diclofenac and Aura
diclofenac has been researched along with Aura in 8 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of this study was to evaluate the effect of non-steroidal anti-inflammatory diclofenac sodium on the severity of seizures and levels of pro-inflammatory interleukins in animals with kindling model induced by PTZ." | 7.83 | Effect of diclofenac sodium on seizures and inflammatory profile induced by kindling seizure model. ( Coitinho, AS; Glassmann, D; Gomez, R; Marafon, P; Pereira, P; Vieira, V, 2016) |
| " The aim of the current study was to determine the post-treatment effect of aceclofenac on penicillin-induced experimental epilepsy." | 3.85 | Acute effects of aceclofenac, COX-2 inhibitor, on penicillin-induced epileptiform activity. ( Ayyıldız, N; Taşdemir, A; Taşkıran, M, 2017) |
| " The objective of this study was to evaluate the effect of non-steroidal anti-inflammatory diclofenac sodium on the severity of seizures and levels of pro-inflammatory interleukins in animals with kindling model induced by PTZ." | 3.83 | Effect of diclofenac sodium on seizures and inflammatory profile induced by kindling seizure model. ( Coitinho, AS; Glassmann, D; Gomez, R; Marafon, P; Pereira, P; Vieira, V, 2016) |
| "Epilepsy is a disease which affects between 1 and 2% of the population, and a large proportion of these people do not react to currently available anticonvulsant medications, indicating the need for further research into novel pharmacological therapies." | 1.91 | Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions. ( Erbas, O; Erdogan, A; Erdogan, MA; Gurgul, S, 2023) |
| "Diclofenac was used for the in vitro experiment, and its hydroxy metabolite (4'-hydroxydiclofenac) was measured by HPLC." | 1.31 | Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis. ( Hadama, A; Hayashibara, M; Higuchi, S; Ieiri, I; Kitada, M; Mamiya, K; Morita, T; Ninomiya, H; Ohmori, S; Otsubo, K; Tainaka, H; Tashiro, N, 2000) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Javed, L | 1 |
| Hanif, F | 1 |
| Malhi, SM | 1 |
| Zaman, U | 1 |
| Jahan, N | 1 |
| Amir, Q | 1 |
| Javed, A | 1 |
| Malik, AB | 1 |
| Abrar, H | 1 |
| Erdogan, A | 2 |
| Erdogan, MA | 2 |
| Gurgul, S | 2 |
| Erbas, O | 2 |
| Elgarhi, R | 1 |
| Shehata, MM | 1 |
| Abdelsameea, AA | 1 |
| Salem, AE | 1 |
| Vieira, V | 1 |
| Glassmann, D | 1 |
| Marafon, P | 1 |
| Pereira, P | 1 |
| Gomez, R | 1 |
| Coitinho, AS | 1 |
| Taşkıran, M | 1 |
| Taşdemir, A | 1 |
| Ayyıldız, N | 1 |
| Ieiri, I | 1 |
| Tainaka, H | 1 |
| Morita, T | 1 |
| Hadama, A | 1 |
| Mamiya, K | 1 |
| Hayashibara, M | 1 |
| Ninomiya, H | 1 |
| Ohmori, S | 1 |
| Kitada, M | 1 |
| Tashiro, N | 1 |
| Higuchi, S | 1 |
| Otsubo, K | 1 |
| Al-Waili, NS | 1 |
Reviews
1 review available for diclofenac and Aura
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
Other Studies
7 other studies available for diclofenac and Aura
| Article | Year |
|---|---|
Diclofenac sodium enhances the antiepileptic effect of levetiracetam in pilocarpine induced epileptic mice model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Behavior, Animal; Convulsants; Di | 2021 |
Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions.
Topics: Animals; Anticonvulsants; Diclofenac; Disease Models, Animal; Epilepsy; Myoclonus; Pentylenetetrazol | 2023 |
Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions.
Topics: Animals; Anticonvulsants; Diclofenac; Disease Models, Animal; Epilepsy; Myoclonus; Pentylenetetrazol | 2023 |
Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions.
Topics: Animals; Anticonvulsants; Diclofenac; Disease Models, Animal; Epilepsy; Myoclonus; Pentylenetetrazol | 2023 |
Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions.
Topics: Animals; Anticonvulsants; Diclofenac; Disease Models, Animal; Epilepsy; Myoclonus; Pentylenetetrazol | 2023 |
Effects of Diclofenac Versus Meloxicam in Pentylenetetrazol-Kindled Mice.
Topics: Animals; Anticonvulsants; Diclofenac; Epilepsy; Kindling, Neurologic; Male; Meloxicam; Mice; Pentyle | 2020 |
Effect of diclofenac sodium on seizures and inflammatory profile induced by kindling seizure model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cerebral Cortex; Diazepam; Diclof | 2016 |
Acute effects of aceclofenac, COX-2 inhibitor, on penicillin-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cyclooxygenase 2 Inhibitors; Diclofenac; Epilepsy; Male; | 2017 |
Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis.
Topics: Adult; Alleles; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon H | 2000 |
Diclofenac sodium and intractable epilepsy.
Topics: Adult; Diclofenac; Epilepsy; Humans; Male | 1986 |