diclofenac has been researched along with Hepatic Encephalopathy in 3 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Already considered a drug that can reverse the toxic side effects of NSAIDs, BPC 157 (10 μg/kg, 10 ng/kg) was strongly effective throughout the entire experiment when given (i) intraperitoneally immediately after diclofenac or (ii) per-orally in drinking water (0." | 1.37 | Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions. ( Blagaic, AB; Brcic, L; Coric, M; Djakovic, Z; Djuzel, V; Drmic, D; Dzidic, S; Filipovic, M; Franjic, S; Gjurasin, M; Ilic, S; Klicek, R; Kolenc, D; Radic, B; Romic, Z; Seiwerth, S; Sever, M; Sikiric, P; Stambolija, V; Stupnisek, M; Zarkovic, K; Zoricic, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Alhaddad, O | 1 |
| Elsabaawy, M | 1 |
| Abdelsameea, E | 1 |
| Abdallah, A | 1 |
| Shabaan, A | 1 |
| Ehsan, N | 1 |
| Elrefaey, A | 1 |
| Elsabaawy, D | 1 |
| Salama, M | 1 |
| Ilic, S | 1 |
| Drmic, D | 1 |
| Franjic, S | 1 |
| Kolenc, D | 1 |
| Coric, M | 1 |
| Brcic, L | 1 |
| Klicek, R | 1 |
| Radic, B | 1 |
| Sever, M | 1 |
| Djuzel, V | 1 |
| Filipovic, M | 1 |
| Djakovic, Z | 1 |
| Stambolija, V | 1 |
| Blagaic, AB | 1 |
| Zoricic, I | 1 |
| Gjurasin, M | 1 |
| Stupnisek, M | 1 |
| Romic, Z | 1 |
| Zarkovic, K | 1 |
| Dzidic, S | 1 |
| Seiwerth, S | 1 |
| Sikiric, P | 1 |
| Jones, AL | 1 |
| Latham, T | 1 |
| Shallcross, TM | 1 |
| Simpson, KJ | 1 |
1 review available for diclofenac and Hepatic Encephalopathy
| Article | Year |
|---|---|
Fulminant hepatic failure due to diclofenac treated successfully by orthotopic liver transplantation.
Topics: Diclofenac; Female; Hepatic Encephalopathy; Humans; Liver Transplantation; Middle Aged | 1998 |
2 other studies available for diclofenac and Hepatic Encephalopathy
| Article | Year |
|---|---|
Presentations, Causes and Outcomes of Drug-Induced Liver Injury in Egypt.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amoxicillin-Potassium Clavulanate Combination; An | 2020 |
Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Behavior, | 2011 |