diclofenac has been researched along with Cataract in 22 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate and compare regulation of diabetes mellitus (DM) in dogs with cataracts and well-controlled DM that received an ophthalmic preparation of prednisolone acetate versus diclofenac sodium." | 9.30 | Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium. ( Bello, NM; Fentiman, KE; Huey, JA; KuKanich, KS; Meekins, JM; Rankin, AJ; Schermerhorn, T, 2019) |
| "Patients preoperatively treated with diclofenac had significantly lower intraocular levels of IL-12 and a lower increase in CFT, which indicates that a combination of preoperative and postoperative treatment with a topical NSAID may lower the incidence of postoperative macular edema in patients with diabetic retinopathy." | 9.24 | Effect of preoperative topical diclofenac on intraocular interleukin-12 concentration and macular edema after cataract surgery in patients with diabetic retinopathy: a randomized controlled trial. ( Jukić, T; Matas, A; Medić, A; Sapunar, A; Vukojević, K; Znaor, L, 2017) |
| "To compare the effects of topical diclofenac and betamethasone on postoperative inflammation after combined sutureless cataract and vitreoretinal surgery in patients with macular hole (MH), epiretinal membrane (ERM), diabetic macular edema (DME), and rhegmatogenous retinal detachment (RRD)." | 9.22 | Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases. ( Kotake, O; Motohashi, R; Nakagawa, H; Noma, H; Shimura, M; Yasuda, K, 2016) |
| "Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation." | 9.19 | Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014) |
| "The purpose of our study was to evaluate the effectiveness of preoperative and postoperative addition of topical diclofenac to chloramphenicol/dexamethasone in patients undergoing uneventful phacoemulsification cataract surgery." | 9.16 | Is topical diclofenac essential before and after uneventful phacoemulsification cataract surgery? ( Chatziralli, IP; Moschos, MM; Pantazis, P; Rouvas, AA; Sergentanis, TN, 2012) |
| "This study compares the effect of topical diclofenac with that of betamethasone against postoperative cystoid macular edema (CME) following cataract surgery in patients with non- and mild nonproliferative diabetic retinopathy." | 9.12 | Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes. ( Nakazawa, T; Nishida, K; Shimura, M; Yasuda, K, 2007) |
| "1% diclofenac eye drops for the management of postoperative inflammation after cataract surgery in patients with nonproliferative diabetic retinopathy and in normal controls." | 7.78 | A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy. ( Miyazawa, A; Shimura, M; Yasuda, K, 2012) |
| "To evaluate and compare regulation of diabetes mellitus (DM) in dogs with cataracts and well-controlled DM that received an ophthalmic preparation of prednisolone acetate versus diclofenac sodium." | 5.30 | Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium. ( Bello, NM; Fentiman, KE; Huey, JA; KuKanich, KS; Meekins, JM; Rankin, AJ; Schermerhorn, T, 2019) |
| "Patients preoperatively treated with diclofenac had significantly lower intraocular levels of IL-12 and a lower increase in CFT, which indicates that a combination of preoperative and postoperative treatment with a topical NSAID may lower the incidence of postoperative macular edema in patients with diabetic retinopathy." | 5.24 | Effect of preoperative topical diclofenac on intraocular interleukin-12 concentration and macular edema after cataract surgery in patients with diabetic retinopathy: a randomized controlled trial. ( Jukić, T; Matas, A; Medić, A; Sapunar, A; Vukojević, K; Znaor, L, 2017) |
| "To compare the effects of topical diclofenac and betamethasone on postoperative inflammation after combined sutureless cataract and vitreoretinal surgery in patients with macular hole (MH), epiretinal membrane (ERM), diabetic macular edema (DME), and rhegmatogenous retinal detachment (RRD)." | 5.22 | Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases. ( Kotake, O; Motohashi, R; Nakagawa, H; Noma, H; Shimura, M; Yasuda, K, 2016) |
