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diclofenac and Hemorrhage, Peptic Ulcer

diclofenac has been researched along with Hemorrhage, Peptic Ulcer in 15 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and gastrointestinal safety of nabumetone and diclofenac in the treatment of elderly patients with osteoarthritis, participating in a 3-month efficacy trial."5.09Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile. ( DeLapp, R; Kaine, J; Morgan , GJ; Palmer, R, 2001)
" However, clinical examination revealed that the patient had put a diclofenac hydroxyethylpyrrolidine plaster, which had been prescribed for lower back pain, inadvertently on a large ulcus cruris."3.70[Ulcer + ulcer]. ( Christ, AD; Speich, R; Stocker, DN, 1998)
"Cyclo-oxygenase (COX)-2 selective inhibitors (coxibs) were designed to reduce the incidence of gastrointestinal (GI) adverse events (AEs) which occur with non-selective NSAIDs (ns-NSAIDs)."2.44Global gastrointestinal safety profile of etoricoxib and lumiracoxib. ( Hunt, RH; Yuan, Y, 2007)
"A report is presented of five aged patients with hemorrhagic colon ulcer, which was strongly suspected to be a side effect of non steroidal anti-inflammatory drugs (NSAID)."1.30[Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients]. ( Kusakabe, N; Matsui, I; Matsui, Y; Matsumura, Y; Morimoto, S; Ogihara, T; Takahashi, E, 1997)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's9 (60.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Romero Vázquez, J1
Herrerías Gutiérrez, JM1
Caunedo-Alvarez, A1
Gómez-Rodríguez, BJ1
Romero-Vázquez, J1
Argüelles-Arias, F1
Romero-Castro, R1
García-Montes, JM1
Pellicer-Bautista, FJ1
Herrerías-Gutiérrez, JM1
Rahme, E1
Bernatsky, S1
Chan, FK1
Hung, LC1
Suen, BY1
Wu, JC1
Lee, KC1
Leung, VK1
Hui, AJ1
To, KF1
Leung, WK1
Wong, VW1
Chung, SC1
Sung, JJ1
Graham, DY1
Lanas, A1
Nurmohamed, MT1
Lems, WF1
Shostak, NA1
Riabkova, AA1
Savel'ev, VS1
Maliarova, LP1
Pilotto, A1
Seripa, D1
Franceschi, M1
Scarcelli, C1
Colaizzo, D1
Grandone, E1
Niro, V1
Andriulli, A1
Leandro, G1
Di Mario, F1
Dallapiccola, B1
Yuan, Y1
Hunt, RH1
Zimmerman, J1
Siguencia, J1
Tsvang, E1
Matsui, Y1
Matsui, I1
Kusakabe, N1
Matsumura, Y1
Takahashi, E1
Morimoto, S1
Ogihara, T1
Stocker, DN1
Christ, AD1
Speich, R1
Morgan , GJ1
Kaine, J1
DeLapp, R1
Palmer, R1
Novacek, G1
Geppert, A1
Kramer, L1
Wrba, F1
Herbst, F1
Schima, W1
Gangl, A1
Pötzi, R1

Reviews

2 reviews available for diclofenac and Hemorrhage, Peptic Ulcer

ArticleYear
Global gastrointestinal safety profile of etoricoxib and lumiracoxib.
    Current pharmaceutical design, 2007, Volume: 13, Issue:22

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Interactions;

2007
Liver penetration by a duodenal ulcer in a young woman.
    Journal of clinical gastroenterology, 2001, Volume: 33, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Diclofenac;

2001

Trials

2 trials available for diclofenac and Hemorrhage, Peptic Ulcer

ArticleYear
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis.
    The New England journal of medicine, 2002, Dec-26, Volume: 347, Issue:26

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Cyclooxygenase 2;

2002
Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile.
    Journal of clinical gastroenterology, 2001, Volume: 32, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Butanones; D

2001

Other Studies

11 other studies available for diclofenac and Hemorrhage, Peptic Ulcer

ArticleYear
Capsule endoscopy and nonsteroidal anti-inflammatory drugs (NSAID)-induced enteropathy--a bit of light in a long, dark tunel.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Clinical Trials as To

2010
Macroscopic small bowel mucosal injury caused by chronic nonsteroidal anti-inflammatory drugs (NSAID) use as assessed by capsule endoscopy.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Cyclooxygenase 2 Inhibitors

2010
NSAIDs and risk of lower gastrointestinal bleeding.
    Lancet (London, England), 2010, Jul-17, Volume: 376, Issue:9736

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Celecoxib; Coloni

2010
NSAIDs, Helicobacter pylori, and Pandora's Box.
    The New England journal of medicine, 2002, Dec-26, Volume: 347, Issue:26

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Cyclooxygenase 2;

2002
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding.
    The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase 2; Cyclooxygen

2003
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding.
    The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Contraindications; Cyclooxyge

2003
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:5

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodeno

2003
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
    Gastroenterology, 2007, Volume: 133, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cas

2007
Upper gastrointestinal hemorrhage associated with cutaneous application of diclofenac gel.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:11

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal;

1995
[Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1997, Volume: 34, Issue:9

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Diabetes Complications; Diclofenac;

1997
[Ulcer + ulcer].
    Therapeutische Umschau. Revue therapeutique, 1998, Volume: 55, Issue:9

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Back Pain

1998