diclofenac has been researched along with Fibrosarcoma in 6 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Positive effects of repeated administration of diclofenac, an inhibitor of prostaglandin synthesis, in terms of prevention of tumor development and stimulation of hematopoiesis have been observed in C3H mice transplanted subcutaneously with G:5:113 fibrosarcoma cells." | 7.71 | Hematopoiesis-stimulating and anti-tumor effects of repeated administration of diclofenac in mice with transplanted fibrosarcoma cells. ( Fedorocko, P; Hofer, M; Hoferová, Z; Macková, NO, 2002) |
| "For suppression of primary G:5:113 fibrosarcoma growth, three structurally different cyclooxygenase (COX) inhibitors (ibuprofen, flurbiprofen, and diclofenac) were administered intraperitoneally (i." | 7.71 | The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma. ( Egyed, A; Fedorocko, P; Hofer, M; Hoferová, Z; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Znojil, V, 2002) |
| "Positive effects of repeated administration of diclofenac, an inhibitor of prostaglandin synthesis, in terms of prevention of tumor development and stimulation of hematopoiesis have been observed in C3H mice transplanted subcutaneously with G:5:113 fibrosarcoma cells." | 3.71 | Hematopoiesis-stimulating and anti-tumor effects of repeated administration of diclofenac in mice with transplanted fibrosarcoma cells. ( Fedorocko, P; Hofer, M; Hoferová, Z; Macková, NO, 2002) |
| "For suppression of primary G:5:113 fibrosarcoma growth, three structurally different cyclooxygenase (COX) inhibitors (ibuprofen, flurbiprofen, and diclofenac) were administered intraperitoneally (i." | 3.71 | The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma. ( Egyed, A; Fedorocko, P; Hofer, M; Hoferová, Z; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Znojil, V, 2002) |
| "The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth." | 3.66 | Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. ( Peterson, HI, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hofer, M | 3 |
| Hoferová, Z | 3 |
| Fedorocko, P | 3 |
| Macková, NO | 1 |
| Brezáni, P | 1 |
| Saadat, F | 2 |
| Zomorodian, K | 1 |
| Pezeshki, M | 1 |
| Rezaie, S | 1 |
| Khorramizadeh, MR | 2 |
| Mirshafiey, A | 1 |
| Peterson, HI | 1 |
| Hofmanová, J | 1 |
| Znojil, V | 1 |
| Minksová, K | 1 |
| Soucek, K | 1 |
| Egyed, A | 1 |
| Kozubík, A | 1 |
6 other studies available for diclofenac and Fibrosarcoma
| Article | Year |
|---|---|
Hematopoiesis-stimulating and anti-tumor effects of repeated administration of diclofenac in mice with transplanted fibrosarcoma cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Evaluation, Preclinical; Fibrosar | 2002 |
Administration of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) and diclofenac in the combination attenuates their anti-tumor activities.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Div | 2003 |
Inhibitory effect of Aspergillus fumigatus extract on matrix metalloproteinases expression.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspergillus fumigatus; Cell Line, Tumor; Dexamethasone; Dic | 2004 |
Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Su | 2005 |
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Tr | 1983 |
The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Division; Diclofenac; Fibrosarcom | 2002 |