| "Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation." | 5.19 | Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014) |
| "Both diclofenac and pranoprofen treatment inhibit surgical-induced miosis." | 5.19 | Effect of topical nonsteroidal anti-inflammatory drugs and nuclear hardness on maintenance of mydriasis during phacoemulsification surgery. ( Liu, C; Liu, L; Liu, Y; Wu, M; Ye, S; Zhang, W, 2014) |
| "In this preliminary study, diclofenac sodium is at least as good as topical dexamethasone phosphate for glaucoma patients undergoing two-site combined phacotrabeculectomy with mitomycin C." | 5.17 | Postoperative treatment with topical diclofenac versus topical dexamethasone after combined phacotrabeculectomy with mitomycin C. ( Goldenfeld, M; Kalev-Landoi, M; Katz, G; Levkovitch-Verbin, H, 2013) |
| "The purpose of our study was to evaluate the effectiveness of preoperative and postoperative addition of topical diclofenac to chloramphenicol/dexamethasone in patients undergoing uneventful phacoemulsification cataract surgery." | 5.16 | Is topical diclofenac essential before and after uneventful phacoemulsification cataract surgery? ( Chatziralli, IP; Moschos, MM; Pantazis, P; Rouvas, AA; Sergentanis, TN, 2012) |
| "This study compares the effect of topical diclofenac with that of betamethasone against postoperative cystoid macular edema (CME) following cataract surgery in patients with non- and mild nonproliferative diabetic retinopathy." | 5.12 | Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes. ( Nakazawa, T; Nishida, K; Shimura, M; Yasuda, K, 2007) |
| "Two hundred eighty-five patients who underwent cataract surgery were prospectively randomized to receive treatment with topical dexamethasone or diclofenac for 1 month." | 5.12 | Effect of dexamethasone eyedrops on blood glucose profile. ( Avisar, R; Bahar, I; Eldar, I; Erenberg, M; Gaton, D; Rosenblat, I; Weinberger, D, 2007) |
| "Topical instillation of diclofenac, dexamethasone, or a placebo in the immediate period after phacoemulsification and IOL implantation did not seem to influence the formation of PCO 2 years after cataract surgery." | 5.11 | Posterior capsule opacification after phacoemulsification in patients with postoperative steroidal and nonsteroidal treatment. ( Laurell, CG; Zaczek, A; Zetterström, C, 2004) |
| "This study did not demonstrate a difference in the ability of diclofenac or ketorolac ophthalmic solutions to prevent PCO following cataract extraction and implantation of an intraocular lens." | 5.09 | Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation. ( Dolan, BJ; Flach, AJ, 2000) |
| "1% diclofenac eye drops for the management of postoperative inflammation after cataract surgery in patients with nonproliferative diabetic retinopathy and in normal controls." | 3.78 | A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy. ( Miyazawa, A; Shimura, M; Yasuda, K, 2012) |
| "We investigated the effects of diclofenac sodium and indomethacin on the proliferation of and collagen synthesis by lens epithelial cells (LECs) of human cataracts in culture." | 3.69 | Effects of diclofenac sodium and indomethacin on proliferation and collagen synthesis of lens epithelial cells in vitro. ( Fujiwara, T; Nishi, K; Nishi, O; Shirasawa, E, 1995) |
| "Diclofenac was the most likely to reduce the odds of developing CME compared with bromfenac and nepafenac." | 3.01 | Comparison of the efficacy and safety of non-steroidal anti-inflammatory drugs and corticosteroid drugs for prevention of cystoid macular edema after cataract surgery. ( Chen, X; Li, SS; Wang, HH; Wang, YL; Zhang, DW, 2023) |
