diclofenac has been researched along with Carbon Tetrachloride Poisoning in 2 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the acute hepatic failure induced by CCl4 on the pharmacokinetics of diclofenac, which is definitely subject to enterohepatic circulation (EHC) in normal rats, was evaluated." | 3.69 | Influence of laparotomy on disposition kinetics of diclofenac in CCl4-intoxicated rats. ( Fukuyama, T; Nakagawa, T; Tabata, K; Yamaoka, K, 1995) |
| " The present observations suggest that reduction of the pharmacokinetic parameters may lead to drug accumulation in the regenerating-damaged liver with an attendant possible increase in toxic effects." | 1.34 | Pharmacokinetics of diclofenac in rats intoxicated with CCL4, and in the regenerating liver. ( Castañeda-Hernández, G; Favari, L; Muriel, P; Reyes-Gordillo, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reyes-Gordillo, K | 1 |
| Muriel, P | 1 |
| Castañeda-Hernández, G | 1 |
| Favari, L | 1 |
| Fukuyama, T | 1 |
| Yamaoka, K | 1 |
| Tabata, K | 1 |
| Nakagawa, T | 1 |
2 other studies available for diclofenac and Carbon Tetrachloride Poisoning
| Article | Year |
|---|---|
Pharmacokinetics of diclofenac in rats intoxicated with CCL4, and in the regenerating liver.
Topics: Administration, Oral; Alanine Transaminase; alpha-Fetoproteins; Animals; Anti-Inflammatory Agents, N | 2007 |
Influence of laparotomy on disposition kinetics of diclofenac in CCl4-intoxicated rats.
Topics: Animals; Carbon Tetrachloride Poisoning; Diclofenac; Laparotomy; Liver Failure; Male; Rats; Rats, Wi | 1995 |