diclofenac has been researched along with Cardiotoxicity in 6 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the influence of diclofenac sodium (DIC) treatment on tilmicosin (TIL) prompted cardiotoxicity, forty albino rats were randomly divided into four equal groups: control, TIL group (single subcutaneous injection of 75 mg/kg BW tilmicosin phosphate 30%), TIL + DIC group (single subcutaneous injection of tilmicosin phosphate 30% and then injection intramuscularly of 13." | 7.88 | Impact of Diclofenac Sodium on Tilmicosin-Induced Acute Cardiotoxicity in Rats (Tilmicosin and Diclofenac Cardiotoxicity). ( Derbalah, AE; Oda, SS, 2018) |
| "To assess the influence of diclofenac sodium (DIC) treatment on tilmicosin (TIL) prompted cardiotoxicity, forty albino rats were randomly divided into four equal groups: control, TIL group (single subcutaneous injection of 75 mg/kg BW tilmicosin phosphate 30%), TIL + DIC group (single subcutaneous injection of tilmicosin phosphate 30% and then injection intramuscularly of 13." | 3.88 | Impact of Diclofenac Sodium on Tilmicosin-Induced Acute Cardiotoxicity in Rats (Tilmicosin and Diclofenac Cardiotoxicity). ( Derbalah, AE; Oda, SS, 2018) |
| "Diclofenac (DIC) is a commonly prescribed NSAID that is known to increase the risk of cardiovascular diseases." | 1.91 | Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction. ( Chiamvimonvat, N; Gomes, AV; Haddad, M; Hammock, BD; Nader, CE; Overton, J; Ren, L; Sirish, P; Thai, PN; Timofeyev, V; Xu, W; Yang, J, 2023) |
| "The safety of diclofenac (DIC) use in clinical practice has been questioned because of adverse cardiovascular effects." | 1.56 | Calcitriol Reduces Adverse Effects of Diclofenac on Mitochondrial Function in Isolated Rat Heart Mitochondria. ( Atashbar, S; Azizian, S; Khezri, S; Kurdpour, P; Salimi, A; Shaikhgermchi, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thai, PN | 1 |
| Ren, L | 1 |
| Xu, W | 1 |
| Overton, J | 1 |
| Timofeyev, V | 1 |
| Nader, CE | 1 |
| Haddad, M | 1 |
| Yang, J | 1 |
| Gomes, AV | 2 |
| Hammock, BD | 1 |
| Chiamvimonvat, N | 1 |
| Sirish, P | 1 |
| Moore, N | 1 |
| Khezri, S | 1 |
| Atashbar, S | 1 |
| Azizian, S | 1 |
| Shaikhgermchi, Z | 1 |
| Kurdpour, P | 1 |
| Salimi, A | 1 |
| Oda, SS | 1 |
| Derbalah, AE | 1 |
| Abdel-Daim, MM | 1 |
| Eltaysh, R | 1 |
| Hassan, A | 1 |
| Mousa, SA | 1 |
| Ghosh, R | 1 |
| Goswami, SK | 1 |
| Feitoza, LFBB | 1 |
| Hammock, B | 1 |
1 review available for diclofenac and Cardiotoxicity
| Article | Year |
|---|---|
Coronary Risks Associated with Diclofenac and Other NSAIDs: An Update.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiotoxicity; Cardiovascular Diseases; Cyclooxygenase 2 I | 2020 |
5 other studies available for diclofenac and Cardiotoxicity
| Article | Year |
|---|---|
Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotoxicity; Diclofenac; Heart Diseases; Inflam | 2023 |
Calcitriol Reduces Adverse Effects of Diclofenac on Mitochondrial Function in Isolated Rat Heart Mitochondria.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitriol; Cardiotoxicity; Cell Fractionation; Di | 2020 |
Impact of Diclofenac Sodium on Tilmicosin-Induced Acute Cardiotoxicity in Rats (Tilmicosin and Diclofenac Cardiotoxicity).
Topics: Animals; Apoptosis; Biomarkers; Cardiotoxicity; Caspase 3; Chemical and Drug Induced Liver Injury; D | 2018 |
Lycopene Attenuates Tulathromycin and Diclofenac Sodium-Induced Cardiotoxicity in Mice.
Topics: Animals; Biomarkers; Cardiotoxicity; Carotenoids; Creatine Kinase, MB Form; Diclofenac; Disaccharide | 2018 |
Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cardiotoxicity; Cells, Cultured; Diclof | 2016 |