| "Treatment with diclofenac sodium and bromfenac sodium ophthalmic solution prevented progression of anterior capsule contraction and PCO." | 1.35 | Efficacy of ophthalmic nonsteroidal antiinflammatory drugs in suppressing anterior capsule contraction and secondary posterior capsule opacification. ( Aose, M; Gotoh, N; Matsui, E; Matsushima, H; Mukai, K; Nagata, M; Satoshi, W; Senoo, T; Wataru, T, 2009) |
| "Diclofenac sodium has been demonstrated to be effective in preventing proliferation of lens epithelial cells both in vitro and in animal studies." | 1.33 | Effect of diclofenac on prevention of posterior capsule opacification in human eyes. ( Bozkurt, E; Ermis, S; Inan, UU; Oztürk, F; Yaman, S, 2006) |
| "Diclofenac was less effective but also reduced PCO." | 1.31 | Prevention of posterior capsule opacification by intraoperative single-dose pharmacologic agents. ( Emiroğlu, L; Güler, C; Ilker, SS; Kaynak, S; Kurt, E; Ozer, E; Oztürk, F, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Li, SS | 1 |
| Wang, HH | 1 |
| Wang, YL | 1 |
| Zhang, DW | 1 |
| Chen, X | 1 |
| Wingert, AM | 2 |
| Liu, SH | 2 |
| Lin, JC | 2 |
| Sridhar, J | 2 |
| Rankin, AJ | 1 |
| KuKanich, KS | 1 |
| Schermerhorn, T | 1 |
| Bello, NM | 1 |
| Huey, JA | 1 |
| Fentiman, KE | 1 |
| Meekins, JM | 1 |
| Osaki, T | 1 |
| Ozaki, M | 1 |
| Takamura, N | 1 |
| Ogata, K | 1 |
| Tokunaga, J | 1 |
| Setoguchi, N | 1 |
| Arimori, K | 1 |
| Liu, C | 1 |
| Liu, Y | 1 |
| Ye, S | 1 |
| Liu, L | 1 |
| Zhang, W | 1 |
| Wu, M | 1 |
| Yasuda, K | 3 |
| Motohashi, R | 1 |
| Kotake, O | 1 |
| Nakagawa, H | 1 |
| Noma, H | 1 |
| Shimura, M | 3 |
| Medić, A | 1 |
| Jukić, T | 1 |
| Matas, A | 1 |
| Vukojević, K | 1 |
| Sapunar, A | 1 |
| Znaor, L | 1 |
| Mukai, K | 1 |
| Matsushima, H | 1 |
| Gotoh, N | 1 |
| Aose, M | 1 |
| Satoshi, W | 1 |
| Wataru, T | 1 |
| Matsui, E | 1 |
| Nagata, M | 1 |
| Senoo, T | 1 |
| Levkovitch-Verbin, H | 1 |
| Katz, G | 1 |
| Kalev-Landoi, M | 1 |
| Goldenfeld, M | 1 |
| Miyazawa, A | 1 |
| Moschos, MM | 1 |
| Chatziralli, IP | 1 |
| Pantazis, P | 1 |
| Rouvas, AA | 1 |
| Sergentanis, TN | 1 |
| Zaczek, A | 1 |
| Laurell, CG | 1 |
| Zetterström, C | 1 |
| Barequet, IS | 1 |
| Wygnanski-Jaffe, T | 1 |
| Sachs, D | 1 |
| Symonds, JG | 1 |
| Lovicu, FJ | 1 |
| Chamberlain, CG | 1 |
| Neumayer, T | 1 |
| Buehl, W | 1 |
| Findl, O | 1 |
| Inan, UU | 1 |
| Bozkurt, E | 1 |
| Oztürk, F | 2 |
| Ermis, S | 1 |
| Yaman, S | 1 |
| Nakazawa, T | 1 |
| Nishida, K | 1 |
| Bahar, I | 1 |
| Rosenblat, I | 1 |
| Erenberg, M | 1 |
| Eldar, I | 1 |
| Gaton, D | 1 |
| Avisar, R | 1 |
| Weinberger, D | 1 |
| Nishi, O | 1 |
| Nishi, K | 1 |
| Fujiwara, T | 1 |
| Shirasawa, E | 1 |
| Orhan, H | 1 |
| Marol, S | 1 |
| Hepşen, IF | 1 |
| Sahin, G | 1 |
| Flach, AJ | 1 |
| Dolan, BJ | 1 |
| Kaynak, S | 1 |
| Kurt, E | 1 |
| Emiroğlu, L | 1 |
| Ozer, E | 1 |
| Ilker, SS | 1 |
| Güler, C | 1 |
2 reviews available for diclofenac and Cataract
| Article | Year |
|---|---|
Comparison of the efficacy and safety of non-steroidal anti-inflammatory drugs and corticosteroid drugs for prevention of cystoid macular edema after cataract surgery.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Cataract; Cataract | 2023 |
Non-steroidal anti-inflammatory agents for treating cystoid macular edema following cataract surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Diclofenac; Female; Humans; Ketorolac; Macu | 2022 |
Non-steroidal anti-inflammatory agents for treating cystoid macular edema following cataract surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Diclofenac; Female; Humans; Ketorolac; Macu | 2022 |
Non-steroidal anti-inflammatory agents for treating cystoid macular edema following cataract surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Diclofenac; Female; Humans; Ketorolac; Macu | 2022 |
Non-steroidal anti-inflammatory agents for treating cystoid macular edema following cataract surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Diclofenac; Female; Humans; Ketorolac; Macu | 2022 |
12 trials available for diclofenac and Cataract
| Article | Year |
|---|---|
Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium.
