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diclofenac and Endophthalmitis

diclofenac has been researched along with Endophthalmitis in 27 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of angiographic cystoid macular edema (CME) after cataract surgery and intraocular lens (IOL) implantation."9.08Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery. ( Bujtar, E; Castoldi, D; Orzalesi, N; Rossetti, L; Torrazza, C, 1996)
"Diclofenac sodium was as effective as the control regimen in controlling postoperative inflammation after cataract surgery."9.08Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema. Italian Diclofenac Study Group. ( , 1997)
"One hundred forty-eight patients were enrolled in a randomized, prospective, placebo-controlled clinical trial evaluating the efficacy of diclofenac sodium (Voltaren Ophthalmic) in reducing ocular inflammation following extracapsular cataract extraction with posterior chamber intraocular lens implantation."9.07Efficacy of diclofenac sodium ophthalmic solution versus placebo in reducing inflammation following cataract extraction and posterior chamber lens implantation. ( Kraff, MC; Martin, RG; Neumann, AC; Weinstein, AJ, 1994)
"The purpose of this study was to analyze ciprofloxacin and lomefloxacin penetration into the anterior eye tissues after topical instillation in healthy rabbits and with experimental Staphylococcus aureus endophthalmitis."7.80Effect of diclofenac on ocular levels of ciprofloxacin and lomefloxacin in rabbits with endophthalmitis. ( Haritova, AM; Krustev, SZ; Rusenova, NV, 2014)
" For prevention of postoperative intraocular pressure (IOP) elevation, carbachol 0."5.08[Minimally inflammatory cataract surgery]. ( Hessemer, V; Schartner, H; Schmidt, KG, 1996)
"To evaluate the effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of angiographic cystoid macular edema (CME) after cataract surgery and intraocular lens (IOL) implantation."5.08Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery. ( Bujtar, E; Castoldi, D; Orzalesi, N; Rossetti, L; Torrazza, C, 1996)
"Diclofenac sodium was as effective as the control regimen in controlling postoperative inflammation after cataract surgery."5.08Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema. Italian Diclofenac Study Group. ( , 1997)
"One hundred forty-eight patients were enrolled in a randomized, prospective, placebo-controlled clinical trial evaluating the efficacy of diclofenac sodium (Voltaren Ophthalmic) in reducing ocular inflammation following extracapsular cataract extraction with posterior chamber intraocular lens implantation."5.07Efficacy of diclofenac sodium ophthalmic solution versus placebo in reducing inflammation following cataract extraction and posterior chamber lens implantation. ( Kraff, MC; Martin, RG; Neumann, AC; Weinstein, AJ, 1994)
"The purpose of this study was to analyze ciprofloxacin and lomefloxacin penetration into the anterior eye tissues after topical instillation in healthy rabbits and with experimental Staphylococcus aureus endophthalmitis."3.80Effect of diclofenac on ocular levels of ciprofloxacin and lomefloxacin in rabbits with endophthalmitis. ( Haritova, AM; Krustev, SZ; Rusenova, NV, 2014)
"In the dosage used, diclofenac was as effective an anti-inflammatory agent for uncomplicated post-cataract inflammation as prednisolone."2.68A comparison of topical diclofenac with prednisolone for postcataract inflammation. ( Brennan, KM; Roberts, CW, 1995)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's20 (74.07)18.2507
2000's3 (11.11)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topete, A1
Serro, AP1
Saramago, B1
Krustev, SZ1
Rusenova, NV1
Haritova, AM1
Waterbury, LD1
Flach, AJ1
Ilic, J1
Gigon, S1
Leuenberger, PM1
Matsuo, K1
Hojou, H1
Honbou, M1
Miyata, N1
Roberts, CW2
Brennan, KM1
Struck, HG1
Schäfer, K1
Foja, C1
Giessler, C1
Lautenschläger, C1
Hessemer, V4
Schmitt, K2
Gwin, TD1
Stewart, WC1
Gwynn, DR1
Othenin-Girard, P1
Tritten, JJ1
Pittet, N2
Herbort, CP2
Kraff, MC1
Martin, RG1
Neumann, AC1
Weinstein, AJ1
Mermoud, A1
Schnyder, C1
Jacobi, A1
Ply, JJ1
Schmidt, KG1
Schartner, H2
Schmidl, B2
Mester, U2
Diestelhorst, M2
Konen, W2
Rossetti, L2
Bellucci, R1
Cillino, S1
Monreale, D1
Bonomi, L1
Ponte, F1
Orzalesi, N2
Raj, PS2
Bujtar, E1
Castoldi, D1
Torrazza, C1
Shepherd, WF1
Fsadni, MG1
Helveston, EM1
Thaller, VT1
Kulshrestha, MK1
Bell, K1
Reddy, MS1
Suneetha, N1
Thomas, RK1
Battu, RR1
Rowland, JM1
Ford, CJ1
Della Puca, RA1
Cash, WD1

Trials

19 trials available for diclofenac and Endophthalmitis

ArticleYear
[Comparison of the anti-inflammatory effect of collyria of dexamethasone and diclofenac].
    Klinische Monatsblatter fur Augenheilkunde, 1984, Volume: 184, Issue:5

    Topics: Aged; Cataract Extraction; Clinical Trials as Topic; Dexamethasone; Diclofenac; Double-Blind Method;

