Page last updated: 2024-10-26

diclofenac and Blood Loss, Surgical

diclofenac has been researched along with Blood Loss, Surgical in 12 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Blood Loss, Surgical: Loss of blood during a surgical procedure.

Research Excerpts

ExcerptRelevanceReference
"Ketorolac is approved for the relief of postoperative pain but concerns have been raised over a possible risk of serious adverse effects and death."2.70Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery. ( Abdalla, M; Bianchi, PG; Bonnet, F; Camu, F; Ebrahim, S; Escolar, G; Forrest, JB; Greer, IA; Heitlinger, E; Jage, J; Kehlet, H; Langman, MJ; Pocock, S; Samama, MM; Velo, G, 2002)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's5 (41.67)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bongiovanni, T1
Lancaster, E1
Ledesma, Y1
Whitaker, E1
Steinman, MA1
Allen, IE1
Auerbach, A1
Wick, E1
Windfuhr, JP1
Mowafi, HA1
Telmessani, L1
Ismail, SA1
Naguib, MB1
Hegi, TR1
Bombeli, T1
Seifert, B1
Baumann, PC1
Haller, U1
Zalunardo, MP1
Pasch, T1
Spahn, DR1
Rorarius, MG1
Baer, GA1
Siirtola, M1
Lahti, T1
Laippala, P1
Thiagarajan, J1
Bates, S1
Hitchcock, M1
Morgan-Hughes, J1
Mendham, JE1
Mather, SJ1
Subramaniam, R1
Pandit, B1
Sadhasivam, S1
Sridevi, KB1
Kaul, HL1
Schmidt, A1
Björkman, S1
Akeson, J1
Forrest, JB1
Camu, F1
Greer, IA1
Kehlet, H1
Abdalla, M1
Bonnet, F1
Ebrahim, S1
Escolar, G1
Jage, J1
Pocock, S1
Velo, G1
Langman, MJ1
Bianchi, PG1
Samama, MM1
Heitlinger, E1
Anderson, SK1
al Shaikh, BA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056]Phase 4200 participants (Anticipated)Interventional2022-02-08Recruiting
Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173]Phase 4550 participants (Anticipated)Interventional2020-07-22Recruiting
Acute Kidney Injury and Nonsteroidal Anti-inflammatory Drugs in Patients Undergoing High-risk Abdominal or Thoracic Surgery[NCT02553174]50 participants (Actual)Observational2016-06-01Terminated (stopped due to unable to recruit sufficient patients to satisfy study protocols)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for diclofenac and Blood Loss, Surgical

ArticleYear
Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.
    Journal of the American College of Surgeons, 2021, Volume: 232, Issue:5

    Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Blood Transfusion; Diclofe

2021

Trials

9 trials available for diclofenac and Blood Loss, Surgical

ArticleYear
Post-op pain and blood loss in total knee arthroplasty: an RCT using periarticular injection with diclofenac-based multimodal drugs.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:12

    Topics: Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Anti

2014
Preoperative lornoxicam for pain prevention after tonsillectomy in adults.
    Journal of clinical anesthesia, 2011, Volume: 23, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Diclofenac; Double-Blind Metho

2011
Effect of rofecoxib on platelet aggregation and blood loss in gynaecological and breast surgery compared with diclofenac.
    British journal of anaesthesia, 2004, Volume: 92, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Blood Loss, S

2004
Effect of intravenous diclofenac or indomethacin on the emergence from anaesthesia for tonsillectomy.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, General; Arousal; Attention; Awareness; B

1993
Blood loss following tonsillectomy in children. A blind comparison of diclofenac and papaveretum.
    Anaesthesia, 1993, Volume: 48, Issue:2

    Topics: Akathisia, Drug-Induced; Blood Loss, Surgical; Blood Volume; Child; Child, Preschool; Diclofenac; Hu

1993
Comparison of diclofenac and tenoxicam for postoperative analgesia with and without fentanyl in children undergoing adenotonsillectomy or tonsillectomy.
    Paediatric anaesthesia, 1996, Volume: 6, Issue:6

    Topics: Adenoidectomy; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Ch

1996
Preoperative rectal diclofenac versus paracetamol for tonsillectomy: effects on pain and blood loss.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:1

    Topics: Acetaminophen; Administration, Rectal; Adult; Analgesics, Non-Narcotic; Anesthesia; Anti-Inflammator

2001
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Diclofenac in combination with opiate infusion after joint replacement surgery.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Adult; Aged; Antiemetics; Blood Loss, Surgical; Diclofenac; Double-Blind Method; Drug Therapy, Combi

1991

Other Studies

2 other studies available for diclofenac and Blood Loss, Surgical

ArticleYear
[Use of diclofenac for tonsillectomy].
    Der Anaesthesist, 2009, Volume: 58, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Child; Diclofenac; Humans; Postoperat

2009
Retroperitoneoscopic excision of phaeochromocytoma--haemodynamic events, complications and outcome.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste

2000