diclofenac has been researched along with Back Pain in 39 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Back Pain: Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-hoc selection of patient-level data from non-interventional studies with flupirtine MR and diclofenac with respect to patient age (> or = 18 years), duration of treatment (14 +/- 2 days), indication (acute/subacute low/back pain) and first-line use." | 7.79 | [2-week efficacy and tolerability of flupirtine MR and diclofenac in patients with acute low/back pain--results of a post-hoc subgroup analysis of patient-level data from four non-interventional studies]. ( Essner, U; Müller-Schwefe, GH; Uberall, MA, 2013) |
| "A previously healthy 60-year-old man receiving aspirin for primary prevention of cardiovascular disease presented with hemoptysis after 1 week of treatment for his back pain with diclofenac." | 7.77 | Hemoptysis under diclofenac and antiplatelet doses of aspirin. ( Yiannakopoulou, EC, 2011) |
| " Fifteen patients experienced a total of 19 adverse events (AEs), 17 of which were mild to moderate, and 2 of which were severe." | 6.76 | Effectiveness and safety of diclofenac epolamine topical patch 1.3% for the treatment of acute pain due to back strain: an open-label, uncontrolled study. ( Gimbel, J; Jacobs, D; Paterson, C; Pixton, G, 2011) |
| "Tissue necrosis is a rare but serious complication of intramuscular injections." | 5.36 | Skin necrosis after self-administered intramuscular diclofenac. ( Arad, E; Uri, O, 2010) |
| " In clinical conditions marked by acute or chronic pain and inflammation, such as oral surgery, dysmenorrhea, low back pain, renal colic, and biliary colic, as well as in post-traumatic and postoperative conditions, diclofenac sodium, a nonsteroidal anti-inflammatory drug with potent prostaglandin synthetase inhibition, has been shown to be an effective analgesic agent." | 5.06 | Use of diclofenac in analgesia. ( Kantor, TG, 1986) |
| " A diagnosis of ochronosis was made by the observation of bluish-brown pigmentation in the nose and ears, dark urine colors following alkalization, and high levels of homogentisic acid in the urine." | 4.84 | Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature. ( Capkin, E; Karkucak, M; Serdaroğlu, M; Tosun, M; Yayli, S, 2007) |
| "Post-hoc selection of patient-level data from non-interventional studies with flupirtine MR and diclofenac with respect to patient age (> or = 18 years), duration of treatment (14 +/- 2 days), indication (acute/subacute low/back pain) and first-line use." | 3.79 | [2-week efficacy and tolerability of flupirtine MR and diclofenac in patients with acute low/back pain--results of a post-hoc subgroup analysis of patient-level data from four non-interventional studies]. ( Essner, U; Müller-Schwefe, GH; Uberall, MA, 2013) |
| "A previously healthy 60-year-old man receiving aspirin for primary prevention of cardiovascular disease presented with hemoptysis after 1 week of treatment for his back pain with diclofenac." | 3.77 | Hemoptysis under diclofenac and antiplatelet doses of aspirin. ( Yiannakopoulou, EC, 2011) |
| "Presented are the results of four postsurgical pain studies, one study of acute gouty arthritis and nine studies of acute musculoskeletal disorders: acute low back pain, acute painful shoulder, tendinitis and bursitis, and acute sports injuries." | 3.76 | Etodolac: analgesic effects in musculoskeletal and postoperative pain. ( Pena, M, 1990) |
| " However, clinical examination revealed that the patient had put a diclofenac hydroxyethylpyrrolidine plaster, which had been prescribed for lower back pain, inadvertently on a large ulcus cruris." | 3.70 | [Ulcer + ulcer]. ( Christ, AD; Speich, R; Stocker, DN, 1998) |
| " Fifteen patients experienced a total of 19 adverse events (AEs), 17 of which were mild to moderate, and 2 of which were severe." | 2.76 | Effectiveness and safety of diclofenac epolamine topical patch 1.3% for the treatment of acute pain due to back strain: an open-label, uncontrolled study. ( Gimbel, J; Jacobs, D; Paterson, C; Pixton, G, 2011) |
| "Diclofenac was also effective." | 2.71 | [Effectiveness of ketonal and diclofenac in spondylarthrosis complicated with spinal pain]. ( Babadaeva, NM; Khomenko, VV; Riabkova, AA; Shostak, NA, 2003) |
