Page last updated: 2024-10-26

diclofenac and Gastritis

diclofenac has been researched along with Gastritis in 10 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.

Research Excerpts

ExcerptRelevanceReference
"This patient, who had a history of osteoarthritis, had severe hepatitis 5 weeks after being started on diclofenac for increasing pain in the joints."3.70Diclofenac-associated hepatitis. ( Al-Baghdadi, Y; Bhogaraju, A; Nazeer, S; Patel, N; Rahman, M; Wrestler, F, 1999)
"Chronic gastritis was seen in 76% of the patients taking NSAID and in 58% of the control cases; active inflammation was detected in 10% of the NSAID treated patients and in 24% of the control cases, and it appeared closely related with Helicobacter pylori infection."1.29Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs. ( Aleotti, A; Alvisi, V; Caselli, M; DeCarlo, L; LaCorte, R; Ruina, M; Trevisani, L; Trotta, F, 1995)
" Duodenal mucosal injury, with or without gastric lesions, related to long-term use of anti-inflammatory drugs such as aspirin, indomethacin, ibuprofen, diclofenac or others are reported in three patients, in which the diagnosis was confirmed by emergency endoscopy after hematemesis."1.26Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs. ( Ikeda, S; Tanaka, M; Uchiyama, M, 1977)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mazumder, S1
De, R1
Sarkar, S1
Siddiqui, AA1
Saha, SJ1
Banerjee, C1
Iqbal, MS1
Nag, S1
Debsharma, S1
Bandyopadhyay, U1
Caselli, M1
LaCorte, R1
DeCarlo, L1
Aleotti, A1
Trevisani, L1
Ruina, M1
Trotta, F1
Alvisi, V1
Bhogaraju, A1
Nazeer, S1
Al-Baghdadi, Y1
Rahman, M1
Wrestler, F1
Patel, N1
Sasahara, K1
Uchida, Y1
Matsuda, K1
Kawabata, H1
Nishioka, M1
Mazzone, M1
Siciliano, M1
Carella, G1
Matsui, H1
Murata, Y1
Kobayashi, F1
Shiba, R1
Momo, K1
Kondo, Y1
Nakahara, A1
Muto, H1
Pemberton, RE1
Strand, LJ1
Osnes, M1
Larsen, S1
Eidsaunet, W1
Thom, E1
Tanaka, M1
Uchiyama, M1
Ikeda, S1
O'brien, WM1

Trials

2 trials available for diclofenac and Gastritis

ArticleYear
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as

1979
Effect of diclofenac and naproxen on gastroduodenal mucosa.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

    Topics: Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Duodenum; Female; Gastric Mucosa;

1979

Other Studies

8 other studies available for diclofenac and Gastritis

ArticleYear
Selective scavenging of intra-mitochondrial superoxide corrects diclofenac-induced mitochondrial dysfunction and gastric injury: A novel gastroprotective mechanism independent of gastric acid suppression.
    Biochemical pharmacology, 2016, Dec-01, Volume: 121

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Chemotaxis, Leukocyte; Diclo

2016
Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs.
    Journal of clinical pathology, 1995, Volume: 48, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Female; Gastric M

1995
Diclofenac-associated hepatitis.
    Southern medical journal, 1999, Volume: 92, Issue:7

    Topics: Alanine Transaminase; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Amino

1999
Role of energy metabolism in drug-induced acute gastric mucosal injuries in humans.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents; An

2000
Multiple diclofenac-induced adverse effects.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Aged; Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Gastritis;

2000
Diclofenac-induced gastric mucosal fluorescence in rats.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalase; Chromatography, High

2001
Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.
    Endoscopy, 1977, Volume: 9, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Aspirin; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Fiber Optic

1977
Adverse reactions to nonsteroidal anti-inflammatory drugs. Diclofenac compared with other nonsteroidal anti-inflammatory drugs.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Aged; Anaphylaxis; Anemia, Aplastic; Anti-Inflammatory Agents; Asthma; Blood Platelets; Chemical and

1986