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diclofenac and Corneal Diseases

diclofenac has been researched along with Corneal Diseases in 23 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Corneal Diseases: Diseases of the cornea.

Research Excerpts

ExcerptRelevanceReference
"We report a case of acute corneal melt with perforation in a patient with keratoconus after collagen crosslinking treatment and the use of topical diclofenac and proparacaine eyedrops."7.76Diclofenac-induced acute corneal melt after collagen crosslinking for keratoconus. ( Gokhale, NS; Vemuganti, GK, 2010)
"We report a case of acute corneal melt with perforation in a patient with keratoconus after collagen crosslinking treatment and the use of topical diclofenac and proparacaine eyedrops."3.76Diclofenac-induced acute corneal melt after collagen crosslinking for keratoconus. ( Gokhale, NS; Vemuganti, GK, 2010)
"The diclofenac-treated group showed a statistically significant decrease in corneal sensitivity (p < 0."2.69The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects. ( Aragona, P; Ferreri, G; Laganà, E; Spinella, R; Tripodi, G, 2000)
"Cryptosporidiosis has been reported in more than 30 avian species worldwide."1.36Cryptosporidium baileyi infection associated with an outbreak of ocular and respiratory disease in otus owls (Otus scops) in a rehabilitation centre. ( Ares-Mazas, E; Caccio, SM; Darwich, L; Gomez-Couso, H; Leiva, M; Martin-Vazquez, S; Molina-Lopez, RA; Ramis, A, 2010)
" Dosing and duration varied, but in all 3 cases diclofenac was used at least 4 times a day for at least 3 days after LASIK."1.32Histopathology of corneal melting associated with diclofenac use after refractive surgery. ( Hsu, JK; Johnston, WT; McDonnell, PJ; Pangalinan, R; Rao, N; Read, RW; Smith, RE, 2003)
"Substance P is a normal component of human tears."1.32Substance P in human tears. ( Kawai, M; Mashima, Y; Nishida, T; Ogata, M; Yamada, M, 2003)
"Keratitis was unresponsive to diclophenac sodium eyedrops with respect to healing time and end result."1.31Ocular findings in a measles epidemic among young adults. ( Güler, C; Irkeç, M; Kayikçioglu, O; Kir, E; Söyler, M, 2000)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's17 (73.91)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sandmeyer, LS1
Bauer, BS1
Grahn, BH1
Ornek, K1
Yalçindağ, FN1
Ozdemir, O1
Gokhale, NS1
Vemuganti, GK1
Molina-Lopez, RA1
Ramis, A1
Martin-Vazquez, S1
Gomez-Couso, H1
Ares-Mazas, E1
Caccio, SM1
Leiva, M1
Darwich, L1
Hauser, D1
Buckelman, A1
Katz, H1
Rechtman, E1
Klayman, G1
Pollack, A1
Hsu, JK1
Johnston, WT1
Read, RW1
McDonnell, PJ1
Pangalinan, R1
Rao, N1
Smith, RE1
Gabison, EE1
Chastang, P1
Menashi, S1
Mourah, S1
Doan, S1
Oster, M1
Mauviel, A1
Hoang-Xuan, T1
Yamada, M1
Ogata, M1
Kawai, M1
Mashima, Y1
Nishida, T1
Zanini, M1
Savini, G1
Barboni, P1
Shimazaki, J1
Saito, H1
Yang, HY1
Toda, I1
Fujishima, H1
Tsubota, K1
Haynes, RJ1
Walker, S1
Kirkpatrick, JN1
Ueda, M1
Sugatani, J1
Unezaki, S1
Ito, Y1
Miki, H1
Uyama, M1
Ito, S1
Kayikçioglu, O1
Kir, E1
Söyler, M1
Güler, C1
Irkeç, M1
Aragona, P1
Tripodi, G1
Spinella, R1
Laganà, E1
Ferreri, G1
Flach, A2
Lin, JC1
Rapuano, CJ1
Laibson, PR1
Eagle, RC1
Cohen, EJ1
Tabbara, KF1
Hoffman, J1
Gayton, JL1
Masket, S1
Flach, AJ1
Hargrave, SL1
Jung, JC1
Fini, ME1
Gelender, H1
Cather, C1
Guidera, A1
Udell, I1
Fisher, S1
Jester, JV1
Bowman, RW1
McCulley, JP1
Cavanagh, HD1

