interventional2016-12-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

34 trials available for diclofenac and Intraocular Pressure

ArticleYear
Comparison of the Effect of Diclofenac 0.1% and Nepafenac 0.1% on Aqueous Flare in Patients Undergoing Cataract Surgery: A Prospective Randomized Study.
    Current eye research, 2020, Volume: 45, Issue:9

    Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueou

2020
Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty.
    Journal of glaucoma, 2020, Volume: 29, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dicl

2020
A Randomized Clinical Trial of Topical Diclofenac, Fluorometholone, and Dexamethasone for Control of Inflammation After Strabismus Surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2018, Volume: 34, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Child; Dexamethasone; Diclofenac; Female; Fluorometholon

2018
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit

2015
Effect of topical ophthalmic latanoprost 0.005% solution alone and in combination with diclofenac 0.1% solution in healthy horses: a pilot study.
    Veterinary ophthalmology, 2017, Volume: 20, Issue:5

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Diclofenac; Double-Blind Method; Drug The

2017
Efficacy and tolerability of preservative-free and preserved diclofenac and preserved ketorolac eyedrops after cataract surgery.
    American journal of ophthalmology, 2010, Volume: 149, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Diclofenac

2010
Topical treatment for 1 week with latanoprost but not diclofenac reduces the diameter of dilated retinal arterioles in patients with type 1 diabetes mellitus and mild retinopathy.
    Acta ophthalmologica, 2012, Volume: 90, Issue:8

    Topics: Administration, Topical; Adult; Antihypertensive Agents; Arterioles; Blood Glucose; Blood Pressure;

2012
Intravitreal diclofenac versus intravitreal triamcinolone acetonide in the treatment of diabetic macular edema.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diabetic Retinopathy; Diclofenac; Female; Glucocorti

2011
Postoperative treatment with topical diclofenac versus topical dexamethasone after combined phacotrabeculectomy with mitomycin C.
    Journal of glaucoma, 2013, Volume: 22, Issue:3

    Topics: Administration, Topical; Aged; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract;

2013
Effects of dexamethasone, diclofenac, or placebo on the inflammatory response after cataract surgery.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:12

    Topics: Aged; Aged, 80 and over; Cataract Extraction; Dexamethasone; Diclofenac; Double-Blind Method; Eye Di

2002
Effectiveness and tolerance of piroxicam 0.5% and diclofenac sodium 0.1% in controlling inflammation after cataract surgery.
    European journal of ophthalmology, 2003, Volume: 13, Issue:6

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofena

2003
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:11

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D

2003
The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients.
    Experimental eye research, 2005, Volume: 81, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Anti-Inflammatory

2005
Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Ch

2007
Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:3

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents

2007
Reducing angiographic cystoid macular edema and blood-aqueous barrier disruption after small-incision phacoemulsification and foldable intraocular lens implantation: multicenter prospective randomized comparison of topical diclofenac 0.1% and betamethason
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:1

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Blood-Aqueous

2008
A comparison of topical diclofenac with prednisolone for postcataract inflammation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:6

    Topics: Administration, Topical; Anterior Chamber; Cataract Extraction; Cell Count; Diclofenac; Double-Blind

1995
Use of topical diclofenac in association with external ocular compression.
    Eye (London, England), 1994, Volume: 8 ( Pt 4)

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Diclofenac; Humans; Intraocular Pressure; M

1994
Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:4

    Topics: Aged; Anterior Eye Segment; Diclofenac; Double-Blind Method; Drug Administration Schedule; Endophtha

1993
The effect of argon laser trabeculoplasty on the blood-aqueous barrier and intraocular pressure in human glaucomatous eyes treated with diclofenac 0.1%.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1995, Volume: 233, Issue:9

    Topics: Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Blood-Aqueous Barrier; Diclofenac; Female

1995
[Minimally inflammatory cataract surgery].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 209, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood-Aqueous Barrier; Carbachol; Dexamethasone; Dichlorphenamide; D

1996
Efficacy of argon laser trabeculoplasty: 3-year preliminary results of a prospective placebo-controlled study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1997, Volume: 235, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cyclooxygenase Inhibitors; Diclofenac; Disease Progression; Exfoliat

1997
Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; D

1997
A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C

1998
The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Chr

1998
Comparison of the anti-inflammatory effects of diclofenac and flurbiprofen eye drops after cataract extraction.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea; Diclofenac; Double-Blind

1998
Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:1

    Topics: Aged; Blood-Aqueous Barrier; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Fluoresce

