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diclofenac and Carcinoma, Basal Cell

diclofenac has been researched along with Carcinoma, Basal Cell in 10 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)

Research Excerpts

ExcerptRelevanceReference
"Hyaluronan (HA) in combination with diclofenac is currently undergoing clinical trials as a topical preparation in the management of osteoarthritic pain, basal-cell carcinoma and actinic keratosis."4.79Hyaluronan as a drug delivery system for diclofenac: a hypothesis for mode of action. ( Moore, AR; Willoughby, DA, 1995)
"sBCC treated with diclofenac showed a significant decrease in Ki-67 (P < ."2.82The effect of topical diclofenac 3% and calcitriol 3 μg/g on superficial basal cell carcinoma (sBCC) and nodular basal cell carcinoma (nBCC): A phase II, randomized controlled trial. ( Brinkhuizen, T; Frencken, KJ; Hoff, ML; Kelleners-Smeets, NW; Mosterd, K; Nelemans, PJ; Rennspiess, D; van der Horst, MP; van Steensel, MA; Winnepenninckx, VJ; Zur Hausen, A, 2016)
"Chemoprevention of nonmelanoma skin cancer should be considered in patients likely to develop numerous, invasive, or metastatic nonmelanoma skin cancers."2.61Topical and Systemic Modalities for Chemoprevention of Nonmelanoma Skin Cancer. ( Council, ML; Nemer, KM, 2019)
"Basal cell carcinoma is a semi-malignant epithelial skin tumour with a locally destructive growth pattern but a very low tendency to metastases."2.43[Non-surgical therapy of basal cell carcinoma of the head-neck region]. ( Dissemond, J; Grabbe, S, 2006)
"The ability to manage non-melanoma skin cancers and pre-malignant lesions with topical pharmacologic agents is highly compelling."2.42Topical treatment strategies for non-melanoma skin cancer and precursor lesions. ( Fein, H; McGillis, ST, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Collins, A1
Savas, J1
Doerfler, L1
El-Khalawany, M1
Saudi, WM1
Ahmed, E1
Mosbeh, A1
Sameh, A1
Rageh, MA1
Nemer, KM1
Council, ML1
Brinkhuizen, T1
Frencken, KJ1
Nelemans, PJ1
Hoff, ML1
Kelleners-Smeets, NW1
Zur Hausen, A1
van der Horst, MP1
Rennspiess, D1
Winnepenninckx, VJ1
van Steensel, MA1
Mosterd, K1
Micali, G1
Lacarrubba, F1
Dinotta, F1
Massimino, D1
Nasca, MR1
Liebman, TN1
Stein, JA1
Polsky, D1
Peterson, SR1
Goldberg, LH1
McGillis, ST1
Fein, H1
Dissemond, J1
Grabbe, S1
Moore, AR1
Willoughby, DA1

Reviews

6 reviews available for diclofenac and Carcinoma, Basal Cell

ArticleYear
Nonsurgical Treatments for Nonmelanoma Skin Cancer.
    Dermatologic clinics, 2019, Volume: 37, Issue:4

    Topics: Administration, Cutaneous; Anilides; Antineoplastic Agents; Antineoplastic Agents, Immunological; Bi

2019
Topical and Systemic Modalities for Chemoprevention of Nonmelanoma Skin Cancer.
    Dermatologic clinics, 2019, Volume: 37, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Antineoplastic Agents; Carcinoma, Basal Cell; Carci

2019
Treating skin cancer with topical cream.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:9

    Topics: Administration, Topical; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cell; Diclofenac;

2010
Topical treatment strategies for non-melanoma skin cancer and precursor lesions.
    Seminars in cutaneous medicine and surgery, 2004, Volume: 23, Issue:3

    Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Ag

2004
[Non-surgical therapy of basal cell carcinoma of the head-neck region].
    Laryngo- rhino- otologie, 2006, Volume: 85, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplas

2006
Hyaluronan as a drug delivery system for diclofenac: a hypothesis for mode of action.
    International journal of tissue reactions, 1995, Volume: 17, Issue:4

    Topics: Animals; Carcinoma, Basal Cell; Carotid Stenosis; Diclofenac; Drug Delivery Systems; Humans; Hyaluro

1995

Trials

1 trial available for diclofenac and Carcinoma, Basal Cell

ArticleYear
The effect of topical diclofenac 3% and calcitriol 3 μg/g on superficial basal cell carcinoma (sBCC) and nodular basal cell carcinoma (nBCC): A phase II, randomized controlled trial.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:1

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Calcitriol; Carci

2016

Other Studies

3 other studies available for diclofenac and Carcinoma, Basal Cell

ArticleYear
The combined effect of CO
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Carbon Dioxide; Carcinoma, Basal Cell; Diclofenac; Female; Humans; Imiquimod;

2022
Cyclo-oxygenase-2 inhibitors for chemoprevention of nonmelanoma skin cancer: is there a role for these agents?
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:1

    Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Celecoxib; Cyclooxygenase 2 Inhibitors; Cy

2013
New and emerging treatments for nonmelanomas and actinic keratoses.
    Journal of drugs in dermatology : JDD, 2003, Volume: 2, Issue:4

    Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Basal C

2003