Trials

2 trials available for diclofenac and Corneal Diseases

ArticleYear
Topical diclofenac relieves pain from corneal rust ring.
    Eye (London, England), 1996, Volume: 10 ( Pt 4)

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofena

1996
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
    Eye (London, England), 2000, Volume: 14 ( Pt 2)

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; E

2000

Other Studies

21 other studies available for diclofenac and Corneal Diseases

ArticleYear
Diagnostic Ophthalmology. Corneal lesion in a cat.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cat Diseases; Cats; Cicatri

2015
Corneal melting associated with a fixed-dose combination of diclofenac 0.1% plus tobramycin 0.3% following cataract surgery.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:8

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extracti

2008
Diclofenac-induced acute corneal melt after collagen crosslinking for keratoconus.
    Cornea, 2010, Volume: 29, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Collagen; Corneal Diseases; Corneal Perforation; Corneal St

2010
Cryptosporidium baileyi infection associated with an outbreak of ocular and respiratory disease in otus owls (Otus scops) in a rehabilitation centre.
    Avian pathology : journal of the W.V.P.A, 2010, Volume: 39, Issue:3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blepharoptosis; Conjuncti

2010
Keratic precipitates and iris nodules after uneventful phacoemulsification in diabetic patients.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diabetes Complications; Diabetes Me

2002
Histopathology of corneal melting associated with diclofenac use after refractive surgery.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Female; Humans

2003
Late corneal perforation after photorefractive keratectomy associated with topical diclofenac: involvement of matrix metalloproteinases.
    Ophthalmology, 2003, Volume: 110, Issue:8

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Collagen Type III; Collagen Type I

2003
Substance P in human tears.
    Cornea, 2003, Volume: 22, Issue:7 Suppl

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatog

2003
Corneal melting associated with topical diclofenac use after laser-assisted subepithelial keratectomy.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:9

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofena

2006
Persistent epithelial defect following penetrating keratoplasty: an adverse effect of diclofenac eyedrops.
    Cornea, 1995, Volume: 14, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Epitheli

1995
Involvement of prostaglandin E2 in rabbit corneal injury by anterior segment ischaemia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:3

    Topics: Alprostadil; Animals; Anterior Eye Segment; Aqueous Humor; Cornea; Corneal Diseases; Corneal Edema;

1997
Ocular findings in a measles epidemic among young adults.
    Ocular immunology and inflammation, 2000, Volume: 8, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Conjunctiva; Conjunctivitis;

2000
Topically applied nonsteroidal anti-inflammatory drugs and corneal problems: an interim review and comment.
    Ophthalmology, 2000, Volume: 107, Issue:7

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea; Corne

2000
Corneal melting associated with use of topical nonsteroidal anti-inflammatory drugs after ocular surgery.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:8

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea;

2000
Peripheral corneal infiltrates following oral diclofenac administration.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:10

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac;

2000
Truth and consequences.
    Ophthalmology, 2001, Volume: 108, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Health Surveys; Human

2001
Truth and consequences.
    Ophthalmology, 2001, Volume: 108, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Humans; Product Surve

2001
Truth and consequences.
    Ophthalmology, 2001, Volume: 108, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofenac; Health Surveys; Human

2001
Additional factors linking corneal melting to topical nonsteroidal anti-inflammatory drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:7

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Diseases; Diclofen

2001
Corneal melts associated with topically applied nonsteroidal anti-inflammatory drugs.
    Transactions of the American Ophthalmological Society, 2001, Volume: 99

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ca

2001
Possible role of the vitamin E solubilizer in topical diclofenac on matrix metalloproteinase expression in corneal melting: an analysis of postoperative keratolysis.
    Ophthalmology, 2002, Volume: 109, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ca

2002