| " But considering that the application of NSAIDs is frequently associated with side effects, a reduction of dosage would be to the patient's benefit." | 2.67 | [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. ( Koehler, CO; Kuhlwein, A; Meyer, HJ, 1990) |
| "Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints." | 2.49 | Comfrey root: from tradition to modern clinical trials. ( Staiger, C, 2013) |
| "Tissue necrosis is a rare but serious complication of intramuscular injections." | 1.36 | Skin necrosis after self-administered intramuscular diclofenac. ( Arad, E; Uri, O, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.51) | 18.7374 |
| 1990's | 9 (23.08) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 8 (20.51) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kiselev, DV | 1 |
| Lavrukhin, VV | 1 |
| Wang, D | 1 |
| Luo, J | 1 |
| Li, JD | 1 |
| Pei, MM | 1 |
| Zhang, W | 1 |
| Oke, KI | 1 |
| Umebese, PF | 1 |
| Uberall, MA | 1 |
| Essner, U | 1 |
| Müller-Schwefe, GH | 1 |
| Zolotovskaya, IA | 1 |
| Davydkin, IL | 1 |
| Rozin, AP | 1 |
| Braun-Moscovici, Y | 1 |
| Balbir-Gurman, A | 1 |
| Chernysheva, TV | 1 |
| Bagirova, GG | 1 |
| Siddiqi, R | 1 |
| Jafri, SA | 1 |
| Uri, O | 1 |
| Arad, E | 1 |
| Levin, OS | 1 |
| Moseĭkin, IA | 1 |
| Yiannakopoulou, EC | 1 |
| Gimbel, J | 1 |
| Jacobs, D | 1 |
| Pixton, G | 1 |
| Paterson, C | 1 |
| Staiger, C | 1 |
| Witzig, M | 1 |
| Bützberger, S | 1 |
| Caravatti, M | 1 |
| Furrer, J | 1 |
| Schulthess, G | 1 |
| Spornraft-Ragaller, P | 1 |
| Ragaller, M | 1 |
| Meurer, M | 1 |
| Shostak, NA | 1 |
| Riabkova, AA | 1 |
| Babadaeva, NM | 1 |
| Khomenko, VV | 1 |
| Yokobori, S | 1 |
| Yokota, H | 1 |
| Yamamoto, Y | 1 |
| Rüster, M | 1 |
| Kiehntopf, M | 1 |
| Gröne, HJ | 1 |
| Wolf, G | 1 |
| Sarifakioglu, E | 1 |
| Capkin, E | 1 |
| Karkucak, M | 1 |
| Yayli, S | 1 |
| Serdaroğlu, M | 1 |
| Tosun, M | 1 |
| Schiltenwolf, M | 1 |
| Althaus, E | 1 |
| Middleton, RS | 1 |
| Stachurski, W | 1 |
| Pienc, A | 1 |
| Tschirdewahn, B | 1 |
| Zimmerman, J | 1 |
| Siguencia, J | 1 |
| Tsvang, E | 1 |
| Gliemroth, J | 1 |
| Heise, S | 1 |
| Missler, U | 1 |
| Stocker, DN | 1 |
| Christ, AD | 1 |
| Speich, R | 1 |
| Mazzone, M | 1 |
| Siciliano, M | 1 |
| Carella, G | 1 |
| Bandelot, JB | 1 |
| Mihout, B | 1 |
| Gentric, A | 1 |
| Pennec, YL | 1 |
| Encinas, A | 1 |
| Romero, FJ | 1 |
| Granados, MI | 1 |
| Cabrerizo, A | 1 |
| Kuhlwein, A | 1 |
| Meyer, HJ | 1 |
| Koehler, CO | 2 |
| Brüggemann, G | 1 |
| Koch, EM | 1 |
| Stratz, T | 1 |
| Pena, M | 1 |
| Kantor, TG | 1 |
| Deray, G | 1 |
| Le Hoang, P | 1 |
| Aupetit, B | 1 |
| Achour, A | 1 |
| Rottembourg, J | 1 |
| Baumelou, A | 1 |
| Simon, L | 1 |
| Blázek, M | 1 |
| Keszthelyi, B | 1 |
| Várhelyi, M | 1 |
| Körösi, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of the Combination Dexketoprofen / Vitamin B vs Dexketoprofen in the Treatment of Pain in Patients With Post-traumatic Cervical Sprain Grade I-II of the Quebec Scale.[NCT05001555] | Phase 3 | 174 participants (Actual) | Interventional | 2021-11-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for diclofenac and Back Pain
| Article | Year |
|---|---|
Comfrey root: from tradition to modern clinical trials.
Topics: Adult; Anti-Inflammatory Agents; Back Pain; Child; Child, Preschool; Comfrey; Diclofenac; Drug Combi | 2013 |
Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature.
Topics: Alkaptonuria; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Ascorbic Acid; Back Pain; Calcino | 2007 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
12 trials available for diclofenac and Back Pain
| Article | Year |
|---|---|
Evaluation of the efficacy of pulsed electromagnetic therapy in the treatment of back pain: a randomized controlled trial in a tertiary hospital in Nigeria.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Combined Modality Therapy; Di | 2013 |
[Effect of nonsteroidal anti-inflammatory drugs on the indicators of cardiovascular risk in patients with acute nonspecific back pain].
Topics: Acute Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cardiovascular Diseases; Cyclo | 2015 |
[Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy].
Topics: Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Dose- | 2009 |
Effectiveness and safety of diclofenac epolamine topical patch 1.3% for the treatment of acute pain due to back strain: an open-label, uncontrolled study.
