diclofenac has been researched along with Endocarditis, Bacterial in 2 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
| Excerpt | Relevance | Reference |
|---|---|---|
| "05) the area under the curve in tissue-cage fluid of ceftriaxone and cefotiam-treated animals, and the terminal half-life of ceftriaxone in their sera (3." | 1.27 | Enhancement of the therapeutic effect of cephalosporins in experimental endocarditis by altering their pharmacokinetics with diclofenac. ( Brion, N; Carbon, C; Joly, V; Pangon, B; Vallois, JM, 1988) |
| " Given once daily at a therapeutic dosage (30 mg/kg) for 4 days, ceftriaxone exhibited good efficacy (log10 CFU/g of vegetation = 2." | 1.27 | Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis. ( Abel, L; Brion, N; Bure, A; Carbon, C; Chau, NP; Contrepois, A; Joly, V; Pangon, B; Vallois, JM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joly, V | 2 |
| Pangon, B | 2 |
| Brion, N | 2 |
| Vallois, JM | 2 |
| Carbon, C | 2 |
| Abel, L | 1 |
| Bure, A | 1 |
| Chau, NP | 1 |
| Contrepois, A | 1 |
2 other studies available for diclofenac and Endocarditis, Bacterial
| Article | Year |
|---|---|
Enhancement of the therapeutic effect of cephalosporins in experimental endocarditis by altering their pharmacokinetics with diclofenac.
Topics: Animals; Cefmenoxime; Cefotaxime; Cefotiam; Ceftriaxone; Diclofenac; Drug Synergism; Endocarditis, B | 1988 |
Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis.
Topics: Animals; Ceftriaxone; Diclofenac; Diffusion; Endocarditis, Bacterial; Escherichia coli Infections; M | 1987 |