Page last updated: 2024-10-26

diclofenac and Cancer of Prostate

diclofenac has been researched along with Cancer of Prostate in 13 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Research Excerpts

ExcerptRelevanceReference
"We assessed the analgesic efficacy of levobupivacaine when administered as an adjuvant to diclofenac sodium in prostate biopsy pain management and effects of prostate biopsy on sexual function."9.14'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial. ( Aktoz, T; Atakan, IH; Inci, O; Kaplan, M; Memis, D; Turan, U, 2010)
"We assessed the analgesic efficacy of levobupivacaine when administered as an adjuvant to diclofenac sodium in prostate biopsy pain management and effects of prostate biopsy on sexual function."5.14'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial. ( Aktoz, T; Atakan, IH; Inci, O; Kaplan, M; Memis, D; Turan, U, 2010)
"Patients given diclofenac had significantly lower pain scores than those given placebo (2."5.11Diclofenac suppository analgesia for transrectal ultrasound guided biopsies of the prostate: a double-blind, randomized controlled trial. ( Donaldson, PJ; Habib, MR; Haq, A; Parry, JR; Patel, HR, 2004)
"To evaluate the efficacy of intramuscular injection of 75 mg diclofenac sodium and periprostatic nerve block (PPNB) with 1% lignocaine in controlling pain during transrectal ultrasound (TRUS)-guided prostate biopsy."3.74Control of pain during transrectal ultrasound-guided prostate biopsy: a prospective study comparing two methods. ( Bhomi, KK; Consigliere, DT; Lim, HH; Tiong, HY, 2007)
"Commonly used approaches that are effective to minimise pain or discomfort include intravenous sedoanalgesia, inhalational agents and periprostatic infiltration of local anaesthetic."2.50Current methods of analgesia for transrectal ultrasonography (TRUS)-guided prostate biopsy -- a systematic review. ( Lee, C; Woo, HH, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's6 (46.15)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, C1
Woo, HH1
Aktoz, T1
Kaplan, M1
Turan, U1
Memis, D1
Atakan, IH1
Inci, O1
Hiros, M1
Selimovic, M1
Spahovic, H1
Sadovic, S1
Spuzic-Celic, E1
Inoue, T1
Anai, S1
Onishi, S1
Miyake, M1
Tanaka, N1
Hirayama, A1
Fujimoto, K1
Hirao, Y1
Palayoor, ST1
Tofilon, PJ1
Coleman, CN1
Tsuda, H1
Naito, A1
Kim, CK1
Fukamachi, K1
Nomoto, H1
Moore, MA1
Haq, A1
Patel, HR1
Habib, MR1
Donaldson, PJ1
Parry, JR1
Bach, T1
Tauber, R1
Bhomi, KK1
Lim, HH1
Consigliere, DT1
Tiong, HY1
Rodríguez Carballeira, M1
Coll Roldua, I1
Muñoz Rodríguez, FJ1
Bastus Piulats, R1
Cirera Noguera, L1
Espinós Pérez, JC1
Zhou, D1
Lu, Y1
Steiner, MS1
Dalton, JT1
Fainsinger, RL1
Miller, MJ1
Bruera, E1
Stiefel, F1
Morant, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anorectal Application of 5% Lidocaine Cream Reduces Pain Prior to Periprostatic Nerve Block During Transrectal Ultrasound Guided Biopsy: Randomized, Prospective Controlled Study[NCT04064047]284 participants (Actual)Interventional2016-12-31Completed
Diclofenac Suppository As a Preemptive Analgesia in Ultrasound Guided Biopsy of Prostate: Randomized Controlled Trial[NCT01939743]Phase 2100 participants (Actual)Interventional2011-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for diclofenac and Cancer of Prostate

ArticleYear
Current methods of analgesia for transrectal ultrasonography (TRUS)-guided prostate biopsy -- a systematic review.
    BJU international, 2014, Volume: 113 Suppl 2

    Topics: Administration, Rectal; Analgesia; Anesthesia, Local; Anesthetics, Local; Biopsy; Diclofenac; Gels;

2014
Carcinogenesis and its modification by environmental endocrine disruptors: in vivo experimental and epidemiological findings.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:6

    Topics: Animals; Breast Neoplasms; DDT; Diclofenac; Endocrine System; Environmental Pollutants; Epidemiologi

2003

Trials

4 trials available for diclofenac and Cancer of Prostate

ArticleYear
'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial.
    Andrologia, 2010, Volume: 42, Issue:1

    Topics: Aged; Analgesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Bupiva

2010
Transrectal ultrasound-guided prostate biopsy, periprostatic local anesthesia and pain tolerance.
    Bosnian journal of basic medical sciences, 2010, Volume: 10, Issue:1

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Diclofenac; Human

2010
Diclofenac suppository analgesia for transrectal ultrasound guided biopsies of the prostate: a double-blind, randomized controlled trial.
    The Journal of urology, 2004, Volume: 171, Issue:4

    Topics: Aged; Analgesia; Biopsy, Needle; Diclofenac; Double-Blind Method; Humans; Male; Pain; Prospective St

2004
[Diclofenac during prostate needle biopsy. Significant pain reduction].
    Der Urologe. Ausg. A, 2006, Volume: 45, Issue:3

    Topics: Analgesics; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Diclofenac;

2006

Other Studies

7 other studies available for diclofenac and Cancer of Prostate

ArticleYear
Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model.
    BMC urology, 2013, Jan-05, Volume: 13

    Topics: Adenocarcinoma; Administration, Topical; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; C

2013
Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-01, Volume: 9, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tu

2003
Control of pain during transrectal ultrasound-guided prostate biopsy: a prospective study comparing two methods.
    Urologia internationalis, 2007, Volume: 79, Issue:4

    Topics: Aged; Biopsy, Needle; Case-Control Studies; Diclofenac; Humans; Injections, Intramuscular; Lidocaine

2007
[Colitis induced by non-steroidal anti-inflammatory agents].
    Anales de medicina interna (Madrid, Spain : 1984), 1995, Volume: 12, Issue:10

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Colitis; Diarrhea; Diclofenac; Humans

1995
Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Aryl Hydrocarbon Hydroxylases; Biotransformation; Blotting, Weste

2000
Morphine intoxication during acute reversible renal insufficiency.
    Journal of palliative care, 1992,Summer, Volume: 8, Issue:2

    Topics: Acute Kidney Injury; Aged; Bone Neoplasms; Diclofenac; Drug Therapy, Combination; Humans; Male; Morp

1992
Morphine intoxication during acute reversible renal insufficiency.
    Journal of palliative care, 1991,Winter, Volume: 7, Issue:4

    Topics: Acute Kidney Injury; Aged; Bone Neoplasms; Diclofenac; Humans; Male; Morphine; Pain; Poisoning; Pros

1991