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diclofenac and Glaucoma, Suspect

diclofenac has been researched along with Glaucoma, Suspect in 7 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Research Excerpts

ExcerptRelevanceReference
"PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes."9.34Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020)
" Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application."9.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."9.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)
"PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes."5.34Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020)
"To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans."5.10Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003)
" Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application."5.09Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999)
" The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol."5.09Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001)
" Topical administration of diclofenac and flurbiprofen should be used with caution in cats with a history of ocular hypertension."3.77Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats. ( Khrone, SG; Rankin, AJ; Stiles, J, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Thrane, VR1
Thrane, AS1
Bergo, C1
Halvorsen, H1
Krohn, J1
Jayson, S1
Sanchez-Migallon Guzman, D1
Petritz, O1
Freeman, K1
Maggs, DJ1
Rankin, AJ1
Khrone, SG1
Stiles, J1
Stewart, WC1
Miyake, K2
Ota, I2
Maekubo, K2
Ichihashi, S2
Miyake, S2
Ibaraki, N1
Akura, J1
Shibuya, Y1
Strelow, SA1
Sherwood, MB1
Broncato, LJ1
Napier, A1
Driebe, WT1
Guy, JR1
Vickers, FF1
Mellars, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Control Study to Investigate if the Continuation of Prostaglandin Analogue Treatments in the Post-operative Phase of Glaucoma Patients Undergoing Cataract Surgery Increases the Incidence of Cystoid Macular Oedema.[NCT03292796]Phase 256 participants (Actual)Interventional2016-12-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for diclofenac and Glaucoma, Suspect

ArticleYear
Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty.
    Journal of glaucoma, 2020, Volume: 29, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dicl

2020
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:11

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D

2003
Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:1

    Topics: Aged; Blood-Aqueous Barrier; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Fluoresce

1999
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory

2001
The effect of diclofenac sodium ophthalmic solution on intraocular pressure following cataract extraction.
    Ophthalmic surgery, 1992, Volume: 23, Issue:3

    Topics: Aged; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Follow-Up Studies; Humans; Incid

1992

Other Studies

2 other studies available for diclofenac and Glaucoma, Suspect

ArticleYear
Medical management of acute ocular hypertension in a western screech owl (Megascops kennicottii).
    Journal of avian medicine and surgery, 2014, Volume: 28, Issue:1

    Topics: Acute Disease; Animals; Bird Diseases; Carbonic Anhydrase Inhibitors; Diclofenac; Mannitol; Meloxica

2014
Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.
    American journal of veterinary research, 2011, Volume: 72, Issue:6

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Aqueous Humor; Blood-Aqueous Barrier; Cat Disea

2011