diclofenac has been researched along with Fibrosis in 8 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The distribution of epidural fibrosis density, percentage of fibrosis, and distribution of fibroblasts in the diclofenac sodium + diltiazem group were significantly lower than in the other groups." | 7.91 | Preventative effect of diclofenac sodium and/or diltiazem in rats with epidural fibrosis. ( Akar, EA; Aker, FV; Emon, ST; Engin, T; Erdogan, B; Is, M; Sayman, E; Somay, H, 2019) |
| " It was found that a clinically useful degree of suppression of bleb inflammation and fibrosis can be obtained with a 4-6 week course of the combined systemic administration of prednisone (10 mg t." | 4.82 | Systemic anti-inflammatory fibrosis suppression in threatened trabeculectomy failure. ( Bevin, TH; Fuller, JR; Molteno, AC; Vote, B, 2004) |
| "The distribution of epidural fibrosis density, percentage of fibrosis, and distribution of fibroblasts in the diclofenac sodium + diltiazem group were significantly lower than in the other groups." | 3.91 | Preventative effect of diclofenac sodium and/or diltiazem in rats with epidural fibrosis. ( Akar, EA; Aker, FV; Emon, ST; Engin, T; Erdogan, B; Is, M; Sayman, E; Somay, H, 2019) |
| "This prospective non-comparative case series followed 77 eyes of 63 patients which showed signs of threatened early bleb failure and were treated with oral anti-inflammatory fibrosis suppression of prednisone, a non-steroidal anti-inflammatory agent, and colchicine taken for a mean period of 6 weeks, in addition to standard postoperative topical treatment, for a mean follow up of 6 years." | 3.71 | Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications. ( Bevin, TH; Fuller, JR; Herbison, P; Molteno, AC; Vote, BJ, 2002) |
| "Peridural fibrosis is one of the more frequent complications of lumbar surgery." | 1.35 | Preventing peridural fibrosis with nonsteroidal anti-inflammatory drugs. ( Hernandez-Vaquero, D; Sandoval, MA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, HB | 1 |
| Hong, JY | 1 |
| Kim, CR | 1 |
| Min, CH | 1 |
| Han, JH | 1 |
| Kim, MJ | 1 |
| Kim, SN | 1 |
| Lee, C | 1 |
| Choy, YB | 1 |
| Erdogan, B | 1 |
| Is, M | 1 |
| Aker, FV | 1 |
| Emon, ST | 1 |
| Engin, T | 1 |
| Akar, EA | 1 |
| Sayman, E | 1 |
| Somay, H | 1 |
| Vuralkan, E | 1 |
| Cobanoglu, HB | 1 |
| Arslan, A | 1 |
| Arslan, S | 1 |
| Mungan, S | 1 |
| Tatar, S | 1 |
| Toklu, AS | 1 |
| Fuller, JR | 2 |
| Bevin, TH | 3 |
| Molteno, AC | 3 |
| Vote, BJ | 1 |
| Herbison, P | 1 |
| Vote, B | 1 |
| Ors Kaya, S | 1 |
| Bir, F | 1 |
| Atalay, H | 1 |
| Onem, G | 1 |
| Aytekin, FO | 1 |
| Saçar, M | 1 |
| Ah-Chan, JJ | 1 |
| Sandoval, MA | 1 |
| Hernandez-Vaquero, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analysis of Effect of Low Level Laser Therapy in Spinal Surgery[NCT02529657] | 48 participants (Actual) | Interventional | 2013-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diclofenac and Fibrosis
| Article | Year |
|---|---|
Systemic anti-inflammatory fibrosis suppression in threatened trabeculectomy failure.
Topics: Anti-Inflammatory Agents; Atropine; Blister; Colchicine; Conjunctiva; Diclofenac; Drug Therapy, Comb | 2004 |
7 other studies available for diclofenac and Fibrosis
| Article | Year |
|---|---|
Microchannel-embedded implantable device with fibrosis suppression for prolonged controlled drug delivery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Chemistry, Pharmaceutical; Delayed- | 2022 |
Preventative effect of diclofenac sodium and/or diltiazem in rats with epidural fibrosis.
Topics: Animals; Diclofenac; Diltiazem; Epidural Space; Fibrosis; Laminectomy; Rats | 2019 |
Effects of topical nasal steroids and diclofenac on the nasal mucosa during hyperbaric oxygen therapy: a double-blind experimental study.
Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Dru | 2002 |
Effect of diclofenac on experimental pleurodesis induced by tetracycline in rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Fibrosis; Male | 2005 |
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure.
Topics: Aged; Anti-Inflammatory Agents; Chronic Disease; Colchicine; Conjunctiva; Conjunctival Diseases; Dic | 2006 |
Preventing peridural fibrosis with nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cicatrix; Connective Tissue; Diclofenac; Disease M | 2008 |