1999
Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Conjunctiva; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinatio

1999
Efficacy of diclofenac versus dexamethasone for treatment after strabismus surgery.
    Ophthalmology, 2000, Volume: 107, Issue:10

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Prescho

2000
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory

2001
The effect of diclofenac sodium ophthalmic solution on intraocular pressure following cataract extraction.
    Ophthalmic surgery, 1992, Volume: 23, Issue:3

    Topics: Aged; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Follow-Up Studies; Humans; Incid

1992
[Anti-inflammatory effect of topical diclofenac sodium (Voltarène Ophta) after argon laser trabeculoplasty: preliminary results of a prospective double-blind method].
    Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5

    Topics: Aged; Anterior Chamber; Diclofenac; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Hum

1992
[Influence of topical administration of diclofenac on the reduction of intraocular pressure induced by timolol in healthy subjects].
    Journal francais d'ophtalmologie, 1991, Volume: 14, Issue:2

    Topics: Administration, Topical; Depression, Chemical; Diclofenac; Double-Blind Method; Drug Evaluation; Dru

1991
[Comparison of locally applied prostaglandin synthesis inhibitors in Nd:YAG laser surgery--initial results].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1987, Volume: 84, Issue:6

    Topics: Aged; Cataract Extraction; Clinical Trials as Topic; Diclofenac; Humans; Indomethacin; Intraocular P

1987

Other Studies

17 other studies available for diclofenac and Intraocular Pressure

ArticleYear
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
    Journal of medicinal chemistry, 2004, Jan-29, Volume: 47, Issue:3

    Topics: Animals; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Celecoxib; Crystallograp

2004
Effect of topical administration of 0.1% diclofenac sodium ophthalmic solution at four frequencies on intraocular pressure in healthy Beagles.
    American journal of veterinary research, 2020, Volume: 81, Issue:1

    Topics: Administration, Ophthalmic; Administration, Topical; Animals; Diclofenac; Dogs; Drug Administration

2020
Diclofenac versus fluorometholone after strabismus surgery in children.
    The British journal of ophthalmology, 2014, Volume: 98, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Conjuncti

2014
Comparison of ketorolac 0.45% versus diclofenac 0.1% for macular thickness and volume after uncomplicated cataract surgery.
    Acta ophthalmologica, 2016, Volume: 94, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Intrao

2016
Intravitreal Diclofenac in the Treatment of Macular Edema Due to Branch Retinal Vein Occlusion.
    Ophthalmic surgery, lasers & imaging retina, 2016, Volume: 47, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fluorescein Angiography; F

2016
Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.
    American journal of veterinary research, 2011, Volume: 72, Issue:6

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Aqueous Humor; Blood-Aqueous Barrier; Cat Disea

2011
A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Case-Control Studies; Cataract; Cataract Extracti

2012
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Dru

2002
Preventing steroid-induced glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glaucoma, Open-Angle; Glucocorticoids; Humans;

2005
Prevention of steroid-induced intraocular pressure elevation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytoskeletal Proteins; Diclofenac; Drug Delivery Systems; E

2005
The effects of prostaglandin analogues on prostanoid EP1, EP2, and EP3 receptor-deficient mice.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:8

    Topics: Animals; Antihypertensive Agents; Circadian Rhythm; Diclofenac; Intraocular Pressure; Mice; Mice, In

2006
The IOP-lowering effects and mechanism of action of tafluprost in prostanoid receptor-deficient mice.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:5

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Diclofenac; Intraocular Pressure; Mice; M

2007
Presumed late diffuse lamellar keratitis progressing to interface fluid syndrome.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:2

    Topics: Adult; Body Fluids; Corneal Stroma; Diclofenac; Drug Therapy, Combination; Humans; Intraocular Press

2008
Safety of intravitreal ketorolac and diclofenac: an electroretinographic and histopathologic study.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dark Adaptation; Diclofenac; Electroretinography;

2008
[Effect of topical diclofenac sodium, a non-steroidal anti-inflammatory drug, on various ocular inflammatory models in animals].
    Nippon Ganka Gakkai zasshi, 1983, Volume: 87, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclofenac; Eye Diseases;

1983
Filtration surgery in rabbits treated with diclofenac or prednisolone acetate.
    Ophthalmic surgery, 1994, Volume: 25, Issue:4

    Topics: Animals; Combined Modality Therapy; Diclofenac; Endophthalmitis; Glaucoma; Intraocular Pressure; Pre

1994
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
    American journal of veterinary research, 1998, Volume: 59, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclo

1998