Topics: Acute Pain; Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida | 2011 |
[Effectiveness of ketonal and diclofenac in spondylarthrosis complicated with spinal pain].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cyclooxygenase Inhibitors; Diclofenac; Dr | 2003 |
A comparison of two analgesic muscle relaxant combinations in acute back pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aspirin; Back Pain; Caffeine; Carisoprodol; C | 1984 |
[Treatment of vertebral and vetebragenous syndrome with Proquazon].
Topics: Analgesics; Back Pain; Diclofenac; Double-Blind Method; Female; Humans; Male; Quinazolines; Spinal D | 1980 |
[Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes].
Topics: Adolescent; Adult; Aged; Back Pain; Diclofenac; Disability Evaluation; Dose-Response Relationship, D | 1990 |
[Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study].
Topics: Adult; Back Pain; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; | 1990 |
[Intramuscular etofenamate in the treatment of acute lumbago. Effectiveness and tolerance in comparison with intramuscular diclofenac-Na].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Female; Flu | 1990 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
Use of diclofenac in analgesia.
Topics: Analgesia; Back Pain; Biliary Tract Diseases; Clinical Trials as Topic; Colic; Diclofenac; Double-Bl | 1986 |
25 other studies available for diclofenac and Back Pain
| Article | Year |
|---|---|
[The use of a fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndrome in patients with discogenic lumbosacral radiculopathy and lumboischialgia].
Topics: Acute Pain; Back Pain; Diclofenac; Humans; Orphenadrine; Radiculopathy | 2023 |
[Case control study on clinical effects of sacrococcygeal manipulation in the treatment of coccyx pain].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Case-Control Studies; Coccyx; Diclofenac; | 2016 |
[2-week efficacy and tolerability of flupirtine MR and diclofenac in patients with acute low/back pain--results of a post-hoc subgroup analysis of patient-level data from four non-interventional studies].
Topics: Acute Disease; Adult; Aged; Aminopyridines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bac | 2013 |
Pulsating back pain associated with tumor necrosis factor-alpha blockade.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rh | 2008 |
[Pharmaco-economic efficiency of the treatment of patients with acute vertebrogenic lumbar pain syndrome].
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cost-Benefit Analysis; Dic | 2008 |
Maternal satisfaction after spinal anaesthesia for caesarean deliveries.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Back Pai | 2009 |
Skin necrosis after self-administered intramuscular diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cellulitis; Diclofenac; Humans; Injections, Intr | 2010 |
Hemoptysis under diclofenac and antiplatelet doses of aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Back Pain; Cardiovascular Diseases; Diclofenac; Dr | 2011 |
[Backache and palmar eczema (SAPHO syndrome)].
Topics: Acquired Hyperostosis Syndrome; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Dia | 2003 |
[Toxic epidermal necrolysis induced by NSAID].
Topics: Aged; Back Pain; Biopsy; Diagnosis, Differential; Diclofenac; Female; Humans; Skin; Stevens-Johnson | 2003 |
Pediatric posterior reversible leukoencephalopathy syndrome and NSAID-induced acute tubular interstitial nephritis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Back Injuries; Back Pain; Cerebral Cortex; C | 2006 |
A Friday afternoon case of apparent anti-glomerular basement nephritis.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Animals; Anti-Glomerular Basement Membrane Disease; | 2006 |
Nicolau syndrome after diclofenac injection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Buttocks; Diclofenac; Erythema; Female; Humans; | 2007 |
[First-line treatment for acute low back pain. Assessment of diclofenac or spinal manipulative therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Combined Modality Therapy; Diclofenac; Double-Bl | 2008 |
[Use of voltaren for the treatment of backache].
Topics: Adult; Aged; Back Pain; Diclofenac; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Phenylaceta | 1980 |
Upper gastrointestinal hemorrhage associated with cutaneous application of diclofenac gel.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; | 1995 |
A 64-year-old man with diabetes and ascending paraplegia.
Topics: Back Pain; Central Nervous System Diseases; Diabetes Complications; Diclofenac; Gas Gangrene; Humans | 1996 |
[Ulcer + ulcer].
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Back Pain | 1998 |
Multiple diclofenac-induced adverse effects.
Topics: Aged; Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Gastritis; | 2000 |
[Myoclonic encephalopathy due to diclofenac].
Topics: Back Pain; Brain; Diclofenac; Humans; Male; Middle Aged; Myoclonus; Phenylacetates | 1978 |
Diclofenac-induced pseudomembranous colitis.
Topics: Aged; Aged, 80 and over; Back Pain; Diclofenac; Enterocolitis, Pseudomembranous; Female; Humans | 1992 |
[The side effects on the distal intestine produced by NSAIDs given rectally].
Topics: Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Female; Huma | 1991 |
Enhancement of cyclosporine A nephrotoxicity by diclofenac.
Topics: Acute Kidney Injury; Back Pain; Cyclosporins; Diclofenac; Drug Synergism; Humans; Male; Middle Aged; | 1987 |
Low back pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Humans; Ketoprofen; Piroxicam | 1987 |
Comparative study of Biarison and Voltaren in acute lumbar pain and lumbo-ischialgia.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics; Back Pain; Diclofenac; Double-Blind Method; | 1986 |