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diclofenac and Granuloma

diclofenac has been researched along with Granuloma in 22 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Research Excerpts

ExcerptRelevanceReference
"This study demonstrates targeted delivery of diclofenac to an inflammatory environment using the granuloma air pouch model and diclofenac nanoemulsions with different compositions."7.78Albumin coupled lipid nanoemulsions of diclofenac for targeted delivery to inflammation. ( Goparaboina, S; Kandadi, P; Syed, MA; Veerabrahma, K, 2012)
"Diclofenac could be used successfully as a preventive agent against schistosomiasis mansoni infection in endemic areas."7.74Prophylactic effect of the anti-inflammatory drug diclofenac in experimental schistosomiasis mansoni. ( Mahmoud, S; Nessim, NG, 2007)
"Angiostasis and vascular regression in chronic granulomatous inflammation was assessed in mice induced with diclofenac in combination with hyaluronan."7.69Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice. ( Alam, CA; Seed, MP; Willoughby, DA, 1995)
"We report a case of severe colitis from diclofenac (Voltaren), one of a number of nonsteroidal anti-inflammatory drugs (NSAIDs) that can cause colonic injury."7.69A case of diclofenac-induced colitis with focal granulomatous change. ( Baert, F; Blackstone, MO; Hart, J, 1995)
" Compounds that showed promising COX-2 selectivity were further subjected to in vivo anti-inflammatory screening applying formalin induced paw edema (acute model) and cotton-pellet induced granuloma (chronic model) assays using celecoxib and diclofenac sodium as reference drugs."3.88Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidine derivatives bearing thiazolidinone moiety as anti-inflammatory agents. ( Ashour, HM; Fahmy, SM; Khalil, MA; Labouta, IM; Nassra, RA; Tageldin, GN, 2018)
"Anti-inflammatory activity of SiE was investigated in rats using ethyl phenylpropiolate (EPP)-induced ear edema, carrageenan- and arachidonic acid (AA)-induced hind paw edema, and cotton pellet-induced granuloma formation models."3.81Investigation of anti-inflammatory, antinociceptive and antipyretic activities of Stahlianthus involucratus rhizome ethanol extract. ( Chiranthanut, N; Khonsung, P; Kunanusorn, P; Panthong, A; Pingsusaen, P; Rujjanawate, C, 2015)
"This study demonstrates targeted delivery of diclofenac to an inflammatory environment using the granuloma air pouch model and diclofenac nanoemulsions with different compositions."3.78Albumin coupled lipid nanoemulsions of diclofenac for targeted delivery to inflammation. ( Goparaboina, S; Kandadi, P; Syed, MA; Veerabrahma, K, 2012)
"Diclofenac could be used successfully as a preventive agent against schistosomiasis mansoni infection in endemic areas."3.74Prophylactic effect of the anti-inflammatory drug diclofenac in experimental schistosomiasis mansoni. ( Mahmoud, S; Nessim, NG, 2007)
"Diclofenac had no significant effect on GAG or hydroxyproline content of implanted cartilage or on granuloma cytokine concentrations."3.70Effects of diacerhein on granuloma induced cartilage breakdown in the mouse. ( Alam, CA; Greenslade, KJ; Moore, AR; Willoughby, DA, 1998)
"Angiostasis and vascular regression in chronic granulomatous inflammation was assessed in mice induced with diclofenac in combination with hyaluronan."3.69Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice. ( Alam, CA; Seed, MP; Willoughby, DA, 1995)
"We report a case of severe colitis from diclofenac (Voltaren), one of a number of nonsteroidal anti-inflammatory drugs (NSAIDs) that can cause colonic injury."3.69A case of diclofenac-induced colitis with focal granulomatous change. ( Baert, F; Blackstone, MO; Hart, J, 1995)
"Diclofenac sodium was used as a standard drug."1.32Effect of alcohol extract of Achyranthes aspera Linn. on acute and subacute inflammation. ( Jegadeesan, M; Vetrichelvan, T, 2003)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's5 (22.73)18.2507
2000's7 (31.82)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Nwaehujor, C1
Selvaraj, S1
Oh, JH1
Borlak, J1
Tageldin, GN2
Fahmy, SM2
Ashour, HM2
Khalil, MA2
Nassra, RA2
Labouta, IM2
Ibrahim, TM1
Pingsusaen, P1
Kunanusorn, P1
Khonsung, P1
Chiranthanut, N1
Panthong, A1
Rujjanawate, C1
Su, YJ1
Lai, YC1
Lende, AB1
Kshirsagar, AD1
Deshpande, AD1
Muley, MM1
Patil, RR1
Bafna, PA1
Naik, SR1
Chouhan, CS1
Sridevi, K1
Singh, NK1
Singh, SK1
Kandadi, P1
Syed, MA1
Goparaboina, S1
Veerabrahma, K1
Meléndez Camargo, ME1
Buendía Romero, M1
Ramos Zamora, D1
Cardona Carrillo, P1
Villarreal Maldonado, ME1
Vetrichelvan, T1
Jegadeesan, M1
Groppo, FC1
Simões, RP1
Ramacciato, JC1
Rehder, V1
de Andrade, ED1
Mattos-Filho, TR1
Altaykan, A1
Erkin, G1
Boztepe, G1
Gököz, A1
Santos, LH1
Feres, CA1
Melo, FH1
Coelho, MM1
Nothenberg, MS1
Oga, S1
Tagliati, CA1
Nessim, NG1
Mahmoud, S1
Alam, CA3
Seed, MP2
Willoughby, DA3
Baert, F1
Hart, J1
Blackstone, MO1
Freemantle, C1
Brown, JR1
Moore, AR1
Greenslade, KJ1
Kanda, K1
Kume, K1
Yoshikawa, I1
Kai, R1
Nagata, K1
Tamura, M1
Yamasaki, T1
Otsuki, M1
Grau, M1
Guasch, J1
Montero, JL1
Felipe, A1
Carrasco, E1
Juliá, S1
de Menezes, MR1
Catanzaro-Guimarães, SA1

