diclofenac has been researched along with Crohn Disease in 6 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of severe colitis from diclofenac (Voltaren), one of a number of nonsteroidal anti-inflammatory drugs (NSAIDs) that can cause colonic injury." | 7.69 | A case of diclofenac-induced colitis with focal granulomatous change. ( Baert, F; Blackstone, MO; Hart, J, 1995) |
| "We report a case of severe colitis from diclofenac (Voltaren), one of a number of nonsteroidal anti-inflammatory drugs (NSAIDs) that can cause colonic injury." | 3.69 | A case of diclofenac-induced colitis with focal granulomatous change. ( Baert, F; Blackstone, MO; Hart, J, 1995) |
| "Two women, aged 21 and 44 years, developed ileocolitis and proctocolitis, respectively, lasting for several weeks after taking non-steroidal anti-inflammatory drugs (Diclofenac; Pyrazinebutazone)." | 3.67 | [Side effects of non-steroidal antirheumatic agents on the lower intestinal tract]. ( Filippini, L; Ritschard, T, 1986) |
| " While these drugs effectively reduce musculoskeletal pain and stiffness, long-term use is limited by gastrointestinal (GI) adverse effects (AEs) and disease exacerbation." | 2.50 | Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease. ( Hu, RW; Li, HY; Li, JS; Miao, XP; Ouyang, Q; Zhang, Y, 2014) |
| "First, patients with quiescent Crohn's disease and ulcerative colitis received the non-NSAID analgesic acetaminophen (n = 26) and the conventional NSAIDs naproxen (n = 32), diclofenac (n = 29), and indomethacin (n = 22) for 4 weeks." | 1.33 | Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. ( Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miao, XP | 1 |
| Li, JS | 1 |
| Ouyang, Q | 1 |
| Hu, RW | 1 |
| Zhang, Y | 1 |
| Li, HY | 1 |
| Takeuchi, K | 1 |
| Smale, S | 1 |
| Premchand, P | 1 |
| Maiden, L | 1 |
| Sherwood, R | 1 |
| Thjodleifsson, B | 1 |
| Bjornsson, E | 1 |
| Bjarnason, I | 1 |
| Baert, F | 1 |
| Hart, J | 1 |
| Blackstone, MO | 1 |
| Kirsch, M | 1 |
| Witham, R | 1 |
| Ritschard, T | 1 |
| Filippini, L | 1 |
1 review available for diclofenac and Crohn Disease
| Article | Year |
|---|---|
Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Crohn Disease; Cyclooxygena | 2014 |
5 other studies available for diclofenac and Crohn Disease
| Article | Year |
|---|---|
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ul | 2006 |
A case of diclofenac-induced colitis with focal granulomatous change.
Topics: Aged; Colitis; Crohn Disease; Diagnosis, Differential; Diclofenac; Female; Granuloma; Humans | 1995 |
Nonsteroidal antiinflammatory drug colopathy: mimicry of Crohn's disease and colon carcinoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Colonic Neoplasms; Crohn Disease; Diagnos | 1997 |
Voltaren (diclofenac sodium)-induced ileocolitis.
Topics: Aged; Aged, 80 and over; Crohn Disease; Diclofenac; Female; Humans; Middle Aged | 1991 |
[Side effects of non-steroidal antirheumatic agents on the lower intestinal tract].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Crohn Disease; Diclofenac; Female; Humans; | 1986 |