diclofenac has been researched along with Hyperemia in 8 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Side effect incidence and patient and investigator opinions were also recorded." | 2.69 | Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers. ( Andreu, D; Costa, J; Martínez, M; Notivol, R; Salvá, P, 1999) |
| "Ibuprofen was the most efficient agent, inhibiting the total reactive hyperemia by more than 70%, and naproxen was least active, producing about 35% inhibition." | 2.65 | Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. ( Carlsson, I; Wennmalm, A, 1983) |
| "Bradykinin-induced increase in 6-ketoprostaglandin F1 alpha production was greater in coronary arteries taken from L-NNA-treated dogs (+ 179 +/- 41 pg/mm2) than from control dogs (+ 66 +/- 18 pg/mm2) (P < ." | 2.39 | Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs. Evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels. ( Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF; Puybasset, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kocak, I | 1 |
| Aydin, A | 1 |
| Sahbaz, I | 1 |
| Kaya, F | 1 |
| Baybora, H | 1 |
| Fromy, B | 1 |
| Lingueglia, E | 1 |
| Sigaudo-Roussel, D | 1 |
| Saumet, JL | 1 |
| Lazdunski, M | 1 |
| Carlsson, I | 1 |
| Wennmalm, A | 1 |
| Puybasset, L | 1 |
| Béa, ML | 1 |
| Ghaleh, B | 1 |
| Giudicelli, JF | 2 |
| Berdeaux, A | 2 |
| Andrieu, S | 1 |
| Lebret, M | 1 |
| Maclouf, J | 1 |
| Bévérelli, F | 1 |
| Salvá, P | 1 |
| Costa, J | 1 |
| Andreu, D | 1 |
| Notivol, R | 1 |
| Martínez, M | 1 |
| Hersh, PS | 1 |
| Rice, BA | 1 |
| Baer, JC | 1 |
| Wells, PA | 1 |
| Lynch, SE | 1 |
| McGuigan, LJ | 1 |
| Foster, CS | 1 |
| Phillis, JW | 1 |
| DeLong, RE | 1 |
| Towner, JK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Cutaneous Microcirculation: ASIC Involvement.[NCT01246180] | 20 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638] | Early Phase 1 | 80 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diclofenac and Hyperemia
| Article | Year |
|---|---|
Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs. Evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels.
Topics: Acetylcholine; Animals; Bradykinin; Coronary Circulation; Coronary Vessels; Diclofenac; Dogs; Epopro | 1996 |
2 trials available for diclofenac and Hyperemia
| Article | Year |
|---|---|
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemi | 1983 |
Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers.
Topics: Adolescent; Adult; Conjunctiva; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinatio | 1999 |
5 other studies available for diclofenac and Hyperemia
| Article | Year |
|---|---|
The management of corneal melt occurring after collagen cross-linking for keratoconus.
Topics: Adult; Conjunctival Diseases; Corneal Edema; Corneal Injuries; Cross-Linking Reagents; Dexamethasone | 2015 |
Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers.
Topics: Acid Sensing Ion Channels; Adult; Amiloride; Animals; Calcitonin; Cnidarian Venoms; Diclofenac; Endo | 2012 |
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cycl | 1999 |
Topical nonsteroidal agents and corneal wound healing.
Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Cornea; Corneal Edema; Corneal Inj | 1990 |
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diclofenac; Extracorporeal Circulation; Hypere | 1986 |