Reviews

1 review available for diclofenac and Granuloma

ArticleYear
The modulation of granulomatous tissue and tumour angiogenesis by diclofenac in combination with hyaluronan (HYAL EX-0001).
    International journal of tissue reactions, 1995, Volume: 17, Issue:4

    Topics: Animals; Diclofenac; Drug Delivery Systems; Granuloma; Humans; Hyaluronic Acid; Neoplasms; Neovascul

1995

Other Studies

21 other studies available for diclofenac and Granuloma

ArticleYear
Ficus vogelii methanol leaf extract ameliorates inflammation and arthritis by modulating osmotic fragility in C57BL/6J mice.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2021, Dec-31, Volume: 36, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Diclofenac; Edema; Ficus; G

2021
An adverse outcome pathway for immune-mediated and allergic hepatitis: a case study with the NSAID diclofenac.
    Archives of toxicology, 2020, Volume: 94, Issue:8

    Topics: Adipokines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury

2020
Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidine derivatives bearing thiazolidinone moiety as anti-inflammatory agents.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: Animals; Anti-Inflammatory Agents; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 I

2018
Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents.
    Bioorganic chemistry, 2019, Volume: 90

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhi

2019
Investigation of anti-inflammatory, antinociceptive and antipyretic activities of Stahlianthus involucratus rhizome ethanol extract.
    Journal of ethnopharmacology, 2015, Mar-13, Volume: 162

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Arachidonic Acid; Carragee

2015
Gluteal injection site granuloma.
    The Journal of emergency medicine, 2012, Volume: 43, Issue:1

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Buttocks; Diclofenac; Female; Granuloma;

2012
Anti-inflammatory and analgesic activity of protocatechuic acid in rats and mice.
    Inflammopharmacology, 2011, Volume: 19, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

2011
Anti-inflammatory activity of ethanol extract of Vitex glabrata leaves.
    Pakistan journal of pharmaceutical sciences, 2012, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Disease Models, Animal; E

2012
Albumin coupled lipid nanoemulsions of diclofenac for targeted delivery to inflammation.
    Nanomedicine : nanotechnology, biology, and medicine, 2012, Volume: 8, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Diclofenac; Drug Delivery Systems; Emulsio

2012
Study of the anti-inflammatory effect of Sedum praealtum (Siempreviva) in the rat: dose-dependent response.
    Proceedings of the Western Pharmacology Society, 2002, Volume: 45

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Diclofenac; Dose-Response Relationship

2002
Effect of alcohol extract of Achyranthes aspera Linn. on acute and subacute inflammation.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:1

    Topics: Achyranthes; Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Dose-Response Relationship,

2003
Effect of sodium diclofenac on serum and tissue concentration of amoxicillin and on staphylococcal infection.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:1

    Topics: Amoxicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Interactions; Granul

2004
Interstitial granulomatous dermatitis with arthritis.
    Human pathology, 2004, Volume: 35, Issue:7

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biopsy; Clemastine; Der

2004
Anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2004, Volume: 37, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Drug Combinations; Drug Eval

2004
Prophylactic effect of the anti-inflammatory drug diclofenac in experimental schistosomiasis mansoni.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2007, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Granuloma; Liver Diseases, Parasitic;

2007
Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:5

    Topics: Administration, Topical; Animals; Blood Vessels; Chronic Disease; Diclofenac; Drug Combinations; Fem

1995
A case of diclofenac-induced colitis with focal granulomatous change.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:10

    Topics: Aged; Colitis; Crohn Disease; Diagnosis, Differential; Diclofenac; Female; Granuloma; Humans

1995
Effects of diacerhein on granuloma induced cartilage breakdown in the mouse.
    Osteoarthritis and cartilage, 1998, Volume: 6, Issue:1

    Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; D

1998
[A case of non-steroidal anti-inflammatory drug-induced colitis with granulomas].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2002, Volume: 99, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Diclofenac; Female; Granu

2002
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary

1991
Determination of anti-inflammatory and antimitotic activities of non-steroid anti-inflammatory drugs ibuprofen, diclofenac sodium and fentiazac.
    Cellular and molecular biology, 1985, Volume: 31, Issue:6

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Division; Diclofenac; Fema

1985