diclofenac has been researched along with Cell Transformation, Neoplastic in 4 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diclofenac was applied topically on the backs of hairless, female, C3." | 1.37 | High death rate in mice treated topically with diclofenac. ( Lerche, CM; Philipsen, PA; Poulsen, T; Wulf, HC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, S | 1 |
| Ghanghas, P | 1 |
| Rana, C | 1 |
| Sanyal, SN | 1 |
| Mücke, T | 1 |
| Gentz, I | 1 |
| Kanatas, A | 1 |
| Ritschl, LM | 1 |
| Mitchell, DA | 1 |
| Wolff, KD | 1 |
| Deppe, H | 1 |
| Dirschka, T | 1 |
| Bierhoff, E | 1 |
| Pflugfelder, A | 1 |
| Garbe, C | 1 |
| Lerche, CM | 1 |
| Philipsen, PA | 1 |
| Poulsen, T | 1 |
| Wulf, HC | 1 |
2 trials available for diclofenac and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Clinical trial analyzing the impact of continuous defocused CO2 laser vaporisation on the malignant transformation of erosive oral lichen planus.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cell T | 2015 |
Topical 3.0% diclofenac in 2.5% hyaluronic acid gel induces regression of cancerous transformation in actinic keratoses.
Topics: Adjuvants, Immunologic; Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, | 2010 |
2 other studies available for diclofenac and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Celecoxib; Cell Transformation, | 2017 |
High death rate in mice treated topically with diclofenac.
Topics: Animals; Body Weight; Cell Transformation, Neoplastic; Diclofenac; Female; Kaplan-Meier Estimate; Mi | 2011 |