diclofenac has been researched along with Chronic Primary Open Angle Glaucoma in 14 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes." | 9.34 | Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020) |
| " Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application." | 9.09 | Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999) |
| " The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol." | 9.09 | Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001) |
| "Diclofenac-treated patients exhibited a marked fall in intraocular pressure (p<0." | 6.71 | The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. ( Antinozzi, PP; Caccavale, A; Costagliola, C; Cotticelli, L; Parmeggiani, F; Sebastiani, A, 2005) |
| "PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes." | 5.34 | Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020) |
| "To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans." | 5.10 | Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003) |
| " Because administration of nonsteroidal eyedrops such as diclofenac seems to prevent the adverse effects of latanoprost therapy while maintaining its effect to lower intraocular pressure, we suggest their concurrent application." | 5.09 | Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias. ( Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I, 1999) |
| " The concurrent administration of nonsteroidal anti-inflammatory drug such as diclofenac prevents these adverse effects without interfering with the drop in intraocular pressure caused by timolol." | 5.09 | Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. ( Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y, 2001) |
| "In the diclofenac group (n = 14), the preoperative intraocular pressure of 30." | 5.08 | The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. ( Cate, EA; Dubiner, HB; Kent, AR; Mundorf, TK; Stewart, JA; Stewart, WC; Whitaker, R, 1998) |
| "This prospective non-comparative case series followed 77 eyes of 63 patients which showed signs of threatened early bleb failure and were treated with oral anti-inflammatory fibrosis suppression of prednisone, a non-steroidal anti-inflammatory agent, and colchicine taken for a mean period of 6 weeks, in addition to standard postoperative topical treatment, for a mean follow up of 6 years." | 3.71 | Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications. ( Bevin, TH; Fuller, JR; Herbison, P; Molteno, AC; Vote, BJ, 2002) |
| "The intraocular pressures were measured at regular intervals during the 6-months follow-up period." | 2.80 | Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015) |
| "Diclofenac-treated patients exhibited a marked fall in intraocular pressure (p<0." | 2.71 | The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. ( Antinozzi, PP; Caccavale, A; Costagliola, C; Cotticelli, L; Parmeggiani, F; Sebastiani, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Thrane, VR | 1 |
| Thrane, AS | 1 |
| Bergo, C | 1 |
| Halvorsen, H | 1 |
| Krohn, J | 1 |
| Champagne, S | 1 |
| Anctil, JL | 1 |
| Goyette, A | 1 |
| Lajoie, C | 1 |
| Des Marchais, B | 1 |
| Fuller, JR | 1 |
| Bevin, TH | 1 |
| Molteno, AC | 1 |
| Vote, BJ | 1 |
| Herbison, P | 1 |
| Stewart, WC | 2 |
| Costagliola, C | 1 |
| Parmeggiani, F | 1 |
| Antinozzi, PP | 1 |
| Caccavale, A | 1 |
| Cotticelli, L | 1 |
| Sebastiani, A | 1 |
| Satav, SS | 1 |
| Thomas, R | 1 |
| Kahana, A | 1 |
| Rath, EZ | 1 |
| Rumelt, S | 1 |
| Herbort, CP | 2 |
| Mermoud, A | 2 |
| Schnyder, C | 2 |
| Pittet, N | 2 |
| Ustundag, C | 1 |
| Diestelhorst, M | 1 |
| Kent, AR | 1 |
| Dubiner, HB | 1 |
| Whitaker, R | 1 |
| Mundorf, TK | 1 |
| Stewart, JA | 1 |
| Cate, EA | 1 |
| Miyake, K | 2 |
| Ota, I | 2 |
| Maekubo, K | 2 |
| Ichihashi, S | 2 |
| Miyake, S | 2 |
| Ibaraki, N | 1 |
| Akura, J | 1 |
| Shibuya, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Control Study to Investigate if the Continuation of Prostaglandin Analogue Treatments in the Post-operative Phase of Glaucoma Patients Undergoing Cataract Surgery Increases the Incidence of Cystoid Macular Oedema.[NCT03292796] | Phase 2 | 56 participants (Actual) | Interventional | 2016-12-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for diclofenac and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dicl | 2020 |
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit | 2015 |
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D | 2003 |
The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Anti-Inflammatory | 2005 |
Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty.
Topics: Aged; Anterior Eye Segment; Diclofenac; Double-Blind Method; Drug Administration Schedule; Endophtha | 1993 |
Efficacy of argon laser trabeculoplasty: 3-year preliminary results of a prospective placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Cyclooxygenase Inhibitors; Diclofenac; Disease Progression; Exfoliat | 1997 |
The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Chr | 1998 |
Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias.
Topics: Aged; Blood-Aqueous Barrier; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Fluoresce | 1999 |
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory | 2001 |
[Anti-inflammatory effect of topical diclofenac sodium (Voltarène Ophta) after argon laser trabeculoplasty: preliminary results of a prospective double-blind method].
Topics: Aged; Anterior Chamber; Diclofenac; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Hum | 1992 |
4 other studies available for diclofenac and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Dru | 2002 |
Preventing steroid-induced glaucoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glaucoma, Open-Angle; Glucocorticoids; Humans; | 2005 |
Prevention of steroid-induced intraocular pressure elevation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytoskeletal Proteins; Diclofenac; Drug Delivery Systems; E | 2005 |
Acute visual loss due to serous retinal detachment from acquired optic pit may be a rare presentation of primary open-angle glaucoma.
Topics: Acute Disease; Antihypertensive Agents; Diclofenac; Drug Therapy, Combination; Female; Fluorescein A | 2007 |