1984
A comparison of topical diclofenac with prednisolone for postcataract inflammation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:6

    Topics: Administration, Topical; Anterior Chamber; Cataract Extraction; Cell Count; Diclofenac; Double-Blind

1995
[Effect of diclofenac and flurbiprofen on the course of inflammation after cataract extraction].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1994, Volume: 91, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Double-Blind Method; Endophthalmiti

1994
[Anti-inflammatory effect of a local combination therapy with diclofenac and prednisolone vs. indomethacin and prednisolone. A laser flare cell photometry study].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1994, Volume: 91, Issue:2

    Topics: Aged; Aqueous Humor; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; End

1994
Dexamethasone versus diclofenac sodium eyedrops to treat inflammation after cataract surgery.
    Journal of cataract and refractive surgery, 1994, Volume: 20, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Cell Count; De

1994
Efficacy of diclofenac sodium ophthalmic solution versus placebo in reducing inflammation following cataract extraction and posterior chamber lens implantation.
    Journal of cataract and refractive surgery, 1994, Volume: 20, Issue:2

    Topics: Aged; Cataract Extraction; Diclofenac; Double-Blind Method; Endophthalmitis; Female; Follow-Up Studi

1994
Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:4

    Topics: Aged; Anterior Eye Segment; Diclofenac; Double-Blind Method; Drug Administration Schedule; Endophtha

1993
Pretreatment with topical diclofenac sodium to decrease postoperative inflammation.
    Ophthalmology, 1996, Volume: 103, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Endophthalmitis; Human

1996
[Anti-inflammatory effects and aqueous humor concentration of various nonsteroidal anti-inflammatory drugs in extracapsular cataract surgery].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 208, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Blood-Retinal Barri

1996
[Minimally inflammatory cataract surgery].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 209, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood-Aqueous Barrier; Carbachol; Dexamethasone; Dichlorphenamide; D

1996
[Minor effect of anti-inflammatory therapy on intraocular inflammation after minimally invasive phacoemulsification].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory

1997
[Laser flare measurement with 3 different nonsteroidal anti-inflammatory drugs after phacoemulsification with posterior chamber lens implantation].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug;

1997
Efficacy and safety of combined diclofenac 0.1% and gentamicin 0.3% eyedrops after phacoemulsification.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, N

1997
Efficacy and tolerance of diclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation.
    Journal of cataract and refractive surgery, 1996, Volume: 22 Suppl 1

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Me

1996
Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery.
    Journal of cataract and refractive surgery, 1996, Volume: 22 Suppl 1

    Topics: Administration, Topical; Aged; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cataract E

1996
Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema. Italian Diclofenac Study Group.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Double-Blind Method;

1997
A clinical evaluation of diclofenac-gentamicin combination eye drops in the control of inflammation after cataract surgery. Diclofenac-Gentamicin versus Gentamicin Study Group.
    Ocular immunology and inflammation, 1998, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; D

1998
The effect of pre-operative topical flurbiprofen or diclofenac on pupil dilatation.
    Eye (London, England), 2000, Volume: 14 ( Pt 4)

    Topics: Adult; Analysis of Variance; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ext

2000
Topical diclofenac sodium for treatment of postoperative inflammation in cataract surgery.
    Indian journal of ophthalmology, 2000, Volume: 48, Issue:3

    Topics: Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cell Count; Dexameth

2000

Other Studies

8 other studies available for diclofenac and Endophthalmitis

ArticleYear
Dual drug delivery from intraocular lens material for prophylaxis of endophthalmitis in cataract surgery.
    International journal of pharmaceutics, 2019, Mar-10, Volume: 558

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Dru

2019
Effect of diclofenac on ocular levels of ciprofloxacin and lomefloxacin in rabbits with endophthalmitis.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:11

    Topics: Administration, Topical; Animals; Anterior Eye Segment; Anti-Bacterial Agents; Anti-Inflammatory Age

2014
Comparison of ketorolac tromethamine, diclofenac sodium, and loteprednol etabonate in an animal model of ocular inflammation.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:3

    Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Diclofenac; Disease Models, Animal; Endophthalmit

2006
Clinical efficacy of diclofenac sodium on postsurgical inflammation after intraocular lens implantation.
    Journal of cataract and refractive surgery, 1995, Volume: 21, Issue:3

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anterior Eye Segment; Betamethasone; Cataract Extr

1995
Filtration surgery in rabbits treated with diclofenac or prednisolone acetate.
    Ophthalmic surgery, 1994, Volume: 25, Issue:4

    Topics: Animals; Combined Modality Therapy; Diclofenac; Endophthalmitis; Glaucoma; Intraocular Pressure; Pre

1994
Decrease of postoperative inflammation with diclofenac sodium.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Acetylcholine; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Drug Combin

1996
Topical steroids not 'standard of care'.
    Binocular vision & strabismus quarterly, 1998, Volume: 13, Issue:2

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Delivery of Health Care; Di

1998
Effects of topical diclofenac sodium in a rabbit model of ocular inflammation and leukotaxis.
    Journal of ocular pharmacology, 1986,Winter, Volume: 2, Issue:1

    Topics: Administration, Topical; Animals; Chemotaxis, Leukocyte; Diclofenac; Disease Models, Animal; Endopht

1986