diclofenac has been researched along with Bone Cancer in 10 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metastatic bone cancer pain is one of the most common clinical cancer pains and is caused by many factors." | 6.84 | Combined application of diclofenac and celecoxib with an opioid yields superior efficacy in metastatic bone cancer pain: a randomized controlled trial. ( Liu, Z; Liu, ZL; Shen, XH; Tian, YZ; Xu, Y, 2017) |
| "In this trial, 20 patients suffering from bone metastasis pain received diclofenac, a non-steroid anti-inflammatory agent, by continuous IV infusion." | 3.67 | [Efficacy of diclofenac continuous perfusion in hyperalgic bone metastases. Apropos of 20 cases treated at Gustave Roussy Institute]. ( Ammarguellat, H; Benahmed, M; Court, B; Kple Faget, P; Pichard, E; Wibault, P, 1988) |
| "Metastatic bone cancer pain is one of the most common clinical cancer pains and is caused by many factors." | 2.84 | Combined application of diclofenac and celecoxib with an opioid yields superior efficacy in metastatic bone cancer pain: a randomized controlled trial. ( Liu, Z; Liu, ZL; Shen, XH; Tian, YZ; Xu, Y, 2017) |
| "Cancer-induced bone pain is described as dull, aching ongoing pain." | 1.42 | Behavioral and neurochemical analysis of ongoing bone cancer pain in rats. ( King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY, 2015) |
| "Cancer pain is one of the most severe types of chronic pain, and the most common cancer pain is bone cancer pain." | 1.38 | Targeting A-type K(+) channels in primary sensory neurons for bone cancer pain in a rat model. ( Duan, KZ; Mei, YA; Xu, Q; Zhang, XM; Zhang, YQ; Zhao, ZQ, 2012) |
| "Chronic pain resulting from metastatic bone cancer remains poorly understood and resistant to treatment." | 1.32 | Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat. ( Bevan, S; Courade, JP; Dawson, J; Fox, A; Glatt, M; Gonzalez, I; Medhurst, S; Urban, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Xu, Y | 1 |
| Liu, ZL | 1 |
| Tian, YZ | 1 |
| Shen, XH | 1 |
| Remeniuk, B | 1 |
| Sukhtankar, D | 1 |
| Okun, A | 1 |
| Navratilova, E | 1 |
| Xie, JY | 1 |
| King, T | 1 |
| Porreca, F | 1 |
| Díaz-Rodríguez, L | 1 |
| García-Martínez, O | 1 |
| Morales, MA | 1 |
| Rodríguez-Pérez, L | 1 |
| Rubio-Ruiz, B | 1 |
| Ruiz, C | 1 |
| Duan, KZ | 1 |
| Xu, Q | 1 |
| Zhang, XM | 1 |
| Zhao, ZQ | 1 |
| Mei, YA | 1 |
| Zhang, YQ | 1 |
| Fox, A | 1 |
| Medhurst, S | 1 |
| Courade, JP | 1 |
| Glatt, M | 1 |
| Dawson, J | 1 |
| Urban, L | 1 |
| Bevan, S | 1 |
| Gonzalez, I | 1 |
| Weinbroum, AA | 1 |
| Rodríguez Carballeira, M | 1 |
| Coll Roldua, I | 1 |
| Muñoz Rodríguez, FJ | 1 |
| Bastus Piulats, R | 1 |
| Cirera Noguera, L | 1 |
| Espinós Pérez, JC | 1 |
| Fainsinger, RL | 1 |
| Miller, MJ | 1 |
| Bruera, E | 1 |
| Stiefel, F | 1 |
| Morant, R | 1 |
| Benahmed, M | 1 |
| Wibault, P | 1 |
| Court, B | 1 |
| Kple Faget, P | 1 |
| Ammarguellat, H | 1 |
| Pichard, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Epidural Analgesia Initiated in the Preoperative Period in Lower Extremity Osteosarcoma[NCT04945512] | 28 participants (Anticipated) | Interventional | 2021-11-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for diclofenac and Bone Cancer
| Article | Year |
|---|---|
Combined application of diclofenac and celecoxib with an opioid yields superior efficacy in metastatic bone cancer pain: a randomized controlled trial.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Cancer Pai | 2017 |
Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients.
Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, G | 2005 |
8 other studies available for diclofenac and Bone Cancer
| Article | Year |
|---|---|
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Stero | 2015 |
Effects of indomethacin, nimesulide, and diclofenac on human MG-63 osteosarcoma cell line.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Cell Cycle; Cell Differentiation; Cell Line | 2012 |
Targeting A-type K(+) channels in primary sensory neurons for bone cancer pain in a rat model.
Topics: 4-Aminopyridine; Activating Transcription Factor 3; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2012 |
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bone Density; Bone Neoplasms; Cyclooxygenase 2; Cyc | 2004 |
[Colitis induced by non-steroidal anti-inflammatory agents].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Colitis; Diarrhea; Diclofenac; Humans | 1995 |
Morphine intoxication during acute reversible renal insufficiency.
Topics: Acute Kidney Injury; Aged; Bone Neoplasms; Diclofenac; Drug Therapy, Combination; Humans; Male; Morp | 1992 |
Morphine intoxication during acute reversible renal insufficiency.
Topics: Acute Kidney Injury; Aged; Bone Neoplasms; Diclofenac; Humans; Male; Morphine; Pain; Poisoning; Pros | 1991 |
[Efficacy of diclofenac continuous perfusion in hyperalgic bone metastases. Apropos of 20 cases treated at Gustave Roussy Institute].
Topics: Adult; Aged; Bone Neoplasms; Diclofenac; Female; Humans; Infusions, Intravenous; Male; Middle Aged; | 1988 |