Topics: Animals; Cataract; Diabetes Complications; Diabetes Mellitus; Diclofenac; Dog Diseases; Dogs; Double | 2019 |
Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.
Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Binding Sites; C | 2014 |
Effect of topical nonsteroidal anti-inflammatory drugs and nuclear hardness on maintenance of mydriasis during phacoemulsification surgery.
Topics: Administration, Ophthalmic; Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Cataract; Di | 2014 |
Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases.
Topics: Administration, Topical; Aged; Betamethasone; Cataract; Diclofenac; Female; Humans; Inflammation; Ma | 2016 |
Effect of preoperative topical diclofenac on intraocular interleukin-12 concentration and macular edema after cataract surgery in patients with diabetic retinopathy: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Aqueous Hu | 2017 |
Postoperative treatment with topical diclofenac versus topical dexamethasone after combined phacotrabeculectomy with mitomycin C.
Topics: Administration, Topical; Aged; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract; | 2013 |
Is topical diclofenac essential before and after uneventful phacoemulsification cataract surgery?
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, | 2012 |
Posterior capsule opacification after phacoemulsification in patients with postoperative steroidal and nonsteroidal treatment.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract; | 2004 |
Effect of topical prednisolone and diclofenac on the short-term change in morphology of posterior capsular opacification.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ca | 2006 |
Diclofenac prevents an early event of macular thickening after cataract surgery in patients with diabetes.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents | 2007 |
Effect of dexamethasone eyedrops on blood glucose profile.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Capillaries; | 2007 |
Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extraction; Chi | 2000 |
8 other studies available for diclofenac and Cataract
| Article | Year |
|---|---|
Efficacy of ophthalmic nonsteroidal antiinflammatory drugs in suppressing anterior capsule contraction and secondary posterior capsule opacification.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Betamethasone; Bromobenzenes; Catar | 2009 |
A comparison of preservative-free diclofenac and preserved diclofenac eye drops after cataract surgery in patients with diabetic retinopathy.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Case-Control Studies; Cataract; Cataract Extracti | 2012 |
Effect of diclofenac versus dexamethasone on posterior capsule opacification.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Dexamethasone; Diclofenac; Glucocorticoids; Human | 2004 |
Differing effects of dexamethasone and diclofenac on posterior capsule opacification-like changes in a rat lens explant model.
Topics: Actins; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cell S | 2006 |
Effect of diclofenac on prevention of posterior capsule opacification in human eyes.
Topics: Aged; Cataract; Cell Proliferation; Diclofenac; Epithelial Cells; Female; Glucocorticoids; Humans; I | 2006 |
Effects of diclofenac sodium and indomethacin on proliferation and collagen synthesis of lens epithelial cells in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cell Division; Cells, Cultured; Collagen; Cycloox | 1995 |
Effects of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats.
Topics: Animals; Antioxidants; Catalase; Cataract; Diclofenac; Erythrocytes; Female; Ginkgo biloba; Glutathi | 1999 |
Prevention of posterior capsule opacification by intraoperative single-dose pharmacologic agents.
Topics: Animals; Cataract; Dexamethasone; Diclofenac; Drug Therapy, Combination; Edetic Acid; Epithelial Cel | 2001 |