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diclofenac and Hemolysis

diclofenac has been researched along with Hemolysis in 15 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"In the present study we examined the utility, sensitivity and specificity of the cadmium- and heat-induced hemolysis, investigating the effects of diclofenac, salicylate and lidocaine, carticaine and procaine on the rabbit erythrocyte membrane."7.66Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis. ( Weischer, CH, 1980)
"Diclofenac has been implicated in many cases of life-threatening immune hemolytic anemia (IHA)."5.33Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review. ( Ahrens, N; Genth, R; Kiesewetter, H; Salama, A, 2006)
" PP-g-(NIPAAm-r-APMA) films showed temperature-responsive swelling, smaller friction coefficients, hemolysis and thrombogenicity and higher cell compatibility, did not elicit secretion of cytokines, and took up remarkable amounts of diclofenac and ibuprofen and sustained delivery for several hours in phosphate buffer, pH 7."3.77Stimuli-responsive networks grafted onto polypropylene for the sustained delivery of NSAIDs. ( Alvarez-Lorenzo, C; Bucio, E; Concheiro, A; Contreras-García, A; Taboada, C, 2011)
" Eight NSAID (carprofen, diclofenac, ibuprofen, ketoprofen, naproxen, piroxicam, phenylbutazone, tiaprofenic acid) were assessed in a photohemolysis test for phototoxic effects in the visible light range."3.69Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light. ( Becker, L; Eberlein-König, B; Przybilla, B, 1996)
"In the present study we examined the utility, sensitivity and specificity of the cadmium- and heat-induced hemolysis, investigating the effects of diclofenac, salicylate and lidocaine, carticaine and procaine on the rabbit erythrocyte membrane."3.66Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis. ( Weischer, CH, 1980)
"Diclofenac has frequently been implicated as the cause of immune hemolytic anemias and less frequently of immune thrombocytopenia."2.42Diclofenac-induced antibodies against RBCs and platelets: two case reports and a concise review. ( Ahrens, N; Aslan, T; Hoffmann, T; Kiesewetter, H; Meyer, O; Salama, A, 2003)
"Aceclofenac (Airtal) (1) is a photoallergic and phototoxic anti-inflammatory and analgesic agent."1.34Photodegradation and in vitro phototoxicity of aceclofenac. ( Díaz, Y; Fuentes, A; Izzo, C; Padrón, L; Rivas, C; Vargas, F; Zoltan, T, 2007)
"Diclofenac has been implicated in many cases of life-threatening immune hemolytic anemia (IHA)."1.33Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review. ( Ahrens, N; Genth, R; Kiesewetter, H; Salama, A, 2006)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's3 (20.00)18.2507
2000's5 (33.33)29.6817
2010's4 (26.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
El Azab, EF1
Saleh, AM1
Yousif, SO1
Mazhari, BBZ1
Abu Alrub, H1
Elfaki, EM1
Hamza, A1
Abdulmalek, S1
Strimaite, M1
Harman, CLG1
Duan, H1
Wang, Y1
Davies, GL1
Williams, GR1
Zhao, L1
Liu, J1
Zhang, L1
Gao, Y1
Zhang, Z1
Luan, Y1
Bukara, K1
Drvenica, I1
Ilić, V1
Stančić, A1
Mišić, D1
Vasić, B1
Gajić, R1
Vučetić, D1
Kiekens, F1
Bugarski, B1
Contreras-García, A1
Alvarez-Lorenzo, C1
Taboada, C1
Concheiro, A1
Bucio, E1
Fuchs, T1
Puellmann, K1
Schneider, S1
Kruth, J1
Schulze, TJ1
Neumaier, M1
Beham, AW1
Kaminski, WE1
Meyer, O1
Hoffmann, T1
Aslan, T1
Ahrens, N2
Kiesewetter, H2
Salama, A2
Baydoun, L1
Müller-Goymann, CC1
Genth, R1
Tang, YZ1
Liu, ZQ1
Vargas, F1
Rivas, C1
Zoltan, T1
Fuentes, A1
Padrón, L1
Díaz, Y1
Izzo, C1
Weischer, CH1
Reer, O1
Bock, TK1
Müller, BW1
Iakovenko, IN1
Becker, L1
Eberlein-König, B1
Przybilla, B1

Reviews

1 review available for diclofenac and Hemolysis

ArticleYear
Diclofenac-induced antibodies against RBCs and platelets: two case reports and a concise review.
    Transfusion, 2003, Volume: 43, Issue:3

    Topics: Adult; Aged; Autoantibodies; Azepines; Blood Platelets; Coombs Test; Diclofenac; Erythrocytes; Femal

2003

Other Studies

14 other studies available for diclofenac and Hemolysis

ArticleYear
New insights into geraniol's antihemolytic, anti-inflammatory, antioxidant, and anticoagulant potentials using a combined biological and in silico screening strategy.
    Inflammopharmacology, 2022, Volume: 30, Issue:5

    Topics: Acyclic Monoterpenes; Animals; Anti-Inflammatory Agents; Anticoagulants; Antioxidants; Chlorides; Di

2022
Layered terbium hydroxides for simultaneous drug delivery and imaging.
    Dalton transactions (Cambridge, England : 2003), 2021, Jul-27, Volume: 50, Issue:29

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Survival; Diclofenac; Drug Deli

2021
Self-assembly properties, aggregation behavior and prospective application for sustained drug delivery of a drug-participating catanionic system.
    International journal of pharmaceutics, 2013, Aug-16, Volume: 452, Issue:1-2

    Topics: Animals; Cells, Cultured; Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Electric C

2013
Comparative studies on osmosis based encapsulation of sodium diclofenac in porcine and outdated human erythrocyte ghosts.
    Journal of biotechnology, 2016, Dec-20, Volume: 240

    Topics: Animals; Diclofenac; Drug Compounding; Drug Delivery Systems; Erythrocyte Membrane; Erythrocytes; He

2016
Stimuli-responsive networks grafted onto polypropylene for the sustained delivery of NSAIDs.
    Acta biomaterialia, 2011, Volume: 7, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Diclofenac; Hemolysis; Humans; Ibuprofe

2011
An autoimmune double attack.
    Lancet (London, England), 2012, Apr-07, Volume: 379, Issue:9823

    Topics: Acute Kidney Injury; Aged; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; A

2012
Influence of n-octenylsuccinate starch on in vitro permeation of sodium diclofenac across excised porcine cornea in comparison to Voltaren ophtha.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2003, Volume: 56, Issue:1

    Topics: Adjuvants, Pharmaceutic; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2003
Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review.
    American journal of hematology, 2006, Volume: 81, Issue:2

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antibodies; Coombs Test

2006
Evaluation of the free-radical-scavenging activity of diclofenac acid on the free-radical-induced haemolysis of human erythrocytes.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:5

    Topics: Amidines; Ascorbic Acid; Chromans; Diclofenac; Dose-Response Relationship, Drug; Drug Combinations;

2006
Photodegradation and in vitro phototoxicity of aceclofenac.
    Die Pharmazie, 2007, Volume: 62, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Dermatitis, Phototoxic; Diclofenac; Erythrocytes;

2007
Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:11

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Cadmium; Carticaine; Diclofenac; Dose-Respons

1980
In vitro corneal permeability of diclofenac sodium in formulations containing cyclodextrins compared to the commercial product voltaren ophtha.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:9

    Topics: Animals; Chromatography, High Pressure Liquid; Cornea; Cyclodextrins; Diclofenac; Hemolysis; Humans;

1994
[The effect of nonsteroidal anti-inflammatory agents on erythrocyte osmotic resistance].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Hemo

1993
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocyte

1996